Registration Dossier
Registration Dossier
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EC number: 485-320-2 | CAS number: 221667-31-8
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: OECD 105 (Flask method)
- Principles of method if other than guideline:
- The solubility of the test item has been determined at 20 °C in the organic solvents ethanol, n-hexane, toluene, dichloromethane, acetone, ethylacetate and dimethyl sulfoxide based on Guideline 92/69/EEC, appendix A.6 (Flask method) and OECD-Guideline 105 (Flask method).
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- HESSISCHES MINISTERIUM FÜR UMWELT, LANDWIRTSCHAFT UND FORSTEN, Wiesbaden, Germany
- Medium:
- ethanol
- Solubility:
- 0.47 g/L
- Temp.:
- 20 °C
- Medium:
- other: n-hexane
- Solubility:
- < 0.001 g/L
- Temp.:
- 20 °C
- Medium:
- toluene
- Solubility:
- 0.047 g/L
- Temp.:
- 20 °C
- Medium:
- other: dichloromethane
- Solubility:
- 3.5 g/L
- Temp.:
- 20 °C
- Medium:
- acetone
- Solubility:
- 3.1 g/L
- Temp.:
- 20 °C
- Medium:
- ethyl acetate
- Solubility:
- 0.51 g/L
- Temp.:
- 20 °C
- Medium:
- DMSO
- Solubility:
- 200 - 300 g/L
- Temp.:
- 20 °C
Reference
Description of key information
Solubility at 20°C
Ethanol 0.47 g/L
n-Hexane < 0.001 g/L
Toluene 0.047 g/L
Dichloromethane 3.5 g/L
Acetone 3.1 g/L
Ethylacetate 0.51 g/L
Dimethyl sulfoxide 200 -300 g/L
(OECD 105, Flask method)
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
