Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
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Substance data
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Details
2-Propenoic acid, 2-methyl-, 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl ester
424-240-4 96478-09-0 Active Full Individual ≥ 1 to < 10 tonnes 26-10-2012 View substance registered dossier
2-Propenoic acid, 2-methyl-, 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl ester
424-240-4 96478-09-0 Active Full Joint ≥ 1 tonnes 08-03-2018 View substance registered dossier
2-Propenoic acid, 2-methyl-, 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl ester
424-240-4 96478-09-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
N-[2-(3-carbamoyl-4-hydroxyphenyl)-2-oxoethyl]-N-(4-phenylbut-2-yl)ammonium chloride
700-288-4 96441-14-4 Active Intermediate Joint Intermediate use only 04-05-2018 View substance registered dossier
2-Propenoic acid, 2-chloro-, 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl ester
801-260-5 96383-55-0 Active Full Joint ≥ 10 to < 100 tonnes 01-06-2020 View substance registered dossier
trans-4-phenyl-L-proline
SQ 27,616
416-020-1 96314-26-0 Active Intermediate Individual Intermediate use only 13-04-2017 View substance registered dossier
trans-4-phenyl-L-proline
SQ 27,616
416-020-1 96314-26-0 Active NONS Joint Tonnage data confidential 09-12-2013 View substance registered dossier
5α-androst-2-en-17-one
213-517-3 963-75-7 Active Intermediate Joint Intermediate use only 19-03-2020 View substance registered dossier
Demoxepam
213-515-2 963-39-3 Active Intermediate Joint Intermediate use only 24-07-2017 View substance registered dossier
3H-1,2,4-Triazol-3-one, 4-amino-2,4-dihydro-5-(1-methylethyl)-
689-404-1 96240-10-7 Cease Manufacture Intermediate Individual Cease manufacture 25-08-2011 View substance registered dossier
3H-1,2,4-Triazol-3-one, 4-amino-2,4-dihydro-5-(1-methylethyl)-
689-404-1 96240-10-7 Active Intermediate Joint Intermediate use only 11-06-2021 View substance registered dossier
Phenol, dodecyl-, branched, sulfurized
306-115-5 96152-43-1 Active Full Joint ≥ 10 to < 100 tonnes 21-05-2018 View substance registered dossier
9-Octadecenoic acid (Z)-, isooctyl ester, reaction products with glycerol trioleate and sulfur
306-111-3 96152-40-8 Active Full Joint ≥ 100 to < 1 000 tonnes 23-05-2013 View substance registered dossier
N-[3-[[4-(diethylamino)-2-methylphenyl]imino]-6-oxo-1,4-cyclohexadienyl]acetamide
414-740-0 96141-86-5 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
Potassium (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetate
213-510-5 961-69-3 Active Intermediate Joint Intermediate use only 04-05-2018 View substance registered dossier
(2R)-3-(acetyloxy)-2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]propyl (2S)-2-amino-3-methylbutanoate hydrochloride
691-736-7 960495-42-5 Active Intermediate Joint Intermediate use only 01-06-2016 View substance registered dossier
Solvate of (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol with 2-butyne-1, 4-diol (1:1)
619-496-0 960404-59-5 Active Full Individual ≥ 10 to < 100 tonnes 14-03-2017 View substance registered dossier
methyl 1-(3-chloropyridin-2-yl)-3-(hydroxymethyl)-1H-pyrazole-5-carboxylate
937-132-1 960316-73-8 Active Intermediate Individual Intermediate use only 02-09-2016 View substance registered dossier
ethyl 2-acetyl-4-methyltridec-2-enoate
816-455-0 960253-23-0 Active Full Joint ≥ 10 to < 100 tonnes 24-02-2021 View substance registered dossier
4-chloro-3-nitrobenzoic acid
202-550-9 96-99-1 Active Intermediate Joint Intermediate use only 20-04-2017 View substance registered dossier
3-nitro-p-toluic acid
202-549-3 96-98-0 Active Intermediate Joint Intermediate use only 28-04-2014 View substance registered dossier
5-nitrosalicylic acid
202-548-8 96-97-9 Active Full Joint ≥ 1 to < 10 tonnes 04-08-2018 View substance registered dossier
