Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.

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Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 9,101 - 9,150 of 26,865 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
Anthranilic acid	204-287-5	118-92-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	21-09-2012	View substance registered dossier
Anthranilic acid	204-287-5	118-92-3	Active	Intermediate	Individual	Intermediate use only	20-08-2013	View substance registered dossier
2'-hydroxyacetophenone	204-288-0	118-93-4	Active	Intermediate	Joint	Intermediate use only	11-05-2023	View substance registered dossier
2,4,6-trinitrotoluene	204-289-6	118-96-7	Active	Full	Joint	≥ 1 000 to < 10 000 tonnes	23-11-2022	View substance registered dossier
(αR,α'R,2R,2'S)- 2H- 1-Benzopyran-2-methanol, α,α'-[[(phenylmethyl)imino]-bis(methylene)]-bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1)	927-046-2	1180001-17-5	Active	Intermediate	Individual	Intermediate use only	17-10-2014	View substance registered dossier
(αR,α'R,2R,2'S)- 2H- 1-Benzopyran-2-methanol, α,α'-[[(phenylmethyl)imino]-bis(methylene)]-bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1)	927-046-2	1180001-17-5	Active	Intermediate	Joint	Intermediate use only	29-05-2018	View substance registered dossier
2-hydroxy-5-(1-hydroxy-2-((4-phenylbutan-2-yl)amino)ethyl)benzamide acetate	810-097-9	1180001-45-9	Active	Intermediate	Joint	Intermediate use only	26-07-2018	View substance registered dossier
5-[(4-ethylpiperazin-1-yl)methyl]pyridine-2-amine	806-688-6	1180132-17-5	Active	Intermediate	Joint	Intermediate use only	16-10-2019	View substance registered dossier
2-(1-butyl-3,5-dioxo-2-phenyl-(1,2,4)-triazolidin-4-yl)-4,4-dimethyl-3-oxo-N-(2-methoxy-5-(2-(dodecyl-1-sulfonyl))propionylamino)-phenyl)-pentanamide N 89	418-060-5	118020-93-2	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
2-hydroxy-N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide	601-503-3	118026-14-5	Active	Intermediate	Joint	Intermediate use only	30-05-2018	View substance registered dossier
(2R,3S,4R,5R,7R,9R,10R,11S,12S,13R)-10-((4-Dimethylamino-3-hydroxy-6-methyltetrahydropyran-2-yl)oxy)-2-ethyl-3,4,12-trihydroxy-9-methoxy-3,5,7,9,11,13-hexamethyl-6,14-dioxo-1-oxacyclotetradecane	433-820-6	118058-74-5	Active	NONS	Joint	Tonnage data confidential	15-12-2008	View substance registered dossier
(E)-5-(3-bromophenyl)pent-4-enoic acid	881-198-3	1180670-58-9	Active	Intermediate	Joint	Intermediate use only	22-04-2022	View substance registered dossier
2-Chlormethyl-8-(1,1-dimethylethyl)-1,4-dioxaspiro[4.5]decan	601-507-5	118135-28-7	Active	Intermediate	Individual	Intermediate use only	23-03-2017	View substance registered dossier
2,4-bis[2,2'-[2-(N,N-dimethylamino)ethyloxycarbonyl]phenylazo]-1,3-dihydroxybenzene-dihydrochloride BASISCH GELB 8511	407-010-8	118208-02-9	Active	NONS	Joint	Tonnage data confidential	22-08-2011	View substance registered dossier
2-Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, acetate (1:1)	813-916-8	1182346-22-0	Active	Intermediate	Joint	Intermediate use only	11-12-2017	View substance registered dossier
5-(Hydroxymethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	838-943-2	1182358-83-3	Active	Intermediate	Joint	Intermediate use only	29-05-2019	View substance registered dossier
3-((R)-amino-1,2,3,4-tetrahydrocarbazol-9-yl)propanoic acid	923-144-4	1182722-58-2	Active	Full	Joint	≥ 1 to < 10 tonnes	04-11-2015	View substance registered dossier
Carbonic acid, 5-amino-2,4-bis(1,1-dimethylethyl)phenyl methyl este	696-357-0	1182822-31-6	Active	Intermediate	Joint	Intermediate use only	03-06-2015	View substance registered dossier
trans-5-butyl-2-(3',3'',4'',5''-tetrafluoro-1,1':4',1''-terphenyl-4-yl)-1,3-dioxane	807-577-5	1182844-21-8	Active	Full	Joint	≥ 0 to < 10 tonnes	06-09-2019	View substance registered dossier
6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one CP-89,575	421-320-0	118289-55-7	Active	Intermediate	Joint	Intermediate use only	26-07-2021	View substance registered dossier
(3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile	828-107-5	118316-12-4	Active	Intermediate	Joint	Intermediate use only	05-09-2018	View substance registered dossier
1,3,7,9-tetratert-butyl-11-fluoro-5-methyl-5H-benzo[d][1,3,2]benzodioxaphosphocine	403-020-1	118337-09-0	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
Trimethylamine, N-oxide	214-675-6	1184-78-7	Active	Full	Joint	≥ 10 to < 100 tonnes	03-04-2023	View substance registered dossier
[2-(2-aminophenylsulfanyl)-phenyl]-[4-(2-hydroxyethyl)-piperazin-1-yl]methanone hydrochloride	807-584-3	1184176-84-8	Active	Intermediate	Individual	Intermediate use only	24-10-2017	View substance registered dossier
