Registration Dossier
Registration Dossier
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EC number: 910-349-9 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018-03-20
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Key result
- Water solubility:
- >= 0.024 - <= 70 µg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 500 µg/L
- Incubation duration:
- >= 1 - <= 17 d
- Temp.:
- 20 °C
- pH:
- > 6.1 - < 6.3
- Conclusions:
- The water solubility of the test item was determined to be in range of 0.024 µg/L (based on Titanium) and 70 µg/L (based on Lanthanum) at 20 °C.
Reference
Description of key information
The water solubility of the test item was determined to be in range of 0.024 µg/L (based on Titanium) and 70 µg/L (based on Lanthanum) at 20 °C.
Key value for chemical safety assessment
- Water solubility:
- 0.024 µg/L
- at the temperature of:
- 20 °C
Additional information
The water solubility will be determined according to OECD 105 using the column elution method with ICP analysis. The water solubility of the test item was estimated to be in range of 0.024 µg/L (based on Titanium oxide) and 70 µg/L (based on Lanthanum oxide) at 20 °C. These data are based on the published data on titanium dioxide and lanthanum oxide. The study was initiated before 31 March 2018 but was not completed by the CRO in due time to complete the registration dossier. The study record will be updated as soon as the results will become available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
