Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
9 Novembre 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The study was conducted according to an internationally recognised method, and under GLP. No deviation was reported. Test substance is adequately specified. Therefore full validation applies.
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
Commission Regulation (EC) No 761/2009 of 23. July 2009, published on 24. Aug. 2009
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
GLP certificate (inspected on 13 to 14 Octher 2014 / signed on 8 April 2015)
Type of method:
static method
Key result
Temp.:
20 °C
Vapour pressure:
359 Pa
Key result
Temp.:
25 °C
Vapour pressure:
486 Pa

The calculation results are presented in the following table:

Table 4.6/1.- Calculated values for 1/T and log P

n

Temperature T

Pressure P

Temperature T

1/T

log P

 

°C

hPa

K

1/K

log Pa

1

20.0

3.6

293.15

0.00341122

2.5563

2

28.8

5.3

301.95

0.00331181

2.7243

3

38.0

10.7

311.15

0.00321388

3.0294

4

47.0

17.0

320.15

0.00312354

3.2304

5

55.9

23.1

329.05

0.0030905

3.3636

6

48.0

19.2

321.15

0.00311381

3.2833

7

39.0

11.3

312.15

0.003120359

3.0531

8

30.0

6.1

303.15

0.00329870

2.7853

9

20.8

4.0

293.95

0.00340194

2.6021

10

14.7

2.6

287.85

0.00347403

2.4150

linear regression :

y = -2296.63268 x + 10.3893623

r = -0.994847802

r² = 0.9897 (> 0.95)

Using the equations below, vapour pressures at ambient temperature were calculated.

P(20 °C) = 10B * (1/293.15) + A 

P(25 °C) = 10B * (1/298.15) + A

Table 4.6/2.- Calculated Values for vapour pressure

Parameter

Value

Unit

Vapour Pressure (20 °C)

359

Pa

Vapour Pressure (25 °C)

486

Pa

The vapour pressure of the test item was measured using the static method as described in EU method A.4. Ten pairs temperature/vapour pressure were used to calculate a regression from which vapour pressure at ambient temperature could be estimated. From the measured values, the vapour pressure of the test item was calculated as 359 Pa at 20.0 °C and 486 Pa at 25 °C. The values of the heating and cooling down phase showed very good correspondence.

Therefore, the result of the study is considered valid.

Conclusions:
The vapor pressure of the test substance has been determined to be 359 Pa at 20 °C and 486 Pa at 25 °C (interpolation).
These values represent the components with the highest vapour pressure.
Executive summary:

The vapour pressure of test item was measured using the static method as described in EU method A.4 and OECD 104. Ten pairs temperature/vapour pressure were used to calculate a regression in a temperature range of 14.7 – 55.9 °C,from which vapour pressure at ambient temperature could be estimated.

From the measured values, the vapour pressure of the test itemwas calculated as 359 Pa at 20 °C and 486 Pa at 25 °C.

These values represent the components with the highest vapour pressure.

Description of key information

The vapour pressure of the test item was calculated as 359 Pa at 20 °C and 486 Pa at 25 °C (interpolation).

These values represent the components with the highest vapour pressure.

Key value for chemical safety assessment

Vapour pressure:
486 Pa
at the temperature of:
25 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available.

Therefore, it is considered as a key study, and the result can be retained as key data for purpose of CSA.

Note that the result obtained on this kind of substance should be largely influence by small amounts of volatile constituents and these values don't represent the major part of the substance. Therefore the result should be considered with caution when used for subsequent assessment (worst case).