Registration Dossier
Registration Dossier
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EC number: 212-153-2 | CAS number: 765-69-5
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Referenceopen allclose all
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- QSAR Toolbox 3.1.0.21
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- T.E.S.T. version 4.1
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July2008
Test material
- Reference substance name:
- 2-methylcyclopentane-1,3-dione
- EC Number:
- 212-153-2
- EC Name:
- 2-methylcyclopentane-1,3-dione
- Cas Number:
- 765-69-5
- Molecular formula:
- C6H8O2
- IUPAC Name:
- 2-methylcyclopentane-1,3-dione
Constituent 1
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 723.155
- Nominal / measured:
- estimated
- Remarks on result:
- not measured/tested
Any other information on results incl. tables
- Sublethal observations / clinical signs:
Software Database / Method Endpoint Test duration Species Predicted value (mg/L) QSAR Toolbox Aquatic OASIS LC50 96 h Pimephales promales 426 T.E.S.T. Consensus method LC50 96 h Fathead minnow 466,46 T.E.S.T. Hiearchical Clustering Method LC50 96 h Fathead minnow 1045,86 T.E.S.T. Single Model Method LC50 96 h Fathead minnow 923,29 T.E.S.T. Group Contribution Method LC50 96 h Fathead minnow 515,5 T.E.S.T. Nearest neighbor method LC50 96 h Fathead minnow 961,82 Inferential result 723,155 mg/L
Applicant's summary and conclusion
- Conclusions:
- According to (Q)SAR modells: QSAR Toolbox, T.E.S.T. the predicted values indicated that methyl-ciklopentanedione is not hazardous to fishes. The result does not meet the requirement of any Aquatic Acute Category.
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