N-Acetyl-L-glutamic acid - 1-((7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanaminemonohydrate (1:1)	922-576-0	1184182-45-3	Active	Full	Joint	≥ 1 to < 10 tonnes	05-12-2018	View substance registered dossier
N-Acetyl-L-glutamic acid - 1-((7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanaminemonohydrate (1:1)	922-576-0	1184182-45-3	Cease Manufacture	Intermediate	Individual	Cease manufacture	07-05-2012	View substance registered dossier
2H-1-Benzopyran-2-methanol, a,a'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-, (aR,a'R,2R,2'S)-rel-	601-527-4	118457-14-0	Active	Intermediate	Joint	Intermediate use only	29-05-2018	View substance registered dossier
4-[(3,5-Dichlorobenzoyl)amino]-3-hydroxybenzoic acid	832-365-4	1184581-58-5	Active	Intermediate	Joint	Intermediate use only	24-01-2019	View substance registered dossier
N-(2-Benzoyl-4 Chlorophenyl)-2-Bromo-N-(Cyclopropylmethyl)-Acetamide	920-284-8	1184768-58-8	Active	Intermediate	Joint	Intermediate use only	29-08-2019	View substance registered dossier
2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	Active	Full	Joint	≥ 100 to < 1 000 tonnes	09-12-2022	View substance registered dossier
Trimethoxy(methyl)silane	214-685-0	1185-55-3	Active	Full	Joint	≥ 1 000 to < 10 000 tonnes	17-03-2023	View substance registered dossier
Trimethoxy(methyl)silane	214-685-0	1185-55-3	Active	Intermediate	Individual	Intermediate use only	13-06-2023	View substance registered dossier
Ammonium iron(III) citrate	214-686-6	1185-57-5	Active	Full	Joint	≥ 10 to < 100 tonnes	26-05-2021	View substance registered dossier
Ammonium iron(III) citrate	214-686-6	1185-57-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	01-05-2018	View substance registered dossier
Dibutylbis(dodecylthio)stannane	214-688-7	1185-81-5	Active	Full	Joint	≥ 1 to < 10 tonnes	12-04-2021	View substance registered dossier
1-(2-isopropyl-1,3-thiazol-4-yl)-N-methylmethanamine dihydrochloride	937-695-3	1185167-55-8	Active	Intermediate	Individual	Intermediate use only	31-07-2012	View substance registered dossier
8-[4-(4-methylphenyl)cyclohexyl]-1,4-Dioxaspiro[4.5]decane	801-233-8	1185257-39-9	Active	Intermediate	Joint	Intermediate use only	13-12-2017	View substance registered dossier
Silicic acid (H4SiO4), mixed 2-butoxyethyl and methyl tetraesters	418-360-6	1185356-03-9	Active	NONS	Individual	Tonnage data confidential	10-11-2008	View substance registered dossier
trans-2-Cyclododecenyl propanoic acid ethylester	601-534-2	118562-69-9	Active	Intermediate	Individual	Intermediate use only	27-02-2019	View substance registered dossier
2-cyclododecylpropan-1-ol HYDROXYAMBRAN	411-410-8	118562-73-5	Active	Full	Individual	≥ 1 to < 10 tonnes	11-02-2020	View substance registered dossier
2-cyclododecylpropan-1-ol HYDROXYAMBRAN	411-410-8	118562-73-5	No longer Valid	NONS	Individual	No longer valid	10-11-2008	View substance registered dossier
Reaction products of Benzoic acid, 2-[[4-chloro-6-[[8-hydroxy-3,6-disulfo-7-[(1-sulfo-2-naphthalenyl)azo]-1-naphthalenyl]amino]-1,3,5-triazin-2-yl]amino]-5-sulfo-, pentasodium salt and lithium chloride	943-083-7	118578-12-4	Active	Full	Individual	≥ 1 to < 10 tonnes	08-11-2018	View substance registered dossier
2-[4-N,N-bis-(β-methoxycarbonyl-ethyl)amino-2-methylphenylazo]-3-ethoxycarbonyl-5-nitrothiophene C.I. DISPERSE BLUE 356	400-460-6	118578-14-6	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
N,N-dimethylanilinium tetrakis(pentafluorophenyl)borate B1; N,N-DIMETHYLANILINUM TETRAKIS(PENTAFLUOROPHENYL)BORATE; TÉTRAKIS(PENTAFLUOROPHÉNYL)BORATE DE N,N-DIMÉTHYLANILINIUM	422-050-6	118612-00-3	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
7-[4-(3-diethylaminopropylamino)-6-(3-diethylammoniopropylamino)-1,3,5-triazin-2-ylamino]-4-hydroxy-3-(4-phenylazophenylazo)-naphthalene-2-sulfonate, acetic acid, lactic acid (2:1:1) CARTASOL RED K-2BN; RED 10 25 501	408-000-6	118658-98-3	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'-dipyridinium dichloride dihydrochloride CARTASOL GEEL M-GL CONC.; CARTASOL GELB M-GL FLÜSSIG (ZUBEREITUNG); CARTASOL GELB M-GL KONZ.; CARTASOL YELLOW M-GL CONC.; HM 2580	401-500-5	118658-99-4	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
A mixture of: disodium (6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)(1-(5-chloro-2-oxidophenylazo)-2-naphtholato)chromate(1-); trisodium bis(6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)chromate(1-) AZUL MARINHO 018112; BLEU MARINE 018112; NAVY 018112; NAVY BLUE 018112	405-665-4	118685-33-9	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
Sodium 5-N-butylbenzotriazole COBRATEC 435	404-450-2	118685-34-0	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
