Registration Dossier
Registration Dossier
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EC number: 208-167-3 | CAS number: 513-77-9
pH
Administrative data
- Endpoint:
- pH
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2010-09-01
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- One liter of demineralised water has been adjusted to pH = 1,5 by adding HCl 37%; 300 ml of the previous solution has been spilled in one glass beaker and the temperature has been regulated at 37°C. Agitating sufficient quantity of the Ba-substance has been dissolved to reach a saturated solution keeping the temperature at 37 °C. After 15 minutes additional reaction time the solution has been filtered with preheated filtering equipment. The barium content in the filtrate has been determined by gravimetric analysis (the filtrate had for BaCO3 test a pH = 6.8).
- GLP compliance:
- no
- Other quality assurance:
- other: The activity of the Laboratory Department is certified according to the ISO 9001:2008 standard.
Test material
- Reference substance name:
- Barium carbonate
- EC Number:
- 208-167-3
- EC Name:
- Barium carbonate
- Cas Number:
- 513-77-9
- Molecular formula:
- BaCO3
- IUPAC Name:
- barium carbonate
- Test material form:
- solid
- Details on test material:
- - Name of test material (as cited in study report): Barium carbonate VL600S
- Batch No.: 010420
- Chemical description: Barium carbonate
- Molecular formula: BaCO3
- Molecular weight: 197.34 g/mol
- Physical state: Solid, white powder
- Storage condition of test material: Ambient temperature, dark, dry and original containers
- Expiration date of the batch: Unlimited total self life if stored in tightly closed original container at room temperature, in any case at least 3 years
Constituent 1
Results and discussion
pH value
- pH value:
- 6.8
- Temp.:
- 37 °C
- Concentration:
- 3.67 g/L
- Remarks on result:
- other: HCl media pH 1.5
Applicant's summary and conclusion
- Conclusions:
- 3.67 g/L barium carbonate dissolves in a artificial gastic fluid of HCl solution (pH 1.5) at 37°C. After dissolution the pH value of the solution was: 6.8
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