Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
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Details
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active Intermediate Joint Intermediate use only 25-07-2019 View substance registered dossier
4-[(5-{[(benzyloxy)carbonyl]amino}pentyl)(hydroxy)amino]-4-oxobutanoic acid
600-744-1 106410-46-2 Active Intermediate Joint Intermediate use only 07-10-2019 View substance registered dossier
4-[(E)-2-nitroethenyl]-1H-indole
634-890-2 49839-99-8 Active Intermediate Joint Intermediate use only 23-04-2018 View substance registered dossier
4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride
447-990-4 - Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid
429-790-9 137281-39-1 Active Intermediate Individual Intermediate use only 31-10-2017 View substance registered dossier
4-[2-(Cyclopropylmethoxy)ethyl]phenol
440-910-9 - Active Intermediate Joint Intermediate use only 12-10-2018 View substance registered dossier
4-[2-(diethylamino)ethoxy]benzophenone
212-348-2 796-77-0 Active Intermediate Joint Intermediate use only 13-10-2016 View substance registered dossier
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol
700-516-2 93413-62-8 Active Intermediate Individual Intermediate use only 17-04-2013 View substance registered dossier
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol
700-516-2 93413-62-8 Active Intermediate Joint Intermediate use only 07-04-2021 View substance registered dossier
4-[2-(methoxymethyl)-3-methyl-1-methylene-but-2-enyl]-1H-tetrazol-5-one
826-908-4 1472631-98-3 Active Intermediate Joint Intermediate use only 28-10-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
VALDEPHARM Parc Industriel d'Incarville CS10606 27106 Val de Reuil France France Active 4-[(5-{[(benzyloxy)carbonyl]amino}pentyl)(hydroxy)amino]-4-oxobutanoic acid 600-744-1 106410-46-2 2012 View substance registered dossier
Menadiona SL Pol Ind Mas Puigvert, Ctra Nacional II Km 680, 5 08389 Palafolls Barcelona Spain Spain Active 4-[(5-{[(benzyloxy)carbonyl]amino}pentyl)(hydroxy)amino]-4-oxobutanoic acid 600-744-1 106410-46-2 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active 4-[(5-{[(benzyloxy)carbonyl]amino}pentyl)(hydroxy)amino]-4-oxobutanoic acid 600-744-1 106410-46-2 - View substance registered dossier
URQUIMA S.A. AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain Spain Active 4-[(E)-2-nitroethenyl]-1H-indole 634-890-2 49839-99-8 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride 447-990-4 - 2019 View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active 4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid 429-790-9 137281-39-1 2010; 2012; 2013; 2017 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-[2-(Cyclopropylmethoxy)ethyl]phenol 440-910-9 - 2017 View substance registered dossier
FINORGA - MOURENX avenue du lac 64150 MOURENX France France Active 4-[2-(Cyclopropylmethoxy)ethyl]phenol 440-910-9 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 4-[2-(diethylamino)ethoxy]benzophenone 212-348-2 796-77-0 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol 700-516-2 93413-62-8 2013 View substance registered dossier
Medichem Manufacturing (Malta) Limited HF 61-Hal Far Industrial Estate BBG 3000 Hal Far Malta Malta Malta Active 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol 700-516-2 93413-62-8 - View substance registered dossier
[Confidential] - - - 4-[2-(methoxymethyl)-3-methyl-1-methylene-but-2-enyl]-1H-tetrazol-5-one 826-908-4 1472631-98-3 - View substance registered dossier

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