Registration Dossier
Registration Dossier
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EC number: 221-573-5 | CAS number: 3147-75-9
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
No toxicokinetic data are available for the test substance. The substance is a phenolic benzotriazole with a phenolic hydroxygroup that can be used for phase II conjugation. Experimental data is available for a related substance that has a much shorter alkyl side chain (methyl versus isooctyl) and is of higher solubility in water. This read-across substance (CAS 2440-22-4) was absorbed rapidly in the gastro-intestinal tract and presence in liver and kidney was confirmed experimentally. Elimination was observed predominantly via urine (within 48 hours) and to a lower proportion via feces. There was no evidence of a bioaccumulation potential.
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
Additional information
A separate read-across document with mechanistic considerations is attached at the end of the Chemical Safety Report.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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