Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 300-227-8 | CAS number: 93924-33-5 A distillate obtained from the redistillation of a complex combination of hydrocarbons obtained by the distillation of the effluents from a severe catalytic hydrotreatment of paraffins. It boils in the range of approximately 190°C to 330°C (374°F to 594°F).
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://chesar.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_toxicological-information.png)
Toxicological Summary
- Administrative data
- Workers - Hazard via inhalation route
- Workers - Hazard via dermal route
- Workers - Hazard for the eyes
- Additional information - workers
- General Population - Hazard via inhalation route
- General Population - Hazard via dermal route
- General Population - Hazard via oral route
- General Population - Hazard for the eyes
- Additional information - General Population
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
Workers - Hazard for the eyes
Additional information - workers
Workers: Other Gas Oils (Non-Carcinogenic)
Effect | Route | DNEL | Dose Descriptor | Modified Dose Descriptor and Assessment Factors | |
Acute Exposure | Systemic | Dermal | (a) | ||
Inhalation | 5000 mg/m3/ 15 min (for lethality) [aerosol] | 1560 mg/m3/4 h (NOAEC based on lethality in acute inhalation study in rats) | Dose descriptor was modified to correct starting point of 16,723 mg/m3/15 min by adjustment for duration of exposure and level of activity. Then a total AF of 7.5 was applied for inter- and intraspecies differences. | ||
Local | Dermal | (a) | |||
Inhalation | (a) | ||||
Long-Term Exposure | Systemic (b) | Dermal | 2.9 mg/kg/8h | 30 mg/kg/day (NOAEL based on on increased liver and spleen weights, altered bone marrow function (decreased haematopoiesis, red blood cell count, haemoglobin, and haematocrit) and liver histopathology in rats) | Dose descriptor was modified to correct starting point of 58.1 mg/kg/day by adjustment for dermal absorption.. Then a total AF of 24 was applied for subchronic to chronic and inter- and intraspecies differences. |
Inhalation | 16 mg aerosol /m3/8h [aerosol] | 30 mg/kg/day (NOEL based on increased resorption, incomplete skeletal ossification, decreased foetal weights and decreased litter size in a dermal developmental toxicity study in rats with dosing on GD 0-19) | Dose descriptor was modified to correct starting point of 205.1 mg/m3/8 h by adjustment for dermal absorption, extrapolation from dermal to inhalation route, and ventilation in workers. Then a total AF of 7.5 was applied for inter- and intraspecies and remaining differences. | ||
Local | Dermal | (a) for 13-wk exposures and | |||
(c) for chronic exposures (dermal carcinogen) | |||||
Inhalation | (a) |
a) No hazard identified for this route (data available)
b) Long-term systemic effects include non-reproductive effects and developmental/reproductive effects. Lowest DNEL is shown.
c) No-threshold effect and/or no dose-response information available
Worker: Carcinogenic or Unknown Other Gas Oils
|
Effect |
Route |
DNEL |
Dose Descriptor |
Modified Dose Descriptor and Assessment Factors |
Acute Exposure |
Systemic |
Dermal |
(a) |
|
|
Inhalation |
5000 mg/m3/ 15 min (for lethality) [aerosol] |
1560 mg/m3/4 h (NOAEC based on lethality in acute inhalation study in rats) |
Dose descriptor was modified to correct starting point of 16,723 mg/m3/15 min by adjustment for duration of exposure and level of activity. Then a total AF of 7.5 was applied for inter- and intraspecies differences. |
||
Local |
Dermal |
(a) |
|
|
|
Inhalation |
(a) |
|
|
||
Long-Term Exposure |
Systemic (b) |
Dermal |
2.9 mg/kg/8h |
30 mg/kg/day (NOAEL based onon increased liver and spleen weights, altered bone marrow function (decreased haematopoiesis, red blood cell count, haemoglobin, and haematocrit) and liver histopathologyin rats) |
Dose descriptor was modified to correct starting point of 58.1 mg/kg/day by adjustment for dermal absorption.. Then a total AF of 24 was applied for subchronic to chronic and inter- and intraspecies differences. |
Inhalation |
16 mg aerosol /m3/8h [aerosol] |
30 mg/kg/day (NOEL basedon increased resorption, incomplete skeletal ossification, decreased foetal weights and decreased litter sizein a dermal developmental toxicity study in rats with dosing on GD 0-19)
|
Dose descriptor was modified to correct starting point of 205.1 mg/m3/8 h by adjustment for dermal absorption, extrapolation from dermal to inhalation route, and ventilation in workers. Then a total AF of 7.5 was applied for inter- and intraspecies and remaining differences. |
||
Local |
Dermal |
(a) for 13-wk exposures and (c) for chronic exposures (dermal carcinogen) |
|
|
|
Inhalation |
(a) |
|
|
a) No hazard identified for this route (data available)
b) Long-term systemic effects include non-reproductive effects and developmental/reproductive effects. Lowest DNEL is shown.
