Registration Dossier
Registration Dossier
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EC number: 605-539-0 | CAS number: 169115-74-6
Dissociation constant
Administrative data
Link to relevant study record(s)
Description of key information
The dissociation constants for 1-amino-2-propanol are estimated to be pKa1 of 9.19 and pKa2 of 12.92.
The dissociation constants for ethylene glycol are estimated to be pKa1 of 14.13 and pKa2 of 15.85.
The dissociation constants for 2-hydroxypropylcarbamic acid are estimated to be pKa1 of -1.55, pKa2 of 5.52, pKa3 of 14.99 and pKa4 of 18.16.
Key value for chemical safety assessment
Additional information
In general, dissociation constant would be determined experimentally. However, the substance consists of two ionic compounds which may only be analyzed with NMR and this is not applicable in this case. Therefore, QSAR estimations are assumed to be appropriate to fulfill the information requirements.
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