Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Guidance on Safe Use
Guidance on Safe Use
Administrative data
First-aid measures
Inhalation:
Move to fresh air. Call a physician if symptoms develop or persist.
Skin contact:
Wash off with soap and plenty of water. If skin irritation or rash occurs: Get medical advice/attention. Get medical advice/attention if you feel unwell. Wash contaminated clothing before reuse.
Eye contact:
Do not rub eyes. Immediately flush eyes with plenty of water for at least 15 minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical attention immediately.
Ingestion:
Rinse mouth. Call a physician or poison control centre immediately. Only induce vomiting at the
instruction of medical personnel. Never give anything by mouth to an unconsious person.
Move to fresh air. Call a physician if symptoms develop or persist.
Skin contact:
Wash off with soap and plenty of water. If skin irritation or rash occurs: Get medical advice/attention. Get medical advice/attention if you feel unwell. Wash contaminated clothing before reuse.
Eye contact:
Do not rub eyes. Immediately flush eyes with plenty of water for at least 15 minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical attention immediately.
Ingestion:
Rinse mouth. Call a physician or poison control centre immediately. Only induce vomiting at the
instruction of medical personnel. Never give anything by mouth to an unconsious person.
Fire-fighting measures
Extinguishing media:
Suitable extinguishing media: Water fog. Foam. Dry chemical powder. Carbon dioxide (CO2). Apply extinguishing media carefully to avoid creating airborne dust.
Unsuitable extinguishing media: Do not use water jet as an extinguisher, as this will spread the fire.
Special hazards arising from the substance or mixture:
Fire may produce irritating, corrosive and/or toxic gases. High concentration of airborne dust may form explosive mixture with air.
Advice for firefighters:
Self-contained breathing apparatus and full protective clothing must be worn in case of fire.
In case of fire and/or explosion do not breathe fumes. Move containers from fire area if you can do so without risk.
Suitable extinguishing media: Water fog. Foam. Dry chemical powder. Carbon dioxide (CO2). Apply extinguishing media carefully to avoid creating airborne dust.
Unsuitable extinguishing media: Do not use water jet as an extinguisher, as this will spread the fire.
Special hazards arising from the substance or mixture:
Fire may produce irritating, corrosive and/or toxic gases. High concentration of airborne dust may form explosive mixture with air.
Advice for firefighters:
Self-contained breathing apparatus and full protective clothing must be worn in case of fire.
In case of fire and/or explosion do not breathe fumes. Move containers from fire area if you can do so without risk.
Accidental release measures
Personal precautions, protective equipment and emergency procedures
For non-emergency personnel: Keep unnecessary personnel away. Local authorities should be advised if significant spillages cannot be contained.
For emergency responders: Keep unnecessary personnel away. Wear appropriate protective equipment and clothing during clean-up. Ensure adequate ventilation. ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Ventilate the contaminated area. Avoid the generation of dusts during clean-up. Do not get in eyes, on skin, or on clothing. Do not breathe dust. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.
Environmental precautions: Avoid discharge into drains, water courses or onto the ground.
Methods and material for containment and cleaning up:
Ensure adequate ventilation. Wear appropriate protective equipment and clothing during clean-up.
Eliminate all ignition sources (no smoking, flares, sparks, or flames in immediate area). Avoid the generation of dusts during clean-up. Avoid release to the environment.
Large Spills: Stop the flow of material, if this is without risk. Take precautionary measures against static discharge. Ground container and transfer equipment to eliminate static electric sparks. Use a non-combustible material like vermiculite, sand or earth to soak up the product and place into a container for later disposal. Clean surface thoroughly to remove residual contamination.
Small Spills: Wipe up with absorbent material (e.g. cloth, fleece). Clean surface thoroughly to remove residual contamination.
Never return spills to original containers for re-use.
For non-emergency personnel: Keep unnecessary personnel away. Local authorities should be advised if significant spillages cannot be contained.
For emergency responders: Keep unnecessary personnel away. Wear appropriate protective equipment and clothing during clean-up. Ensure adequate ventilation. ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Ventilate the contaminated area. Avoid the generation of dusts during clean-up. Do not get in eyes, on skin, or on clothing. Do not breathe dust. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.
