Quaternary ammonium compounds, N,N,N'-tris(hydroxyethyl)-N,N'-dimethyl-N'-C16-18 (even numbered) and C18 unsatd., alkyltrimethylenedi-, bis(Me sulfates) (salts)

Guidance on Safe Use

First-aid measures

Description of first aid measures:

Protection of first-aiders:  No action shall be taken involving any personal risk or without suitable training. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation.

Eye contact: Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Continue to rinse for at least 10 minutes. Get medical attention.

Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous to the person

providing aid to give mouth-to-mouth resuscitation. Get medical attention if adverse health effects persist or are severe. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.

Skin contact: Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Continue to rinse for at least 10 minutes. Get medical attention. Wash clothing before reuse. Clean shoes thoroughly before reuse.

Ingestion: Wash out mouth with water. Remove dentures if any. Remove victim to fresh air and keep at rest in a position comfortable for breathing. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Get medical attention if adverse health effects persist or are severe. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.

Most important symptoms and effects, both acute and delayed:

Potential acute health effects:

Eye contact: Causes serious eye irritation.

Inhalation: No known significant effects or critical hazards.

Skin contact: Causes skin irritation.

Ingestion: Irritating to mouth, throat and stomach.

Over-exposure signs/symptoms:

Eye contact: Adverse symptoms may include the following: pain or irritation, watering and redness

Inhalation: No specific data.

Skin contact: Adverse symptoms may include the following: irritation and redness

Ingestion: No specific data.

Indication of any immediate medical attention and special treatment needed:

Notes to physician: Treat symptomatically. Contact poison treatment specialist immediately if large quantities have been ingested or inhaled.

Specific treatments: No specific treatment.

Fire-fighting measures

Extinguishing media:

Suitable extinguishing media: Use an extinguishing agent suitable for the surrounding fire.

Unsuitable extinguishing media: None known.

Special hazards arising from the substance or mixture:

Hazards from the substance or mixture: In a fire or if heated, a pressure increase will occur and the container may burst. This material is toxic to aquatic life with long lasting effects. Fire water contaminated with this material must be contained and prevented from being discharged to any waterway, sewer or drain.

Hazardous combustion products: Decomposition products may include the following materials: carbon dioxide and carbon monoxide.

Advice for firefighters:

Special precautions for fire-fighters: Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

Special protective equipment for fire-fighters: Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode. Clothing for fire-fighters (including helmets, protective boots and gloves) conforming to European standard EN 469 will provide a basic level of protection for chemical incidents.

Accidental release measures

Personal precautions, protective equipment and emergency procedures:

For non-emergency personnel: No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment.

For emergency responders: If specialised clothing is required to deal with the spillage, take note of any information in Section 8 on suitable and unsuitable materials. See also the information in "For non-emergency personnel".

Environmental precautions: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Water polluting material. May be harmful to the environment if released in large quantities. Collect spillage.

Methods and materials for containment and cleaning up:

Small spill: Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble. Alternatively, or if water-insoluble, absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a

licensed waste disposal contractor.

Large spill: Stop leak if without risk. Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash spillages into an effluent treatment plant or proceed as follows. Contain and

collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations. Dispose of via a licensed waste disposal contractor. Contaminated absorbent material may pose the same hazard as the spilled product.

Handling and storage

The information in this section contains generic advice and guidance. The list of Identified Uses should be consulted for any available use-specific information provided in the Exposure Scenario(s).

Precautions for safe handling:

Protective measures: Put on appropriate personal protective equipment. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist. Avoid release to the environment. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container.

Advice on general occupational hygiene: Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

Conditions for safe storage, including any incompatibilities: Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Seveso II Directive - Reporting thresholds (in tonnes):

Seveso II Directive: This product is controlled under the Seveso II Directive.

Category                                                                                   Notification and MAPP threshold                                                  Safety report threshold

E2: Hazardous to the aquatic environment - Chronic 2       200                                                                                      500

C9ii: Toxic for the environment                     200                                   500

Specific end use(s):

Recommendations: Not available.

Industrial sector specific solutions: Not available.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

UN3082

Shipping information

Proper shipping name and description:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S (Quaternary ammonium compound)

Chemical name:

Quaternary ammonium compound 2-methylpentane-2,4-diol

Language:

English

Labels:

9

Special provisions / remarks

Special provisions:

274, 335, 601, 375

Remarks:

Hazard identification number: 90
Limited quantity: LQ7
Tunnel code: (E)

Inland waterway transport (UN RTDG/ADN(R))

UN number:

UN3082

Shipping information

Proper shipping name and description:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S (Quaternary ammonium compound)

Chemical name:

Quaternary ammonium compound 2-methylpentane-2,4-diol

Language:

English

Labels:

9

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

UN3082

Shipping information

Proper shipping name and description:

Environmentally hazardous substance, liquid, n.o.s. (Quaternary ammonium compound). Marine pollutant (Fatty amine derivative)

Chemical name:

Quaternary ammonium compound 2-methylpentane-2,4-diol

Labels:

9

Special provisions / remarks

Remarks:

The marine pollutant mark is not required when transported in sizes of ≤5 L or ≤5 kg.

