Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 615-229-7 | CAS number: 70969-57-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Reference
Description of key information
The hazard assessment is based on the data currently available. New studies with the registered substance and/or other member substances of the polyol esters category will be conducted in the future. The finalised studies will be included in the technical dossier as soon as they become available and the hazard assessment will be re-evaluated accordingly.
Key value for chemical safety assessment
Additional information
The hazard assessment is based on the data currently available. New studies with the registered substance and/or other member substances of the polyol esters category will be conducted in the future. The finalised studies will be included in the technical dossier as soon as they become available and the hazard assessment will be re-evaluated accordingly.
Experimental data on the toxicity of Octadecanoic acid, ester with 2,2'-[oxybis(methylene)]bis[2- (hydroxymethyl)-1,3-propanediol] (CAS 70969-57-2) to aquatic algae is not available. According to Regulation (EC) No 1907/2006, column 2, 9.1.2., short-term toxicity testing with aquatic algae does not need to be conducted if there are mitigating factors indicating that aquatic toxicity is unlikely to occur for instance if the substance is highly insoluble in water or the substance is unlikely to cross biological membranes. Octadecanoic acid, ester with 2,2'-[oxybis(methylene)]bis[2- (hydroxymethyl)-1,3-propanediol] (CAS 70969-57-2) is poorly soluble in water (< 1.7E-4 mg/L) and has a high molecular weight (1853.05 g/mol) indicating that a crossing biological membranes is unlikely. Based on the available read-across studies on aquatic toxicity with the structurally related source substance Fatty acids, C16-18 and C18-unsatd., hexaesters with dipentaerythritol (CAS 68604-38-6) effects to algae are not expected up to the limit of water solubility. Short-term toxicity testing with fish (Danio rerio) determined no acute toxicity of the substance up to the limit of water solubility (LL50 (96 h)> 100 mg/L). The lack of aquatic toxicity was confirmed by a long-term toxicity study on survival and reproduction of Daphnia magna. Mortality or a significant effect on the number of produced offspring was not observed (NOEC (21 d) ≥ 100 mg/L). Thus toxic effects of the substance to aquatic algae are not expected within the range of water solubility (WS < 1.7E-4 mg/L) and therefore toxicity testing on aquatic algae is not proposed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