c) No-threshold effect and/or no dose-response information available
General Population - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard via oral route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard for the eyes
Additional information - General Population
General Population Other Gas Oils
|
Effect |
Route |
DNEL |
Dose Descriptor |
Modified Dose Descriptor and Assessment Factors |
Acute Exposure |
Systemic |
Dermal |
(a) |
|
|
Inhalation |
3000 mg/m3/ 15 min (for lethality) [aerosol] |
1560 mg/m3/4 h (NOAEC based on lethality in acute inhalation study in rats) |
Dose descriptor was modified to correct starting point of 16,723 mg/m3/15 min by adjustment for duration of exposure and level of activity. Then a total AF of 7.5 was applied for inter- and intraspecies differences. |
||
Local |
Dermal |
(a) |
|
|
|
Inhalation |
(a) |
|
|
||
Long-Term Exposure |
Systemic (b) |
Dermal |
1.3 mg/kg/8h |
30 mg/kg/day (NOAEL based onon increased liver and spleen weights, altered bone marrow function (decreased haematopoiesis, red blood cell count, haemoglobin, and haematocrit) and liver histopathologyin rats) |
Dose descriptor was modified to correct starting point of 58.1 mg/kg/day by adjustment for dermal absorption.. Then a total AF of 24 was applied for subchronic to chronic and inter- and intraspecies differences. |
Inhalation |
4.8 mg aerosol /m3/8h [aerosol] |
30 mg/kg/day (NOEL basedon increased resorption, incomplete skeletal ossification, decreased foetal weights and decreased litter sizein a dermal developmental toxicity study in rats with dosing on GD 0-19)
|
Dose descriptor was modified to correct starting point of 205.1 mg/m3/8 h by adjustment for dermal absorption, extrapolation from dermal to inhalation route, and ventilation in workers. Then a total AF of 7.5 was applied for inter- and intraspecies and remaining differences. |
||
Local |
Dermal |
(a) for 13-wk exposures and (c) for chronic exposures (dermal carcinogen) |
|
|
|
Inhalation |
(a) |
|
|
a) No hazard identified for this route (data available)
b) Long-term systemic effects include non-reproductive effects and developmental/reproductive effects. Lowest DNEL is shown.
c) No-threshold effect and/or no dose-response information available
General Population Carcinogenic or Unknown Other Gas Oils
|
Effect |
Route |
DNEL |
Dose Descriptor |
Modified Dose Descriptor and Assessment Factors |
Acute Exposure |
Systemic
|
Dermal |
(a) |
|
|
Inhalation |
(a) |
|
|
||
Local |
Dermal |
(a) |
|
|
|
Inhalation |
(a) |
|
|
||
Long-Term Exposure |
Systemic (b) |
Dermal |
(a) |
|
|
Inhalation |
(a) |
|
|
||
Oral |
1.3 mg/kg/24h |
30 mg/kg/day (NOAEL based onon increased liver and spleen weights, altered bone marrow function (decreased haematopoiesis, red blood cell count, haemoglobin, and haematocrit) and liver histopathologyin rats)
|
Dose descriptor was modified to correct starting point of 41.5 mg/kg/24 h by adjustments for dermal absorption, dermal to oral route, and duration and frequency of daily dosing. Then AF of 40 was applied for inter- and intraspecies differences and for total duration. |
||
Local |
Dermal |
(a) |
|
|
|
Inhalation |
(a) |
|
|
a) No DNEL needed since no exposure expected
b) Long-term systemic effects include developmental/reproductive effects. Lowest DNEL is shown.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)