Registration Dossier
Registration Dossier
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EC number: 310-094-8 | CAS number: 102242-62-6 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Zanthoxylum, Rutaceae.
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
Test material
- Reference substance name:
- Zanthoxylum, ext.
- EC Number:
- 310-094-8
- EC Name:
- Zanthoxylum, ext.
- Cas Number:
- 102242-62-6
- Molecular formula:
- NA
- IUPAC Name:
- Zanthoxylum, ext.
- Test material form:
- liquid: viscous
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- 0.022 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- ca. 7
Any other information on results incl. tables
| Medium | Temp (°C) | Flow rate (mL/h) | Solubility (g/L) | Mean +- SD (g/L) |
Pure water |
20 |
12.5 |
0.0208 - 0.0201 - 0.0193 - 0.0218 - 0.0189 |
0.0202 +-0.00117 |
Medium |
Temp (°C) |
Flow rate (mL/h) |
Solubility (g/L) | Mean +- SD (g/L) |
| Pure water | 20 | 25 | 0.01178 - 0.0206 - 0.0229 - 0.0239 - 0.0230 | 0.0217 +-0.00247 |
Applicant's summary and conclusion
- Conclusions:
- The means calculated on the two tests at the different flows, have a repeatability of less than 7 %, then the solubility is 0.02095 g/L.
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