Air transport (UN RTDG/ICAO/IATA)

UN number:

UN3082

Shipping information

Proper shipping name and description:

ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S (Quaternary ammonium compound)

Chemical name:

Quaternary ammonium compound 2-methylpentane-2,4-diol

Labels:

9

Special provisions / remarks

Remarks:

The environmentally hazardous substance mark is not required when transported in sizes of ≤5 L or ≤5 kg.

Passenger and Cargo Aircraft:
Quantity limitation: 450 L
Packaging instructions: 964

Cargo Aircraft Only
Quantity limitation: 450 L
Packaging instructions: 964

Limited Quantities Passenger Aircraft
Quantity limitation: 30 L
Packaging instructions: Y964

Special provisions: A97, A158, A197

SpecialProvisions

Exposure controls / personal protection

The information in this section contains generic advice and guidance. Information is provided based on typical anticipated uses of the product. Additional measures might be required for bulk handling or other uses that could significantly increase worker or exposure or environmental releases.

Control parameters:

Occupational exposure limits:

Product/ingredient name                                                         Exposure limit values

Europe

No exposure limit value known.

Germany                                   MAK-Werte Liste (Germany, 7/2015).

2-methylpentane-2,4-diol                            PEAK: 98 mg/m³, 4 times per shift, 15 minutes.

                                  PEAK: 20 ppm, 4 times per shift, 15 minutes.

                                  TWA: 49 mg/m³ 8 hours.

                                  TWA: 10 ppm 8 hours.

Spain

2-methylpentane-2,4-diol                            INSHT (Spain, 1/2015).

                                  STEL: 123 mg/m³ 15 minutes.

                                  STEL: 25 ppm 15 minutes.

Recommended monitoring procedures: If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to determine the effectiveness of the ventilation or other control measures and/or the necessity to use respiratory protective equipment. Reference should be made to monitoring standards, such as the following: European Standard EN 689 (Workplace atmospheres - Guidance for the assessment of exposure by inhalation to chemical agents for comparison with limit values and measurement strategy) European Standard EN 14042 (Workplace atmospheres - Guide for the application and use of procedures for the assessment of exposure to chemical and biological agents) European Standard EN 482 (Workplace atmospheres - General requirements for the performance of procedures for the measurement of chemical agents) Reference to national guidance documents for methods for the determination of hazardous substances will also be required.

DNELs/DMELs: No DNELs/DMELs available.

PNECs: No PNECs available.

Exposure controls:

Appropriate engineering controls: Good general ventilation should be sufficient to control worker exposure to airborne contaminants.

Individual protection measures:

Hygiene measures: Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location.

Eye/face protection: Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. If contact is possible, the following protection should be worn, unless the assessment indicates a higher degree of protection: chemical splash goggles. Recommended: Splash goggles.,Safety glasses with side shields.

Skin protection:

Hand protection: Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. Considering the parameters specified by the glove manufacturer, check during use that the gloves are still retaining their protective properties. It should be noted that the time to breakthrough for any glove material may be different for different glove manufacturers. In the case of mixtures, consisting of

several substances, the protection time of the gloves cannot be accurately estimated. > 8 hours (breakthrough time): disposable vinyl

Body protection: Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. Recommended: Lab coat.,overall.

Other skin protection: Appropriate footwear and any additional skin protection measures should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product.

Recommended: neoprene

Respiratory protection: Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator.

Environmental exposure controls: Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

Remark: The penetration-time of the recommended gloves depends not only on the material. Also other factors may have influence on the penetration-time, as their thickness or the specific use or conditions (temperature). In any case, certificate materials (for

example following EN 374) should be selected. Please ask your supplier, if the gloves are suitable for the intended use.

Stability and reactivity

Reactivity: No specific test data related to reactivity available for this product or its ingredients.

Chemical stability: The product is stable.

Possibility of hazardous reactions: Under normal conditions of storage and use, hazardous reactions will not occur.

Conditions to avoid: No specific data.

Incompatible materials: No specific data.

Hazardous decomposition products: Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Disposal considerations

The information in this section contains generic advice and guidance. The list of Identified Uses should be consulted for any available use-specific information provided in the Exposure Scenario(s).

Waste treatment methods:

Product:

Methods of disposal: The generation of waste should be avoided or minimized wherever possible. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Waste should not be disposed of untreated to the sewer unless fully compliant with the requirements of all authorities with jurisdiction.

Hazardous waste: The classification of the product may meet the criteria for a hazardous waste.

Packaging:

Methods of disposal: The generation of waste should be avoided or minimized wherever possible. Waste packaging should be recycled. Incineration or landfill should only be considered when recycling is not feasible.

Special precautions: This material and its container must be disposed of in a safe way. Care should be taken when handling emptied containers that have not been cleaned or rinsed out. Empty containers or liners may retain some product residues. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.