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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

LC50 (96 h) > 100 mg/L for Brachydanio rerio (OECD 203, limit test)

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
100 mg/L

Additional information

One GLP study according to OECD Guideline 203 was performed in order to investigate the toxicity of Y-15099 (CAS 220727-26-4) to freshwater fish (Bätscher, 2001). The zebra fish, Brachydanio rerio, was exposed to a filtered test solution of nominal 100 mg/L for 96 h. No mortality and no signs of intoxication were detected resulting in a NOEC of = 100 mg/L and a LC50 of > 100 mg/L. Chemical analysis of test solutions showed a drop of test item concentration in the test vessels (mean measured concentration: 0.017 mg/L) which is related to the hydrolytic instability of the test substance. Therefore, the hydrolytic degradation products were tested in this study as well.