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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Description of key information

The safety assessment according to Annex 1 does not indicate the need to investigate further the effects on aquatic organisms. Therefore no chronic fish testing is considered to be required.

Key value for chemical safety assessment

Additional information

A further refinement of the effect assessment may be considered necessary based on the outcome of the chemical safety assessment. Based on the currently available data the safety assessment according to Annex 1 does not indicate the need to investigate further the effects on aquatic organisms. In addition, fish are in general less sensitive to cationic surfactants when compared to algae and daphnia. The data on acute toxicity which is available for algae (river water), daphnia and fish with EC50s of 0.16, 0.31 and 0.13 indicates that the toxicity is in the same range for all organisms. It should be noted that the EC50 for algae is determined in natural river water due which a mitigation of about a factor of 5 is expected. The 21d EC50 for parental daphnids is 240 µg/L. Algae are based on this data considered to be the most sensitive species. For the calculation of the PNECaquatic bulkit is therefore considered unlikely that fish toxicity will be critical for diamine ethoxylates. Hence any additional toxicity testing with fish will not add scientific value to the ecotoxicity profile of the diamine ethoxylates other than for obtaining a lower assessment factor. It is therefore concluded that for scientific reasons and in accordance to REACH legislation further testing on fish has to be avoided for reasons of animal welfare. This means that it is proposed to waive the long term fish unless a further refinement of the effect assessment is considered necessary based on the outcome of the chemical safety assessment.

A safety factor of 50 is considered to be applicable for the derivation of the PNECaquatic, bulkof the diamine ethoxylates.