Sodium 5-N-butylbenzotriazole COBRATEC 435	404-450-2	118685-34-0	Active	Full	Joint	≥ 10 tonnes	13-10-2016	View substance registered dossier
Trifluoro(trifluoromethoxy)ethylene	214-703-7	1187-93-5	Active	Full	Joint	≥ 100 to < 1 000 tonnes	25-11-2022	View substance registered dossier

Showing 9,101 - 9,150 of 26,865 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
Intertek Deutschland GmbH CWBC	Stangenstr.1 70771 Leinfelden-Echterdingen Baden-Württemberg Germany	Germany	Cease Manufacture	Anthranilic acid	204-287-5	118-92-3	2019	View substance registered dossier
[Confidential]	-	-	-	Anthranilic acid	204-287-5	118-92-3	-	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(SINO-HIGH(CHINA) CO., LTD.)	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	2'-hydroxyacetophenone	204-288-0	118-93-4	-	View substance registered dossier
Symrise AG	Mühlenfeldstraße 1 37603 Holzminden Germany	Germany	Active	2'-hydroxyacetophenone	204-288-0	118-93-4	2022	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	2'-hydroxyacetophenone	204-288-0	118-93-4	2017	View substance registered dossier
ERREGIERRE SPA	Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy	Italy	Active	2'-hydroxyacetophenone	204-288-0	118-93-4	-	View substance registered dossier
VIA 2000 LTD	Vranya 68 1309 Sofia Bulgaria	Bulgaria	Active	2,4,6-trinitrotoluene	204-289-6	118-96-7	-	View substance registered dossier
REACH GLOBAL SERVICES S.A.	Rond Point Schuman, 6 B-1040 Brussels Belgium	Belgium	Active	2,4,6-trinitrotoluene	204-289-6	118-96-7	-	View substance registered dossier
MAXAMCORP INTERNATIONAL, S.L.	Avenida Partenon, 16 28042 Madrid Spain	Spain	Active	2,4,6-trinitrotoluene	204-289-6	118-96-7	2021	View substance registered dossier
STV GROUP a.s.	Žitná 45 11000 Praha1 Czech Republic	Czech Republic	Active	2,4,6-trinitrotoluene	204-289-6	118-96-7	-	View substance registered dossier
Nammo Vingåkersverken AB	Vingåkersverken 64392 Vingåker Sweden	Sweden	Active	2,4,6-trinitrotoluene	204-289-6	118-96-7	-	View substance registered dossier
OSTCHEM Germany GmbH	Erdmannstr. 10 22765 Hamburg Germany	Germany	Cease Manufacture	2,4,6-trinitrotoluene	204-289-6	118-96-7	2022	View substance registered dossier
TELA Ltd	4, Rozova dolina Str, suite 12 1421 Sofia sofia Bulgaria	Bulgaria	Active	2,4,6-trinitrotoluene	204-289-6	118-96-7	-	View substance registered dossier
EXPAL Systems, S.A.	Avda. Partenon, 16 28042 Madrid Madrid Spain	Spain	Active	2,4,6-trinitrotoluene	204-289-6	118-96-7	2022	View substance registered dossier
Karash invest LTD	10, Sazaklyatie str. 5300 Gabrovo Gabrovo Bulgaria	Bulgaria	Active	2,4,6-trinitrotoluene	204-289-6	118-96-7	2022	View substance registered dossier
Zakłady Chemiczne „NITRO-CHEM” S.A.	Theodora Wulffa 18 85-862 Bydgoszcz Poland	Poland	Active	2,4,6-trinitrotoluene	204-289-6	118-96-7	2012; 2013; 2014; 2015; 2020; 2021	View substance registered dossier
cordenpharma chenove	47, rue de Longvic 21300 Chenôve France	France	Active	(αR,α'R,2R,2'S)- 2H- 1-Benzopyran-2-methanol, α,α'-[[(phenylmethyl)imino]-bis(methylene)]-bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1)	927-046-2	1180001-17-5	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(αR,α'R,2R,2'S)- 2H- 1-Benzopyran-2-methanol, α,α'-[[(phenylmethyl)imino]-bis(methylene)]-bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1)	927-046-2	1180001-17-5	-	View substance registered dossier
PROCOS SpA	via Matteotti 249 28062 Cameri Piemonte Italy	Italy	Active	2-hydroxy-5-(1-hydroxy-2-((4-phenylbutan-2-yl)amino)ethyl)benzamide acetate	810-097-9	1180001-45-9	2015; 2018	View substance registered dossier
Eli Lilly Kinsale Limited	Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland	Ireland	Active	5-[(4-ethylpiperazin-1-yl)methyl]pyridine-2-amine	806-688-6	1180132-17-5	2017; 2019	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	Active	2-(1-butyl-3,5-dioxo-2-phenyl-(1,2,4)-triazolidin-4-yl)-4,4-dimethyl-3-oxo-N-(2-methoxy-5-(2-(dodecyl-1-sulfonyl))propionylamino)-phenyl)-pentanamide	418-060-5	118020-93-2	-	View substance registered dossier
FINORGA - MOURENX	avenue du lac 64150 MOURENX France	France	Active	2-hydroxy-N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide	601-503-3	118026-14-5	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	2-hydroxy-N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide	601-503-3	118026-14-5	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(2R,3S,4R,5R,7R,9R,10R,11S,12S,13R)-10-((4-Dimethylamino-3-hydroxy-6-methyltetrahydropyran-2-yl)oxy)-2-ethyl-3,4,12-trihydroxy-9-methoxy-3,5,7,9,11,13-hexamethyl-6,14-dioxo-1-oxacyclotetradecane	433-820-6	118058-74-5	-	View substance registered dossier
