1,6-Naphthyridine-3-carboxylic acid, 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-, 2-cyanoethyl ester

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)

Deviations:

no

GLP compliance:

no

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

other: test substance burned for about 6 seconds within the starting segment; no propagation was observed

The test substance melted when approached by the ignition flame and burned for about 6 seconds within the starting segment. No propagation was observed. Thus, no further testing was required.

Interpretation of results:

not classified based on GHS criteria

Conclusions:

CN-Ethyl-TH-naphthyridinon can be classified as a not readily combustible solid when tested according to UN-MTC Procedure N.1.

Executive summary:

The test was performed as stipulated in UN test procedure ‘Recommendations on the Transport of Dangerous Goods - Manual of Tests and Criteria’ (UN-MTC), Part III, sub-section 33.2.1.4.1, Test N.1 ‘Test method for readily combustible solids’. The substance in its delivery state was measured. CN-Ethyl-TH-naphthyridinon melted when approached by the ignition flame and did not burn up. No further testing was required. Therefore, the substance can be classified as a not readily combustible solid when tested according to UN-MTC Procedure N.1.

Reference 2

Endpoint:

pyrophoric solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied

Reference 3

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the organic substance does not contain metals or metalloids and hence, the classification procedure does not need to be applied

Description of key information

1. Flammability: CN-ethyl-TH-naphthyridinon can be classified as a not readily combustible solid when tested according to UN-MTC Procedure N.1.

2. Pyrophoric properties: CN-ethyl-TH-naphthyridinon did not deliver indications of pyrophoric properties during the realization of other tests. The determination according to UN-MTC Procedure N.2 is not necessary.

3. Contact with water: A review of the structure suggests that there are no chemical groups present that would imply pyrophoric properties or flammability on contact with water. A review of handling and used implies no pyrophoric properties or flammability on contact with water. Testing according to UN Procedure N.5 is not necessary.

Key value for chemical safety assessment

Flammability:

not classified