Environmental precautions: Avoid discharge into drains, water courses or onto the ground.
Methods and material for containment and cleaning up:
Ensure adequate ventilation. Wear appropriate protective equipment and clothing during clean-up.
Eliminate all ignition sources (no smoking, flares, sparks, or flames in immediate area). Avoid the generation of dusts during clean-up. Avoid release to the environment.
Large Spills: Stop the flow of material, if this is without risk. Take precautionary measures against static discharge. Ground container and transfer equipment to eliminate static electric sparks. Use a non-combustible material like vermiculite, sand or earth to soak up the product and place into a container for later disposal. Clean surface thoroughly to remove residual contamination.
Small Spills: Wipe up with absorbent material (e.g. cloth, fleece). Clean surface thoroughly to remove residual contamination.
Never return spills to original containers for re-use.
Handling and storage
Precautions for safe handling:
Use this product with adequate ventilation. Minimise dust generation and accumulation. Avoid significant deposits of material, especially on horizontal surfaces, which may become airborne and form combustible dust clouds and may contribute to secondary explosions. Routine housekeeping should be instituted to ensure that dusts do not accumulate on surfaces. Dry powders can build static electricity charges when subjected to the friction of transfer and mixing operations. Provide adequate precautions, such as electrical grounding and bonding, or inert atmospheres. Do not handle, store or open near an open flame, sources of heat or sources of ignition. Protect material from direct sunlight. Provide appropriate exhaust ventilation at places where dust is formed. Wear personal protective equipment. Do not get in eyes, on skin, or on clothing. Do not breathe dust. Avoid prolonged exposure. Observe good industrial hygiene practices. When using, do not eat, drink or smoke. Wash thoroughly after handling. Wash contaminated clothing before reuse. Avoid release to the environment.
Conditions for safe storage, including any incompatibilities:
Keep containers tightly closed in a dry, cool and well-ventilated place. Keep away from heat and sources of ignition. This material can accumulate static charge which may cause spark and become an ignition source. Prevent electrostatic charge build-up by using common bonding and grounding techniques. Do not store in direct sunlight. Store away from incompatible materials.
Use this product with adequate ventilation. Minimise dust generation and accumulation. Avoid significant deposits of material, especially on horizontal surfaces, which may become airborne and form combustible dust clouds and may contribute to secondary explosions. Routine housekeeping should be instituted to ensure that dusts do not accumulate on surfaces. Dry powders can build static electricity charges when subjected to the friction of transfer and mixing operations. Provide adequate precautions, such as electrical grounding and bonding, or inert atmospheres. Do not handle, store or open near an open flame, sources of heat or sources of ignition. Protect material from direct sunlight. Provide appropriate exhaust ventilation at places where dust is formed. Wear personal protective equipment. Do not get in eyes, on skin, or on clothing. Do not breathe dust. Avoid prolonged exposure. Observe good industrial hygiene practices. When using, do not eat, drink or smoke. Wash thoroughly after handling. Wash contaminated clothing before reuse. Avoid release to the environment.
Conditions for safe storage, including any incompatibilities:
Keep containers tightly closed in a dry, cool and well-ventilated place. Keep away from heat and sources of ignition. This material can accumulate static charge which may cause spark and become an ignition source. Prevent electrostatic charge build-up by using common bonding and grounding techniques. Do not store in direct sunlight. Store away from incompatible materials.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- Not regulated as dangerous goods.
Shippingopen allclose all
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- Not regulated as dangerous goods.
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- Not regulated as dangerous goods.
Shippingopen allclose all
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- Not regulated as dangerous goods.
Shippingopen allclose all
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Appropriate engineering controls:
Provide adequate general and local exhaust ventilation. Good general ventilation (typically 10 air
changes per hour) should be used. Ventilation rates should be matched to conditions. If applicable, use process enclosures, local exhaust ventilation, or other engineering controls to
maintain airborne levels below recommended exposure limits. If exposure limits have not been
established, maintain airborne levels to an acceptable level.