2-nitro-p-anisidine
202-547-2 96-96-8 Active Full Joint ≥ 0 to < 10 tonnes 27-02-2018 View substance registered dossier
3-amino-4-hydroxy-5-nitrobenzenesulphonic acid
202-546-7 96-93-5 Active Full Joint ≥ 0 to < 10 tonnes 03-05-2018 View substance registered dossier
2-amino-4,6-dinitrophenol
202-544-6 96-91-3 Active Full Joint ≥ 1 to < 10 tonnes 06-06-2016 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Covance Clinical Development SA 104 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain Spain Active 2-Propenoic acid, 2-methyl-, 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl ester 424-240-4 96478-09-0 2012 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 2-Propenoic acid, 2-methyl-, 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl ester 424-240-4 96478-09-0 2017; 2018 View substance registered dossier
Johnson & Johnson Vision Care Ireland Unlimited Company (UC) National Technology Park Plassey none Limerick Co Limerick Ireland Ireland Active 2-Propenoic acid, 2-methyl-, 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl ester 424-240-4 96478-09-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active 2-Propenoic acid, 2-methyl-, 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethyl ester 424-240-4 96478-09-0 - View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active N-[2-(3-carbamoyl-4-hydroxyphenyl)-2-oxoethyl]-N-(4-phenylbut-2-yl)ammonium chloride 700-288-4 96441-14-4 - View substance registered dossier
Cosma S.p.A. Via Colleoni 15/17 24040 Ciserano (BG) Italy Italy Active N-[2-(3-carbamoyl-4-hydroxyphenyl)-2-oxoethyl]-N-(4-phenylbut-2-yl)ammonium chloride 700-288-4 96441-14-4 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active N-[2-(3-carbamoyl-4-hydroxyphenyl)-2-oxoethyl]-N-(4-phenylbut-2-yl)ammonium chloride 700-288-4 96441-14-4 2010; 2017; 2018 View substance registered dossier
SCAS Europe S.A./N.V. Leonardo Da Vincilaan 19 B-1831 Diegem Belgium Belgium Active 2-Propenoic acid, 2-chloro-, 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl ester 801-260-5 96383-55-0 2014; 2020 View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active trans-4-phenyl-L-proline 416-020-1 96314-26-0 - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture trans-4-phenyl-L-proline 416-020-1 96314-26-0 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active trans-4-phenyl-L-proline 416-020-1 96314-26-0 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 5α-androst-2-en-17-one 213-517-3 963-75-7 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Demoxepam 213-515-2 963-39-3 2017 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active Demoxepam 213-515-2 963-39-3 2017 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture 3H-1,2,4-Triazol-3-one, 4-amino-2,4-dihydro-5-(1-methylethyl)- 689-404-1 96240-10-7 2017 View substance registered dossier
KISCHEMICALS LLC Gyártelep 3792 Sajóbábony Hungary Hungary Active 3H-1,2,4-Triazol-3-one, 4-amino-2,4-dihydro-5-(1-methylethyl)- 689-404-1 96240-10-7 - View substance registered dossier
Domus Chemicals S.p.A v. Mazzini 1 24066 Pedrengo Bergamo Italy Italy Active Phenol, dodecyl-, branched, sulfurized 306-115-5 96152-43-1 2018 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active 9-Octadecenoic acid (Z)-, isooctyl ester, reaction products with glycerol trioleate and sulfur 306-111-3 96152-40-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active N-[3-[[4-(diethylamino)-2-methylphenyl]imino]-6-oxo-1,4-cyclohexadienyl]acetamide 414-740-0 96141-86-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active N-[3-[[4-(diethylamino)-2-methylphenyl]imino]-6-oxo-1,4-cyclohexadienyl]acetamide 414-740-0 96141-86-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active N-[3-[[4-(diethylamino)-2-methylphenyl]imino]-6-oxo-1,4-cyclohexadienyl]acetamide 414-740-0 96141-86-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active N-[3-[[4-(diethylamino)-2-methylphenyl]imino]-6-oxo-1,4-cyclohexadienyl]acetamide 414-740-0 96141-86-5 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active Potassium (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetate 213-510-5 961-69-3 - View substance registered dossier