Sanofi Aventis Deutschland GmbH	Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany	Germany	Active	(2R,3S,4R,5R,7R,9R,10R,11S,12S,13R)-10-((4-Dimethylamino-3-hydroxy-6-methyltetrahydropyran-2-yl)oxy)-2-ethyl-3,4,12-trihydroxy-9-methoxy-3,5,7,9,11,13-hexamethyl-6,14-dioxo-1-oxacyclotetradecane	433-820-6	118058-74-5	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	(2R,3S,4R,5R,7R,9R,10R,11S,12S,13R)-10-((4-Dimethylamino-3-hydroxy-6-methyltetrahydropyran-2-yl)oxy)-2-ethyl-3,4,12-trihydroxy-9-methoxy-3,5,7,9,11,13-hexamethyl-6,14-dioxo-1-oxacyclotetradecane	433-820-6	118058-74-5	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	(E)-5-(3-bromophenyl)pent-4-enoic acid	881-198-3	1180670-58-9	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	2-Chlormethyl-8-(1,1-dimethylethyl)-1,4-dioxaspiro[4.5]decan	601-507-5	118135-28-7	2010; 2017	View substance registered dossier
Solenis Netherlands B.V.	Pesetastraat 62 2991 XT Barendrecht Netherlands	Netherlands	Active	2,4-bis[2,2'-[2-(N,N-dimethylamino)ethyloxycarbonyl]phenylazo]-1,3-dihydroxybenzene-dihydrochloride	407-010-8	118208-02-9	2011	View substance registered dossier
Archroma Germany GmbH	Kasteler Str. 45 65203 Wiesbaden Germany	Germany	Active	2,4-bis[2,2'-[2-(N,N-dimethylamino)ethyloxycarbonyl]phenylazo]-1,3-dihydroxybenzene-dihydrochloride	407-010-8	118208-02-9	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	Active	2,4-bis[2,2'-[2-(N,N-dimethylamino)ethyloxycarbonyl]phenylazo]-1,3-dihydroxybenzene-dihydrochloride	407-010-8	118208-02-9	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	2-Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, acetate (1:1)	813-916-8	1182346-22-0	2017	View substance registered dossier
MSD International GmbH (Ballydine Branch)	Ballydine - Kilsheelan 0 Clonmel Ireland	Ireland	Active	5-(Hydroxymethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	838-943-2	1182358-83-3	-	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	3-((R)-amino-1,2,3,4-tetrahydrocarbazol-9-yl)propanoic acid	923-144-4	1182722-58-2	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany	Germany	Active	3-((R)-amino-1,2,3,4-tetrahydrocarbazol-9-yl)propanoic acid	923-144-4	1182722-58-2	-	View substance registered dossier
Esteve Quimica, S.A.	Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain	Spain	Active	Carbonic acid, 5-amino-2,4-bis(1,1-dimethylethyl)phenyl methyl este	696-357-0	1182822-31-6	2015	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	trans-5-butyl-2-(3',3'',4'',5''-tetrafluoro-1,1':4',1''-terphenyl-4-yl)-1,3-dioxane	807-577-5	1182844-21-8	2019	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one	421-320-0	118289-55-7	-	View substance registered dossier
Upjohn Manufacturing Ireland Unlimited	Little Island T45 F627 Co. Cork Ireland	Ireland	Active	6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one	421-320-0	118289-55-7	2013; 2021	View substance registered dossier
Farmabios Spa	Via Pavia, 1 27027 Gropello Cairoli PV Italy	Italy	Active	(3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile	828-107-5	118316-12-4	-	View substance registered dossier
-	-	-	-	1,3,7,9-tetratert-butyl-11-fluoro-5-methyl-5H-benzo[d][1,3,2]benzodioxaphosphocine	403-020-1	118337-09-0	-	View substance registered dossier
COMPO Expert GmbH	Krögerweg 10 48155 Münster NRW Germany	Germany	Active	Trimethylamine, N-oxide	214-675-6	1184-78-7	-	View substance registered dossier
Plant Response, Inc. Sucursal en España.	C/Ciruelos s/n. Centro de Empresas. Campus UPM Montegancedo Pozuelo de Alarcón 28223 Madrid Spain	Spain	Active	Trimethylamine, N-oxide	214-675-6	1184-78-7	2019; 2023	View substance registered dossier
Fermion Oy	Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland	Finland	Active	[2-(2-aminophenylsulfanyl)-phenyl]-[4-(2-hydroxyethyl)-piperazin-1-yl]methanone hydrochloride	807-584-3	1184176-84-8	-	View substance registered dossier
LABORATORIOS SERVIER S.L.	RIO JARAMA 59 45007 TOLEDO Spain	Spain	Active	N-Acetyl-L-glutamic acid - 1-((7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanaminemonohydrate (1:1)	922-576-0	1184182-45-3	2018	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Cease Manufacture	N-Acetyl-L-glutamic acid - 1-((7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanaminemonohydrate (1:1)	922-576-0	1184182-45-3	2013	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	2H-1-Benzopyran-2-methanol, a,a'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-, (aR,a'R,2R,2'S)-rel-	601-527-4	118457-14-0	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X336 Ringaskiddy Cork Ireland	Ireland	Active	4-[(3,5-Dichlorobenzoyl)amino]-3-hydroxybenzoic acid	832-365-4	1184581-58-5	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	N-(2-Benzoyl-4 Chlorophenyl)-2-Bromo-N-(Cyclopropylmethyl)-Acetamide	920-284-8	1184768-58-8	-	View substance registered dossier
