Registration Dossier
Registration Dossier
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EC number: 208-952-0 | CAS number: 548-61-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48 h): 10.448 mg/L (OECD 202)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 10.448 mg/L
Additional information
One study is available investigating the short-term toxicity of
4,4',4''-methylidynetrianiline (EC No. 208-952-0) to aquatic
invertebrates (Spoo-Klöppel, 2015). Daphnia magna was exposed to nominal
concentrations of 1.9, 4.3, 9.4, 20.7, 45.5, 100 mg/L. The actual test
substance concentrations in the test medium were verified by HPLC/UV-VIS
analysis at 0 and 48 h. It was shown that the initially measured
concentrations were lower compared to the nominal concentrations.
However, the initial measured concentrations did not differ > 20 % from
the measured concentrations after 48 h. Thus, the effect concentrations
were based on the initially measured concentrations.
After 24 h of exposure no immobilization was recorded, whereas 50 %
immobilization was observed after 48 h at the highest concentration
tested. An EC50 (48 h) of 10.448 mg/L was calculated by probit analysis.
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