Registration Dossier
Registration Dossier
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EC number: 617-708-6 | CAS number: 85390-94-9
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
ZK 92136 did not show a mutagenic potential in a bacterial reverse mutation assay (Ames test in S. typhimurim strains TA 1535, TA 100, TA 1537, TA 1538 and TA98) when tested up to the cytotoxic (1 mg/plate) and precipitating (0.5 mg/plate) dose levels in the absense or presence of extrinsic metabolic activation (liver S9 mix from Aroclor 1254 -treated rats).
Short description of key information:
Gene mutation (bacterial reverse mutation assay / Ames test, GLP, OECD TG471): negative with and without metabolic activation
[Schering AG, Report No. X242 -draft-, 1997-08-26]
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Based on the results there is no classification required according to Directive 67/548/EEC and Regulation (EC) 1272/2008 (CLP).
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