AVANTOR PERFORMANCE MATERIALS POLAND SPÓŁKA AKCYJNA	Sowińskiego 11 44-101 Gliwice Silesia Poland	Poland	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
Beckman Coulter GmbH	Europark Fichtenhain B13 47807 Krefeld Germany	Germany	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
SIGMA-ALDRICH CHIMIE SARL	80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France	France	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
SAFC Biosciences Limited	Smeaton Road, West Potway SP10 3LF Andover United Kingdom	United Kingdom	No longer Valid	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	2021	View substance registered dossier
Sigma-Aldrich Ireland Ltd	Vale Road . Arklow Co. Wicklow Ireland	Ireland	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
HH Compliance Ltd	Rubicon Centre C.I.T. Campus T12 Y275 Bishopstown Cork Ireland	Ireland	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	2020	View substance registered dossier
TÜV SÜD Iberia S.A.U.	Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain	Spain	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
Roche Diagnostics GmbH	Sandhoferstrasse 116 68305 Mannheim Germany	Germany	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	2020	View substance registered dossier
AppliChem GmbH	Ottoweg 4 64291 Darmstadt Hessen Germany	Germany	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
Sigma-Aldrich Company Limited	The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom	United Kingdom	No longer Valid	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	2021	View substance registered dossier
Acros Organics bv	Janssen Pharmaceuticalaan 3a B-2440 Geel Belgium	Belgium	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
TÜV SÜD Iberia, S.A.U.	Ronda Can Fatjo, 13 Parc Tecnologic del Valles 08290 Cerdanyola del Valles Barcelona Spain	Spain	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
Becton Dickinson Distribution Center NV	Laagstraat 57 9140 Temse Belgium	Belgium	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
Beckman Coulter France SAS	130, Avenue de Lattre de Tassigny 13009 Marseille France	France	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
Abbott Diagnostics GmbH	Max Planck Ring 2 D-65205 Delkenheim Hessen Germany	Germany	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
Abbott GmbH	Max Planck Ring 2 D-65205 Wiesbaden Germany	Germany	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
ANGUS CHEMIE OR1	Zeppelinstrasse 30 49479 Ibbenbueren Germany	Germany	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH	Riedstrasse 2 89555 Steinheim Germany	Germany	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
VWR International BV	Haasrode Researchpark 2020 3001 Leuven Belgium	Belgium	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
ANGUS CHEMIE GMBH	Zeppelinstr. 30 Postfach 4003 D-49479 Ibbenbueren-Uffeln Germany	Germany	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
Kirsch Pharma GmbH	Erzwäsche 2 38229 Salzgitter Germany	Germany	Active	2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride	214-684-5	1185-53-1	-	View substance registered dossier
Axalta Coating Systems Germany GmbH & Co. KG	Christbusch 25 42285 Wuppertal Germany	Germany	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	2023	View substance registered dossier
knoell Germany – OR – B11	Konrad-Zuse-Ring 25 68163 Mannheim Germany	Germany	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
BRB International B.V.	Europastraat 5 6014 CD Ittervoort Netherlands	Netherlands	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED	Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
NAM&NAM Europe GmbH	Am Kronberger Hang 2 65824 Schwalbach Germany	Germany	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
Dow Silicones Belgium SPRL OR-1	rue Jules Bordet Parc industriel C 7180 Seneffe Belgium	Belgium	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	2014; 2016; 2017; 2018; 2021; 2022	View substance registered dossier
Dow Silicones Belgium SPRL OR-2	Rue Jules Bordet Parc industriel C 7180 Seneffe Belgium	Belgium	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
Dow Silicones Belgium SPRL OR-3	Rue Jules Bordet Zone industrielle C 7180 Seneffe Belgium	Belgium	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
SCAS Europe S.A./N.V.	Leonardo Da Vincilaan 19 B-1831 Diegem Belgium	Belgium	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
knoell Germany – OR – B10	Konrad-Zuse-Ring 25 68163 Mannheim Germany	Germany	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
NAM & NAM Europe GmbH	Am Kronberger Hang 2 65824 Schwalbach Germany	Germany	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
