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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
no
Type of method:
flask method
Key result
Water solubility:
> 560 g/L
Temp.:
20 °C
pH:
6.3
Remarks on result:
other: The pH value of a 2:1 (water:test sample) solution was 6.3.

With 2.6 g of test item being mixed into 2 mL of water, a gel with a total weight of approximately 4.6 g has been formed. This is equivalent to 56 % (w/w) of test item in solution/gel.

 

As the density of the water will significantly increase with addition of the test item, it can be concluded that water solubility is about 560 g/L, resulting in a gel.

 

Due to the fact, that the formation of the gel is a continuous process and no discrete point can be identified at which dissolution in water switches to gelling, the water solubility can be approximated to > 560 g/L.

 

The water solubility of Reaction products of ricinoleic acid with 2-aminoethanol and maleic acid and sodium hydrogensulfite is greater than 500 g/L. The test sample is miscible with water in any proportion. With increasing amount of test item a gel is formed.

 

The water solubility was determined at 20 °C. The pH value of a 2:1 (water:test sample) solution was 6.3.

Conclusions:
Very soluble (> 10000 mg/L)
Executive summary:

In the non GLP Klimisch 1 key study from Frischmann (2012), the water solubility of Reaction products of ricinoleic acid with 2-aminoethanol and maleic acid and sodium hydrogensulfite was determined according to OECD 105 and EU method A.6. The water solubility was determined to be >560 g/L at 20°C.

The results of this study are considered relevant and reliable for the risk assessment.

Description of key information

Water solubility (20°C): > 560 g/L

Key value for chemical safety assessment

Water solubility:
560 g/L
at the temperature of:
20 °C

Additional information

In the non GLP Klimisch 1 key study from Frischmann (2012), the water solubility of Reaction products of ricinoleic acid with 2-aminoethanol and maleic acid and sodium hydrogensulfite was determined according to OECD 105 and EU method A.6. The water solubility was determined to be >560 g/L at 20°C.

The results of this study are considered relevant and reliable for the risk assessment.