Registration Dossier
Registration Dossier
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EC number: 286-273-9 | CAS number: 85203-82-3
Endpoint summary
Administrative data
Description of key information
Not skin sensitiser.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
Justification for classification or non-classification
According to the CLP Regulation (EC 1272/2008), skin sensitiser is a substance that will lead to an allergic response following skin contact.
In case of a guinea pig maximisation test, a response of at least 30 % of the animals, responding at > 1 % intradermal induction, is considered as positive. Under the experimental conditions employed, no animals of the test group showed skin reactions 24 and 48 hours upon challenge with test substance at 5 % concentration.
Moreover, in a LLNA, a stimulation index > or = 3 is considered as a positive response. Under experimental conditions adopted in a LLNA, all tested concentrations produced a stimulation index below 1.6.
Based on available experimental findings, no classification applied to the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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