Registration Dossier
Registration Dossier
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EC number: 206-056-4 | CAS number: 298-07-7
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
In all in-vitro genetic toxicity assays (Ames tests, MNT, HGPRT test), bis(2-ethylhexyl) hydrogen phosphate was negative.
Justification for selection of genetic toxicity endpoint
The results of 3 Ames tests, an in vitro MNT test and the HPRT test were considered.
Short description of key information:
Bis(2-ethylhexyl) hydrogen phosphate was investigated in several Salmonella/microsome tests (Ames tests). Result: negative, no evidence of mutagenic activity of bis(2-ethylhexyl) hydrogen phosphate was seen (with and without mutagenic activation). Additional, bis(2-ethylhexyl) hydrogen phosphate was evaluated as negative in an in-vitro MNT and also in a HPRT test.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Due to the negative reaults in all available in-vitro genetic toxicity tests a classification is not justified.
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