Momentive Performance Materials Specialties Srl	Zona Industriale- Località Rivolta Del Re Termoli 86039 Termoli CB Italy	Italy	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	2019	View substance registered dossier
Shin-Etsu Silicones Europe BV	Bolderweg 32 1332 AV Almere Netherlands	Netherlands	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
B-Lands Consulting (811689-3)	OR of Hubei Bluesky New Materials Inc. 5 Place Robert Schuman - BP 1516 38025 Grenoble France France	France	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
REACH24H CONSULTING GROUP	Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland	Ireland	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
Wacker Chemie AG	Hanns-Seidel-Platz 4 81737 Muenchen Germany	Germany	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	2011; 2016; 2017; 2018; 2021	View substance registered dossier
Dow Silicones Belgium SPRL	Rue Jules Bordet Zone industrielle C 7180 Seneffe Belgium	Belgium	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
Momentive Performance Materials GmbH	Chempark, Building V7 PO 4502311119 51368 Leverkusen NRW Germany	Germany	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	2019	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	No longer Valid	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
Nitrochemie Aschau GmbH	Liebigstrasse 17 84544 Aschau am Inn Germany	Germany	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
Nouryon Surface Chemistry AB	Box 47067 40258 Göteborg Sweden	Sweden	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	2021	View substance registered dossier
CRCP GmbH	Am Römerhof 51 60486 Frankfurt am Main Germany	Germany	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Guangzhou Jinggui New Materials Co., Ltd.)	Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland	Ireland	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
Chemical Inspection & Regulation Service Limited	Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland	Ireland	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	-	View substance registered dossier
CHT Germany GmbH	Bismarckstr. 102 72072 Tuebingen Germany	Germany	Active	Trimethoxy(methyl)silane	214-685-0	1185-55-3	2023	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Active	Ammonium iron(III) citrate	214-686-6	1185-57-5	2018; 2019	View substance registered dossier
Dr. Paul Lohmann GmbH & Co. KGaA	Hauptstraße 2 31860 Emmerthal Germany	Germany	Active	Ammonium iron(III) citrate	214-686-6	1185-57-5	-	View substance registered dossier
METCO SRL	VIA GALILEI 4 40053 VALSAMOGGIA LOC. MONTEVEGLIO BOLOGNA Italy	Italy	Active	Ammonium iron(III) citrate	214-686-6	1185-57-5	-	View substance registered dossier
Global Life Sciences Solutions Austria GmbH & Co KG	Kremplstraße 5 4061 Pasching Austria	Austria	Active	Ammonium iron(III) citrate	214-686-6	1185-57-5	-	View substance registered dossier
Arcerion GmbH	Gabrielenstr. 15 80636 Muenchen Germany	Germany	Cease Manufacture	Ammonium iron(III) citrate	214-686-6	1185-57-5	2018	View substance registered dossier
Evonik Gorapur GmbH	Rudolf-Diesel-Strasse 3 19243 Wittenburg Germany	Germany	Cease Manufacture	Dibutylbis(dodecylthio)stannane	214-688-7	1185-81-5	2019	View substance registered dossier
Evonik Operations GmbH - ME01	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Cease Manufacture	Dibutylbis(dodecylthio)stannane	214-688-7	1185-81-5	2018	View substance registered dossier
Evonik Operations GmbH - E06	Rellinghauser Strasse 1-11 45128 Essen Germany	Germany	Active	Dibutylbis(dodecylthio)stannane	214-688-7	1185-81-5	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	Dibutylbis(dodecylthio)stannane	214-688-7	1185-81-5	2018	View substance registered dossier
Flamma S.p.a.	via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy	Italy	Active	1-(2-isopropyl-1,3-thiazol-4-yl)-N-methylmethanamine dihydrochloride	937-695-3	1185167-55-8	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	8-[4-(4-methylphenyl)cyclohexyl]-1,4-Dioxaspiro[4.5]decane	801-233-8	1185257-39-9	-	View substance registered dossier
-	-	-	-	Silicic acid (H4SiO4), mixed 2-butoxyethyl and methyl tetraesters	418-360-6	1185356-03-9	-	View substance registered dossier
Miltitz Aromatics GmbH	Chemiepark Bitterfeld-Wolfen Riechstoffstrasse 1 06803 Bitterfeld-Wolfen Germany	Germany	Active	trans-2-Cyclododecenyl propanoic acid ethylester	601-534-2	118562-69-9	2019	View substance registered dossier
Miltitz Aromatics GmbH	Chemiepark Bitterfeld-Wolfen Riechstoffstrasse 1 06803 Bitterfeld-Wolfen Germany	Germany	Active	2-cyclododecylpropan-1-ol	411-410-8	118562-73-5	2015; 2020	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	No longer Valid	2-cyclododecylpropan-1-ol	411-410-8	118562-73-5	2022	View substance registered dossier
