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EC number: 446-800-7 | CAS number: 175357-18-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2009-06-19 to 2010-04-12
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP Guideline Study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2010
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- gas saturation method
- Remarks:
- at 60°C
Test material
- Reference substance name:
- LCA 08042
- IUPAC Name:
- LCA 08042
- Details on test material:
- - Name of test material (as cited in study report): LCA08042
- Substance type: white and beige solid
- Physical state: solid
- Analytical purity: 99.4%
- Lot/batch No.: 0826000002
- Expiration date of the lot/batch: September 16, 2001
- Storage condition of test material: At room temperature (about 20°C)
Constituent 1
Results and discussion
Vapour pressureopen allclose all
- Temp.:
- 60 °C
- Vapour pressure:
- < 0 Pa
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: model calculation based on the Watson Correlation
Any other information on results incl. tables
The results and the amount of nitrogen used to calculate the vapor pressure of the individual experiments are summarized in Table 2 (see attached). The tabulated values represent rounded results that were obtained by calculation using the exact raw data.
Applicant's summary and conclusion
- Conclusions:
- Based on the gas saturation method, the vapor pressure of LCA08042 was measured at test temperature of 60 °C and was determined to be <3.4 x 10-5 Pa at 60 °C. The vapor pressure of LCA08042 at 60 °C is considered to be below the recommended limit of 10-5 Pa, as given in the Guidelines. Therefore, no further experimental testing was necessary. Additionally a model calculation based on the Watson Correlation was performed: 5.89 x 10-7 Pa (calculated for 25 °C).
- Executive summary:
The vapor pressure of LCA08042 was determined according to the EEC Directive 92/69, A.4 “Vapour Pressure” (1992), to the OECD guideline No. 104, “Vapour Pressure” (2006) and to the Council Regulation EC No. 440/2008, A4 “Vapour Pressure” (2008) using the gas saturation method.
Based on the information available, the vapor pressure of LCA08042 was measured at elevated temperature. The experiments were performed at 60 °C. To ensure saturation control, three different flow rates were used. The results and the amount of nitrogen used to calculate the vapor pressure of the individual experiments are summarized in Table 2 (see attached). The tabulated values represent rounded results that were obtained by calculation using the exact raw data.
No test item could be detected in any trap from the experiments at 60 °C. Thus, the vapour pressure was calculated based on the smallest calibration solution measured during the respective HPLC run to be < 3.4 x 10-5 Pa at 60 °C.
Extrapolation to 25 °C was not possible. As no test item could be detected in any trap, the concentration was below the limit of quantification as well as below the limit of detection. Thus, the vapour pressure of LCA08042 is far below 10-5 Pa at 25 °C. The result of an additional calculation using Vapor Pressure Estimations (software MPBPWIN v1.41) was 5.89 x 10-7 Pa (calculated for 25 °C).
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