Triglycerides, C16 and C18 (unsaturated)

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Batch No.of test material: 151124012
- Expiration date of the lot/batch: 01 March 2020
- Purity test date: Not reported

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Ambient
- Stability under test conditions: Stable under normal conditions.

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: None

Boiling pt.:

> 340 °C

Atm. press.:

1 013 mBar

Decomposition:

yes

Decomp. temp.:

ca. 340 °C

In the test using the Siwoloboff method the sample was observed to darken significantly by the time the temperature had reached 397°C. Bubbles were formed during the test but a consistent stream was not observed until after the test item had significantly darkened in appearance at 397°C.

Based on these observations, a DSC profile was generated to confirm thermal decomposition. The onset of decomposition at approximately 340°C was observed. The test item was initially described as yellow liquid and the material had turned into an amber crystalline melt during the DSC analysis at a heating rate of10°C/minute.

Conclusions:

The boiling temperature of triglycerides, C16 and C18 (unsaturated) could not be determined as the test item decomposed at temperatures above approximately 340°C.

Executive summary:

A study to determine boiling point of the test item, triglycerides, C16 and C18 (unsaturated), was conducted according to OECD 103 and EC A.2 guidelines. The boiling temperature was initially assessed by the Siwoloboff method using a calibrated digital melting point apparatus. Due to visual signs of decomposition, the test item was also assessed by differential scanning calorimetry (DSC).

The boiling temperature of the test item was not determinable as the test item decomposed at temperatures above approximately 340°C.

The study was conducted according to standard guidelines and is GLP-compliant and therefore is considered as reliable without restrictions.

Description of key information

The boiling temperature of the test item was not determinable as decomposition of test item was observed at temperatures above approximately 340°C.

Additional information

The boiling point study with triglycerides, C16 and C18 (unsaturated) was conducted according to OECD 103 and EC A.2 guidelines (Dunning 2019). The boiling temperature was initially assessed by the Siwoloboff method using a calibrated digital melting point apparatus. Due to visual signs of decomposition, the test item was also assessed by differential scanning calorimetry (DSC).

The study is a GLP compliant, guideline experimental study and is fully acceptable for assessment of this endpoint.