N-1,3-dimethylbutyl-N'-phenyl-p-phenylenediamine

Short-term toxicity to fish

Description of key information

The acute toxicity of N-(1,3-dimethylbutyl)-N'-phenylbenzene-1,4-diamine to fish was tested according to OECD TG 203
"Fish, acute toxicity test". After 96 hours of exposure a LC50 of 0.028 mg/L was obtained.
(Japanese Ministry of the Environment, Government of Japan, 2001)

Key value for chemical safety assessment

Fresh water fish

Fresh water fish

Effect concentration:

0.028 mg/L

Additional information

Tests in fish

Obviously, fish is the most sensitive organism for the family of PPDs and their degradation products. The lowest effect values were found for 6PPD (0.028 mg/L). However the recovery was only about 30%. Primary hydrolysis products (4 -HDPA and

N-phenylbenzoquinone-imine have not been analysed but they are expected to have been formed during the test. Thus, the effect measured covers not only 6PPD but also the hydrolysis products. It is therefore anticipated that the effect value based only on 6PPD is higher. The effect value

for p-hydroquinone (0.044 mg/L) is rather close to the value for 6PPD.

For 4-HDPA and N-phenylbenzoquinone-imine only calculated values are available. The calculated values should be used only for a rough estimation due to the high uncertainty of the method. However they show a trend: The effect values of these three intermediate compounds to fish are at a higher level and there is no indication for a higher toxicity exceeding those for 6PPD or p-hydroquinone.