2-[methyl[(nonafluorobutyl)sulphonyl]amino]ethyl methacrylate

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

14 Jul - 01 Aug 2014

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Guideline study and GLP compliant, but was done at temperatures above the melting point and provided the vapor pressure of the subcooled liquid rather than the solid material.

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

not applicable

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

not applicable

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Deviations:

not applicable

GLP compliance:

yes

Type of method:

effusion method: by loss of weight or by trapping vaporisate

Temp.:

20 °C

Vapour pressure:

<= 0.5 Pa

Remarks on result:

other: (≤ 3.8E-03 mm Hg)

Temp.:

25 °C

Vapour pressure:

<= 0.89 Pa

Remarks on result:

other: (≤ 6.7E-03 mm Hg)

The results of the isothermal TGA analysis for the test substance and the vapor pressure at 20 °C and 25 °C are shown in Fig.2 and Fig.3. With the data from the first two trials, it was found that the plot of the log P of the test substance as a function of the reciprocal temperatures had a coefficient of correlation (r) of < 0.99. An additional trial was performed. Using the data from the second and third trials, the coefficient of correlation (r) was > 0.99. Therefore, data from the first trial was not used in the determination of the vapor pressure of the test substance.

Conclusions:

The vapor pressure of C4 sulfonamido methacrylate was ≤ 0.50 Pa at 20 °C and ≤ 0.89 Pa at 25 °C as determined by the OECD 104 method.

Executive summary:

The vapor pressure of C4 sulfonamido methacrylate was tested using the isothermal TGA effusion method. The vapor pressure was determined as the mean of two trials done under comparable conditions. Measurements were taken above the substance melting point with extrapolation to lower temperatures. The calculated vapor pressures are therefore those of the subcooled liquid, with the solid having a lower vapor pressure. Vapor pressures are therefore expressed as an upper limit for the solid. The study was conducted in accordance with the OECD 104 method and was GLP compliant; however due to the fact that the study was conducted above the melting point and provided the vapor pressure of the subcooled liquid rather than the solid material, the study is considered reliable with restrictions.

Description of key information

The vapor pressure of C4 sulfonamido methacrylate was ≤ 0.50 Pa at 20 °C and ≤ 0.89 Pa at 25 °C as determined by the OECD 104 method.

Additional information

The vapor pressure of C4 sulfonamido methacrylate was tested using the isothermal TGA effusion method. The vapor pressure was determined as the mean of two trials done under comparable conditions. Measurements were taken above the substance melting point with extrapolation to lower temperatures. The calculated vapor pressures are therefore those of the subcooled liquid, with the solid having a lower vapor pressure. Vapor pressures are therefore expressed as an upper limit for the solid. The study was conducted in accordance with the OECD 104 method and was GLP compliant; however due to the fact that the study was conducted above the melting point and provided the vapor pressure of the subcooled liquid rather than the solid material, the study is considered reliable with restrictions.