Registration Dossier
Registration Dossier
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EC number: 932-051-8 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
The reaction product constituent linear alkylbenzene sulfonate is readily absorbed by the gastrointestinal tract and rapidly metabolized and excreted with its metabolites primarily in the urine but also in the bile and feces. The substance does not bioaccumulate in the tissues.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
There are two published studies for linear alkybenzene sulfonate. In th first study, the absorption, distribution, metabolism and elimination of LAS (radioactively labeled with 35S) were studied in male Charles River rats. LAS was readily absorbed by the gastrointestinal tract and rapidly metabolized and excreted in the urine. In the second study, the disposition of radioactivity was studied in single and repeated oral or subcutaneous doses of [14C]LAS to rhesus monkeys. Results show that LAS is rapidly absorbed, then rapidly metabolized and excreted, primarily in the urine but also in the bile and feces. No accumulation or localization of radioactivity or change in elimination was observed. LAS does not bioaccumulate in tissues.
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