Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 207-662-1 | CAS number: 487-68-3
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
The BCF in steady-state of the test substance was determined to be 17 (dimensionless). No significant bioaccumulation in fish is therefore to be expected.
Key value for chemical safety assessment
- BCF (aquatic species):
- 17 dimensionless
Additional information
The bioaccumulation of the test substance was determined in a study according to OECD guideline 305 and in compliance with GLP criteria. In this study carp (Cyprinus carpio) were exposed for 28 days to nominal test substance concentrations of 20 or 2 µg/L in a flow-through system. Nominal concentrations were analytically verified and determined at 17.5 or 1.64 µg/L, respectively. The mean concentrations of the metabolite 2,4,6-trimethyl benzoic acid (MEC) were 2.47 and 0.317 µg/L, respectively. In the high concentration group, the steady state was reached by day 28 and the BCF was calculated to be 17 (dimensionless). In the low concentration group, the steady state was also reached by day 28. The BCF was however not calculated because the test substance in test fish were below the limit of quantitation. The lipid contents in test fish increased from 2.96% before the start of the experiment to 4.13% after terminating exposure. These increases in lipid contents were attributed to growth of test fish.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