Only representative (No publishable name)	-	-	Active	Reaction products of Benzoic acid, 2-[[4-chloro-6-[[8-hydroxy-3,6-disulfo-7-[(1-sulfo-2-naphthalenyl)azo]-1-naphthalenyl]amino]-1,3,5-triazin-2-yl]amino]-5-sulfo-, pentasodium salt and lithium chloride	943-083-7	118578-12-4	2018	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	2-[4-N,N-bis-(β-methoxycarbonyl-ethyl)amino-2-methylphenylazo]-3-ethoxycarbonyl-5-nitrothiophene	400-460-6	118578-14-6	-	View substance registered dossier
DyStar Colours Distribution GmbH	Am Prime-Parc 12 65479 Raunheim Germany	Germany	Cease Manufacture	2-[4-N,N-bis-(β-methoxycarbonyl-ethyl)amino-2-methylphenylazo]-3-ethoxycarbonyl-5-nitrothiophene	400-460-6	118578-14-6	2012	View substance registered dossier
-	-	-	-	N,N-dimethylanilinium tetrakis(pentafluorophenyl)borate	422-050-6	118612-00-3	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	7-[4-(3-diethylaminopropylamino)-6-(3-diethylammoniopropylamino)-1,3,5-triazin-2-ylamino]-4-hydroxy-3-(4-phenylazophenylazo)-naphthalene-2-sulfonate, acetic acid, lactic acid (2:1:1)	408-000-6	118658-98-3	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority.	-	-	Active	7-[4-(3-diethylaminopropylamino)-6-(3-diethylammoniopropylamino)-1,3,5-triazin-2-ylamino]-4-hydroxy-3-(4-phenylazophenylazo)-naphthalene-2-sulfonate, acetic acid, lactic acid (2:1:1)	408-000-6	118658-98-3	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Swedish competent national authority.	-	-	Active	7-[4-(3-diethylaminopropylamino)-6-(3-diethylammoniopropylamino)-1,3,5-triazin-2-ylamino]-4-hydroxy-3-(4-phenylazophenylazo)-naphthalene-2-sulfonate, acetic acid, lactic acid (2:1:1)	408-000-6	118658-98-3	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	7-[4-(3-diethylaminopropylamino)-6-(3-diethylammoniopropylamino)-1,3,5-triazin-2-ylamino]-4-hydroxy-3-(4-phenylazophenylazo)-naphthalene-2-sulfonate, acetic acid, lactic acid (2:1:1)	408-000-6	118658-98-3	-	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Active	7-[4-(3-diethylaminopropylamino)-6-(3-diethylammoniopropylamino)-1,3,5-triazin-2-ylamino]-4-hydroxy-3-(4-phenylazophenylazo)-naphthalene-2-sulfonate, acetic acid, lactic acid (2:1:1)	408-000-6	118658-98-3	-	View substance registered dossier
Archroma UK, Ltd	1 Bartholomew Lane EC2N 2AX London United Kingdom	United Kingdom	No longer Valid	7-[4-(3-diethylaminopropylamino)-6-(3-diethylammoniopropylamino)-1,3,5-triazin-2-ylamino]-4-hydroxy-3-(4-phenylazophenylazo)-naphthalene-2-sulfonate, acetic acid, lactic acid (2:1:1)	408-000-6	118658-98-3	2021	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority.	-	-	Active	7-[4-(3-diethylaminopropylamino)-6-(3-diethylammoniopropylamino)-1,3,5-triazin-2-ylamino]-4-hydroxy-3-(4-phenylazophenylazo)-naphthalene-2-sulfonate, acetic acid, lactic acid (2:1:1)	408-000-6	118658-98-3	-	View substance registered dossier
Archroma Germany GmbH	Kasteler Str. 45 65203 Wiesbaden Germany	Germany	Active	(methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'-dipyridinium dichloride dihydrochloride	401-500-5	118658-99-4	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	(methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'-dipyridinium dichloride dihydrochloride	401-500-5	118658-99-4	-	View substance registered dossier
Archroma UK, Ltd	1 Bartholomew Lane EC2N 2AX London United Kingdom	United Kingdom	No longer Valid	(methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'-dipyridinium dichloride dihydrochloride	401-500-5	118658-99-4	2021	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Active	(methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'-dipyridinium dichloride dihydrochloride	401-500-5	118658-99-4	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	(methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'-dipyridinium dichloride dihydrochloride	401-500-5	118658-99-4	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority.	-	-	Active	(methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1'-dipyridinium dichloride dihydrochloride	401-500-5	118658-99-4	-	View substance registered dossier
