Registration Dossier
Registration Dossier
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EC number: 268-734-6 | CAS number: 68134-22-5
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- Test procedure according to method of Analytical Expert Group ETAD (Ecological and Toxicological Association of Dyes and Organic Pigment Manufacturer)
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- other: Analytical Expert Group ETAD
- Version / remarks:
- method for substances with very low solubility in both, water and n-octanol
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
- Analytical method:
- photometric method
- Type:
- Pow
- Partition coefficient:
- 133.1
- Temp.:
- 24 °C
- pH:
- ca. 7
- Type:
- log Pow
- Partition coefficient:
- 2.12
- Temp.:
- 24 °C
- pH:
- ca. 7
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- Test procedure according to method of Analytical Expert Group ETAD (Ecological and Toxicological Association of Dyes and Organic Pigment Manufacturer)
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- other: Analytical Expert Group ETAD
- Version / remarks:
- method for substances with very low solubility in both, water and n-octanol
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
- Analytical method:
- photometric method
- Type:
- Pow
- Partition coefficient:
- 133.1
- Temp.:
- 24 °C
- pH:
- ca. 7
- Type:
- log Pow
- Partition coefficient:
- 2.12
- Temp.:
- 24 °C
- pH:
- ca. 7
- Endpoint:
- partition coefficient
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- the partition coefficient of hardly soluble organic pigments is determined by an estimation method (solubilty ratio). Method and test procedure had been elaborated by ETAD. The determination of the water solubility and the n-octanol solubilty of the nanomaterial is covered by read-across based on the corresponding results of the bulk material. Consequently read-across of the estimated partition coefficient is also performed.
- Reason / purpose for cross-reference:
- read-across source
- Type:
- log Pow
- Partition coefficient:
- 2.12
- Temp.:
- 24 °C
- pH:
- ca. 7
Referenceopen allclose all
The octanol and the water solubility were both determined at 24-25 °C.
It is not possible to enter a temperature range in the field above, therefore 24 °C was taken as the temperature value.
Calculation:
log Kow = logP = log (c(n-octanol)/c(water))
(c: individual solubilities; see below).
|
PY 154 |
Octanol solubility [µg/L] |
1890 |
Water solubility [µg/L] |
14.2 |
POW |
133.1 |
log POW |
2.12 |
The octanol and the water solubility were both determined at 24-25 °C.
It is not possible to enter a temperature range in the field above, therefore 24 °C was taken as the temperature value.
Calculation:
log Kow = logP = log (c(n-octanol)/c(water))
(c: individual solubilities; see below).
|
PY 154 |
Octanol solubility [µg/L] |
1890 |
Water solubility [µg/L] |
14.2 |
POW |
133.1 |
log POW |
2.12 |
Description of key information
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 2.12
- at the temperature of:
- 23 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
