Registration Dossier
Registration Dossier
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EC number: 918-139-9 | CAS number: 1228577-90-9
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 21 day-NOEC in a OECD 211 guideline study is ≥ 10 mg/l (nominal) for all mortality and the 21 day-EC10 is 2.5 mg/l (nominal) for reproduction.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.5 mg/L
Additional information
Chronic toxicity to invertebrates has been investigated in a reproduction test with Daphnia magna following the EU Method C.20 and OECD guideline 211 using semi-static exposure. No mortality was observed at the maximum concentration test (10 mg/l) and the NOEC reported as ≥ 10 mg/l (nominal) for mortality, however, for reproduction the 21 day EC10 value was reported as 2.5 mg/l (nominal). Exposure concentrations were verified by mean of HPLC-MSD and were ranging between 92.3 -100 per cent of the nominal values in the freshly prepared media and from 84.5 -100.9 per cent of nominal values in the media after 48 hours or 72 hours of exposure, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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