Archroma Germany GmbH	Kasteler Str. 45 65203 Wiesbaden Germany	Germany	Cease Manufacture	A mixture of: disodium (6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)(1-(5-chloro-2-oxidophenylazo)-2-naphtholato)chromate(1-); trisodium bis(6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)chromate(1-)	405-665-4	118685-33-9	2020	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	A mixture of: disodium (6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)(1-(5-chloro-2-oxidophenylazo)-2-naphtholato)chromate(1-); trisodium bis(6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)chromate(1-)	405-665-4	118685-33-9	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority.	-	-	Active	A mixture of: disodium (6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)(1-(5-chloro-2-oxidophenylazo)-2-naphtholato)chromate(1-); trisodium bis(6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)chromate(1-)	405-665-4	118685-33-9	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Portuguese competent national authority.	-	-	Active	A mixture of: disodium (6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)(1-(5-chloro-2-oxidophenylazo)-2-naphtholato)chromate(1-); trisodium bis(6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)chromate(1-)	405-665-4	118685-33-9	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	A mixture of: disodium (6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)(1-(5-chloro-2-oxidophenylazo)-2-naphtholato)chromate(1-); trisodium bis(6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)chromate(1-)	405-665-4	118685-33-9	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Swedish competent national authority.	-	-	Active	A mixture of: disodium (6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)(1-(5-chloro-2-oxidophenylazo)-2-naphtholato)chromate(1-); trisodium bis(6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)chromate(1-)	405-665-4	118685-33-9	-	View substance registered dossier
ARCHROMA IBÉRICA, S.L.	ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain	Spain	Cease Manufacture	A mixture of: disodium (6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)(1-(5-chloro-2-oxidophenylazo)-2-naphtholato)chromate(1-); trisodium bis(6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)chromate(1-)	405-665-4	118685-33-9	2020	View substance registered dossier
Archroma UK, Ltd	1 Bartholomew Lane EC2N 2AX London United Kingdom	United Kingdom	No longer Valid	A mixture of: disodium (6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)(1-(5-chloro-2-oxidophenylazo)-2-naphtholato)chromate(1-); trisodium bis(6-(4-anisidino)-3-sulfonato-2-(3,5-dinitro-2-oxidophenylazo)-1-naphtholato)chromate(1-)	405-665-4	118685-33-9	2021	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority.	-	-	Active	Sodium 5-N-butylbenzotriazole	404-450-2	118685-34-0	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority.	-	-	Active	Sodium 5-N-butylbenzotriazole	404-450-2	118685-34-0	-	View substance registered dossier
Veolia WTS France	Immeuble L'Aquarène 1 place Montgolfier 94417 SAINT-MAURICE CEDEX France	France	Active	Sodium 5-N-butylbenzotriazole	404-450-2	118685-34-0	2016	View substance registered dossier
SUEZ WATER TECHNOLOGIES & SOLUTIONS (UK) LIMITED PARTNERSHIP	HydroHouse - Newcombe Way Orton Southgate PE2 6SE Peterborough Cambridgeshire United Kingdom	United Kingdom	No longer Valid	Sodium 5-N-butylbenzotriazole	404-450-2	118685-34-0	2021	View substance registered dossier
Veolia Water Technologies & Solutions Belgium BVBA	Toekomstlaan 54 2200 Herentals Belgium	Belgium	Active	Sodium 5-N-butylbenzotriazole	404-450-2	118685-34-0	2016	View substance registered dossier
3M Belgium BVBA/SPRL (OR1)	Hermeslaan 7 1831 Diegem Belgium	Belgium	Active	Trifluoro(trifluoromethoxy)ethylene	214-703-7	1187-93-5	-	View substance registered dossier
Chemours Netherlands B.V.	Baanhoekweg 22 3313 LA Dordrecht Netherlands	Netherlands	Active	Trifluoro(trifluoromethoxy)ethylene	214-703-7	1187-93-5	2016; 2022	View substance registered dossier
[Confidential]	-	-	-	Trifluoro(trifluoromethoxy)ethylene	214-703-7	1187-93-5	-	View substance registered dossier
SCAS Europe S.A./N.V.	Leonardo Da Vincilaan 19 B-1831 Diegem Belgium	Belgium	Active	Trifluoro(trifluoromethoxy)ethylene	214-703-7	1187-93-5	-	View substance registered dossier
AGC Chemicals Europe, Ltd	World Trade Centre Zuidplein 80 1077XV Amsterdam Netherlands	Netherlands	Active	Trifluoro(trifluoromethoxy)ethylene	214-703-7	1187-93-5	-	View substance registered dossier
Dyneon GmbH	Industrieparkstrasse 1 84508 Burgkirchen a. d. Alz Germany	Germany	Active	Trifluoro(trifluoromethoxy)ethylene	214-703-7	1187-93-5	-	View substance registered dossier
Labcorp Development SA 160	Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5-5 Planta 28050 Madrid Spain	Spain	Active	Trifluoro(trifluoromethoxy)ethylene	214-703-7	1187-93-5	2020	View substance registered dossier
Solvay Specialty Polymers Italy S.p.A.	Viale Lombardia 20 20021 BOLLATE Italy	Italy	Active	Trifluoro(trifluoromethoxy)ethylene	214-703-7	1187-93-5	2016; 2021	View substance registered dossier

Showing 9,101 - 9,150 of 26,865 results.

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.