Individual protection measures, such as personal protective equipment:
General information: Use personal protective equipment as required. Personal protection equipment should be chosen according to the CEN standards and in discussion with the supplier of the personal protective equipment.
Eye/face protection: Wear safety glasses with side shields (or goggles).
Skin protection:
Wear appropriate chemical resistant gloves.
Wear suitable protective clothing. Use protective clothing (uniforms, lab coats, disposable coveralls, etc.) in both production and laboratory areas. Impervious protective clothing is recommended if skin contact with drug product is possible and for bulk processing operations.
Respiratory protection:
In case of insufficient ventilation, wear suitable respiratory equipment. Respiratory protection should be provided in instances where exposure to dust, mists, aerosols or vapors are likely. If the applicable Occupational Exposure Limit (OEL) is exceeded, wear an appropriate respirator with a protection factor sufficient to control exposures to below the OEL.
Thermal hazards: Wear appropriate thermal protective clothing, when necessary.
Provide adequate general and local exhaust ventilation. Good general ventilation (typically 10 air
changes per hour) should be used. Ventilation rates should be matched to conditions. If applicable, use process enclosures, local exhaust ventilation, or other engineering controls to
maintain airborne levels below recommended exposure limits. If exposure limits have not been
established, maintain airborne levels to an acceptable level.
Individual protection measures, such as personal protective equipment:
General information: Use personal protective equipment as required. Personal protection equipment should be chosen according to the CEN standards and in discussion with the supplier of the personal protective equipment.
Eye/face protection: Wear safety glasses with side shields (or goggles).
Skin protection:
Wear appropriate chemical resistant gloves.
Wear suitable protective clothing. Use protective clothing (uniforms, lab coats, disposable coveralls, etc.) in both production and laboratory areas. Impervious protective clothing is recommended if skin contact with drug product is possible and for bulk processing operations.
Respiratory protection:
In case of insufficient ventilation, wear suitable respiratory equipment. Respiratory protection should be provided in instances where exposure to dust, mists, aerosols or vapors are likely. If the applicable Occupational Exposure Limit (OEL) is exceeded, wear an appropriate respirator with a protection factor sufficient to control exposures to below the OEL.
Thermal hazards: Wear appropriate thermal protective clothing, when necessary.
Stability and reactivity
Reactivity: The product is stable and non-reactive under normal conditions of use, storage and transport.
Chemical stability: Material is stable under normal conditions.
Possibility of hazardous reactions: No dangerous reaction known under conditions of normal use.
Conditions to avoid: Contact with incompatible materials. Sunlight. High temperatures. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. Avoid conditions which create dust.
Incompatible materials: Strong oxidising agents.
Hazardous decomposition products: Irritating and/or toxic fumes and gases may be emitted upon the product's decomposition
Chemical stability: Material is stable under normal conditions.
Possibility of hazardous reactions: No dangerous reaction known under conditions of normal use.
Conditions to avoid: Contact with incompatible materials. Sunlight. High temperatures. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. Avoid conditions which create dust.
Incompatible materials: Strong oxidising agents.
Hazardous decomposition products: Irritating and/or toxic fumes and gases may be emitted upon the product's decomposition
Disposal considerations
Avoid release to the environment. Do not discharge into drains, water courses or onto the ground.
Do not dispose of waste into sewer. Do not contaminate ponds, waterways or ditches with chemical or used container. Considering the relevant known environmental and human health hazards of the material, review and implement appropriate technical and procedural waste water
and waste disposal measures to prevent occupational exposure and environmental release. It is
recommended that waste minimization be practiced. The best available technology should be utilized to prevent environmental releases. This may include destructive techniques for waste and
wastewater. Dispose of contents/container in accordance with local/regional/national/international regulations.
Do not dispose of waste into sewer. Do not contaminate ponds, waterways or ditches with chemical or used container. Considering the relevant known environmental and human health hazards of the material, review and implement appropriate technical and procedural waste water
and waste disposal measures to prevent occupational exposure and environmental release. It is
recommended that waste minimization be practiced. The best available technology should be utilized to prevent environmental releases. This may include destructive techniques for waste and
wastewater. Dispose of contents/container in accordance with local/regional/national/international regulations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