ANTIBIOTICOS DE LEON S.L. Avda. Antibióticos, 59 - 61 24009 León Spain Spain Active Potassium (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetate 213-510-5 961-69-3 - View substance registered dossier
Deretil S.A. Villaricos, s/n 04618 Cuevas del Almanzora Almeria Spain Spain Active Potassium (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetate 213-510-5 961-69-3 - View substance registered dossier
Sandoz Industrial Products SA Ctra. Granollers - Cardedeu C-251, Km 4 08520 Les Franqueses del Vallés Spain Spain Active Potassium (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetate 213-510-5 961-69-3 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20090 RODANO Milano Italy Italy No longer Valid (2R)-3-(acetyloxy)-2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]propyl (2S)-2-amino-3-methylbutanoate hydrochloride 691-736-7 960495-42-5 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (2R)-3-(acetyloxy)-2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]propyl (2S)-2-amino-3-methylbutanoate hydrochloride 691-736-7 960495-42-5 2012; 2014; 2016 View substance registered dossier
SK BIOTEK IRELAND LIMITED Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland Ireland Active Solvate of (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol with 2-butyne-1, 4-diol (1:1) 619-496-0 960404-59-5 2014; 2017 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active methyl 1-(3-chloropyridin-2-yl)-3-(hydroxymethyl)-1H-pyrazole-5-carboxylate 937-132-1 960316-73-8 2016 View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active ethyl 2-acetyl-4-methyltridec-2-enoate 816-455-0 960253-23-0 2021 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Cease Manufacture 4-chloro-3-nitrobenzoic acid 202-550-9 96-99-1 2017 View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 4-chloro-3-nitrobenzoic acid 202-550-9 96-99-1 2017 View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 3-nitro-p-toluic acid 202-549-3 96-98-0 - View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Cease Manufacture 3-nitro-p-toluic acid 202-549-3 96-98-0 2019 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 5-nitrosalicylic acid 202-548-8 96-97-9 2013; 2015; 2018 View substance registered dossier
ALCHEMIE INDUSTRIES CHEMICAL SPAIN, S.L. Atlantida, 21 1º3º 08930 Sant Adria de Besos Spain Spain Active 2-nitro-p-anisidine 202-547-2 96-96-8 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active 2-nitro-p-anisidine 202-547-2 96-96-8 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 2-nitro-p-anisidine 202-547-2 96-96-8 - View substance registered dossier
Univar Solutions GmbH Hinsbecker Löh 10c 45257 Essen Germany Germany Active 2-nitro-p-anisidine 202-547-2 96-96-8 - View substance registered dossier
Vlisco Netherlands BV Binnen Parallelweg 27 5701 PH Helmond NB Netherlands Netherlands Active 2-nitro-p-anisidine 202-547-2 96-96-8 - View substance registered dossier
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active 3-amino-4-hydroxy-5-nitrobenzenesulphonic acid 202-546-7 96-93-5 2012; 2013 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 3-amino-4-hydroxy-5-nitrobenzenesulphonic acid 202-546-7 96-93-5 - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 3-amino-4-hydroxy-5-nitrobenzenesulphonic acid 202-546-7 96-93-5 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 2-amino-4,6-dinitrophenol 202-544-6 96-91-3 - View substance registered dossier

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