Registration Dossier
Registration Dossier
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EC number: 911-351-2 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
One reliable key study is available on the potassium salt of the registered reaction mass. The limit test shows no toxicity up to the highest concentration tested and therefore the LC50 for freshwater fish is higher than 100 mg/L.
Key value for chemical safety assessment
Additional information
One reliable key study is available on freshwater fish (Danio rerio) for the potassium salt of the registered reaction mass. The reaction mass IBAP and its potassium salt have high water solubility and their behavior in water and biological systems is dominated by their ionization. The main assumption is that the potassium cation is not significant in respect of the toxicological effect on aquatic organisms which are expected to be related to the IBAP. In experimental dilute aqueous conditions at environmental pH (5-9), the salt will be completely dissociated and will not behave differently to the parent acid, at identical concentration of the particular speciated form present.
The short term toxicity to fish was studied in a static limit test according to OECD TG No. 203 and Test Method C.1 from Commission Regulation (EC) No. 440/2008 under GLP. No mortality was recorded at the highest test concentration of 100 mg/L (based on nominal) after 96 hours of exposure of fish to the test item. The 96h LC50 was determined above 100 mg/L.
The results on effects are expressed in nominal concentration of test item because the analytical measurement based on phosphate show that it was stable among the study. For the purpose of risk assessment, PBT/vPvB assessment and classification and labeling, the concentration was not corrected for the target substance because the molecular weight of potassium was assessed to be negligible compared to the molecular weight of the other constituents of the reaction mass.
No data is available on marine fish species.
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