Registration Dossier
Registration Dossier
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EC number: 701-310-5 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
2,2’-oxydiethanol, ethoxylated and propoxylated (>1<4.5 EO and >1<4.5 PO) is an essentially non-volatile liquid at room temperature (vapor pressure 0.000386 hPa at 20°C), fully miscible with water and with a log P of (<0.3 at 25°C). There are no experimental studies on the toxicokinetics of 2,2`-oxydiethanol, ethoxylated and propoxylated (>1<4.5 EO and >1<4.5 PO). The information on the toxicokinetics of 2,2’-oxydiethanol, ethoxylated and propoxylated (>1<4.5 EO and >1<4.5 PO) is based on the information for 2,2`-oxydiethanol and propane-1,2 -diol and oligomers of propane-1,2 -diol.
The toxicokinetics of 2,2’-oxydiethanol and of propane-1,2-diol and its propoxylated oligomers have been examined in Illing and Barrat (2007 revised 2009). 2,2’-oxydiethanol, ethoxylated and propoxylated (>1<4.5 EO and >1<4.5 PO) can be reliably included into this read-across.
Propane-1, 2-diol is both a core substance (initiator) and a repeating unit. The information on the toxicokinetics of 2,2’-oxydipropanol, ethoxylated and propoxylated (>1<4.5 mol EO and >1<4.5 mol PO) (the NLP polyol) is based on the information for ethane-1,2-diol and its dimer (2,2’-oxydiethanol) and trimer and propane-1,2-diol and its dimer (1 mol propoxylated propane-1,2-diol) and trimer (2 mol propoxylated propane-1,2-diol). Propoxylated side chains are considered to be representatiove for ethoxylated and/or ethoxylated and propoxylated side chains. Oxydiethanol has two hydroxy groups, thus oligomers are considered to be core substances with chains of between one and three repeating units. Commercial material contains a range of ethoxylated and/or propoxylated oxydiethanols.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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