Salicylonitrile

Surface tension

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Remarks:

Limited detail on the time dependance of the measured solutions.

Qualifier:

no guideline followed

Principles of method if other than guideline:

Electric potential and surface tension measurements of the surface of aqueous solutions of o-, m-, p-cyanophenols as a function of pH and concentration.

GLP compliance:

no

Surface tension:

71.2 mN/m

Temp.:

20 °C

Conc.:

1 g/L

Surface tension:

61.6 mN/m

Temp.:

20

Conc.:

7 g/L

Data extracted by the Registrant from the graphical plot for o-cyanophenol (Figure 1) in the original report.

Conclusions:

Original article in Polish. Limited details on experimental methods and lack of time dependance leaves some uncertainty in results.

Reference 2

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

07-Jun-2010 to 19-Jul-2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Deviations:

no

GLP compliance:

no

Type of method:

OECD harmonised ring method

Surface tension:

69.9 mN/m

Temp.:

20 °C

Conc.:

1.005 g/L

Remarks on result:

other: Average of three values

The calibration factor Φ_bwas determined to be 1.0318 for double distilled water.

The table below shows the individual measurements for the surface tension of the aqueous test item solution. From these, the mean and the corrected value for the given solution were calculated. The tabulated values represent rounded results obtained from calculation using the exact raw data.

 

Determination of Surface Tension for the Test Item Solution

Time expired [hours:min]	Temperature [°C]	Surface tension measured [mN/m]	[mN/m]
			mean value	mean value corrected for calibration	s1corrected for Harkins-Jordan
			(σ *)	(σ1)	(σ )
First sample
00:30	19.7	67.6	67.37	69.51	69.39
00:31	19.7	67.4
00:32	19.7	67.3
00:33	19.7	67.3
00:34	19.7	67.3
00:35	19.7	67.3
Second sample
00:31	20.2	68.4	68.32	70.49	70.43
00:32	20.2	68.4
00:33	20.2	68.3
00:34	20.2	68.3
00:35	20.2	68.3
00:36	20.2	68.2

 

Mean value from both samples: σ = 69.9 mN/m.

Conclusions:

The duplicate results were in good agreement; the study is considered to be reliable.

Executive summary:

The surface tension of the substance in water (at a concentration of about 1 g/L) was determined to be 69.9 mN/m at 20.0 °C ± 0.3 °C.

Description of key information

69.9 mN/m, 20°C, 1.005g/L, OECD 115, ring method, Weissenfeld 2010
71.2 mN/m, 20°C, 1g/L, Siwek 1971

Key value for chemical safety assessment

Surface tension:

69.9

in mN/m at 20°C and concentration in mg/L:

1 005

Additional information

Inspection of the molecular structure indicated no structural alerts associated with surface activity. A distinct hydrophilic head-group and hydrophobic tail are not present in the molecule and surface activity is thus not expected. However, data from Siwek (1971) demonstrated that surface activity was present at higher concentrations. A guideline study gave similar results at a concentration of 1g/L and is the value carried forward for risk assessment, classification and labeling. The surface tension for a 1 g/L solution was >60 mN/m at 20°C, and hence does not meet the criteria for surface activity according to Regulation (EC) No. 440/2008, A5.