Registration Dossier
Registration Dossier
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EC number: 257-827-7 | CAS number: 52301-70-9
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- Principles of method if other than guideline:
- None
- GLP compliance:
- yes
- Type of method:
- HPLC estimation method
- Media:
- other: HPLC
- Test temperature:
- None
- Details on study design: HPLC method:
- EQUIPMENT
- Type, material and dimension of analytical (guard) column: XSelect HSS Cyano, 5 μm (150 x 4.6 mm id)
- Detection system: Ultra-violet (UV)
MOBILE PHASES
- Type: Methanol: [pH 7 (phosphate) buffer solution*] (55:45 v/v)
- Experiments with additives carried out on separate columns: yes
- pH: 7.1 - Analytical monitoring:
- yes
- Details on sampling:
- None
- Details on matrix:
- None
- Details on test conditions:
- None
- Computational methods:
- None
- Key result
- Type:
- Koc
- Value:
- > 17.8 dimensionless
- Key result
- Type:
- log Koc
- Value:
- > 1.25 dimensionless
- Details on results (HPLC method):
- None
- Adsorption and desorption constants:
- None
- Recovery of test material:
- None
- Concentration of test substance at end of adsorption equilibration period:
- None
- Concentration of test substance at end of desorption equilibration period:
- None
- Details on results (Batch equilibrium method):
- None
- Statistics:
- None
- Validity criteria fulfilled:
- yes
- Conclusions:
- The adsorption coefficient of the test material has been determined to be less than 17.8, log10 Koc less than 1.25, using the HPLC screening method.
- Executive summary:
The adsorption coefficient of the test material has been determined to be less than 17.8, log10 Koc less than 1.25, using the HPLC screening method, designed to be compatible with Method C.19 Adsorption Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 121 of the OECD Guidelines for Testing of Chemicals, 22 January 2001. These values indicate that the test item has very high mobility.
Reference
None
Description of key information
The adsorption coefficient of the substance has been determined to be less than 17.8, log10Koc less than 1.25, using the HPLC screening method, designed to be compatible with Method C.19 Adsorption Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 121 of the OECD Guidelines for Testing of Chemicals, 22 January 2001. These values indicate that the test item has very high mobility.
[LogKoc: 1.25]
Key value for chemical safety assessment
- Koc at 20 °C:
- 17.8
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
