Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
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  • Consumer Uses
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  • Uses at industrial sites
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Details
Diethyl ethoxymethylenemalonate
201-725-7 87-13-8 Active Full Joint ≥ 0 to < 10 tonnes 15-01-2019 View substance registered dossier
Diethyl ethoxymethylenemalonate
201-725-7 87-13-8 Active Intermediate Joint Intermediate use only 29-03-2018 View substance registered dossier
Diethyl ether--boron trifluoride
203-689-8 109-63-7 Active Full Joint ≥ 100 to < 1 000 tonnes 14-07-2020 View substance registered dossier
Diethyl ether
200-467-2 60-29-7 Active Full Joint ≥ 1 000 to < 10 000 tonnes 28-09-2021 View substance registered dossier
Diethyl disulphide
203-805-7 110-81-6 Active Intermediate Joint Intermediate use only 26-07-2017 View substance registered dossier
Diethyl dipropylmalonate
227-998-2 6065-63-0 Active Intermediate Individual Intermediate use only 27-09-2011 View substance registered dossier
Diethyl diethylmalonate
201-016-2 77-25-8 Active Intermediate Joint Intermediate use only 03-02-2017 View substance registered dossier
Diethyl diallylmalonate
221-696-4 3195-24-2 Active Intermediate Individual Intermediate use only 13-09-2011 View substance registered dossier
Diethyl cyclopropane-1,1-dicarboxylate
216-321-6 1559-02-0 Active Intermediate Individual Intermediate use only 31-08-2016 View substance registered dossier
Diethyl chloromalonate
237-913-0 14064-10-9 Active Intermediate Joint Intermediate use only 21-02-2013 View substance registered dossier
Diethyl carbonate
203-311-1 105-58-8 Active Full Joint ≥ 1 000 to < 10 000 tonnes 14-09-2021 View substance registered dossier
Diethyl carbonate
203-311-1 105-58-8 No longer Valid Full Individual No longer valid 28-05-2013 View substance registered dossier
Diethyl butylmalonate
205-089-1 133-08-4 Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate
220-482-8 2781-11-5 Active Full Joint ≥ 100 to < 1 000 tonnes 13-11-2018 View substance registered dossier
Diethyl benzylmalonate
210-142-7 607-81-8 Active Intermediate Joint Intermediate use only 17-01-2018 View substance registered dossier
Diethyl aminomalonate hydrochloride
236-556-8 13433-00-6 Active Intermediate Joint Intermediate use only 20-12-2017 View substance registered dossier
Diethyl adipate
205-477-0 141-28-6 Active Intermediate Joint Intermediate use only 10-03-2021 View substance registered dossier
Diethyl acetylsuccinate
214-223-8 1115-30-6 Active Intermediate Joint Intermediate use only 23-01-2017 View substance registered dossier
Diethyl acetamidomalonate
213-952-9 1068-90-2 Active Intermediate Joint Intermediate use only 09-07-2020 View substance registered dossier
Diethyl [S-(R*,R*)]-tartrate
237-458-8 13811-71-7 Active Intermediate Joint Intermediate use only 29-04-2019 View substance registered dossier
Diethyl [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]phosphonate
213-551-9 976-56-7 Active Full Joint ≥ 10 to < 100 tonnes 23-07-2019 View substance registered dossier
Diethyl [4-(prop-2-yn-1-yloxy)benzylidene]propanedioate
700-329-6 146763-69-1 Active Intermediate Joint Intermediate use only 29-08-2018 View substance registered dossier
diethyl [2-(2,4-difluorophenyl)prop-2-en-1-yl]malonate
619-693-1 159276-62-7 Active Intermediate Joint Intermediate use only 02-09-2014 View substance registered dossier
Diethyl 4-oxopentane-1,2-dicarboxylate
413-860-0 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
Diethyl 4-oxopentane-1,2-dicarboxylate
413-860-0 - Active Intermediate Individual Intermediate use only 14-12-2012 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active Diethyl ethoxymethylenemalonate 201-725-7 87-13-8 2019 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active Diethyl ethoxymethylenemalonate 201-725-7 87-13-8 2017 View substance registered dossier
DOW AGROSCIENCES B.V. (BE) Rue Montoyer 25, 1000 Brussels Belgium Belgium Active Diethyl ethoxymethylenemalonate 201-725-7 87-13-8 - View substance registered dossier
Corteva Agriscience France S.A.S. Immeuble Equinoxe 2 1bis avenue du 8 Mai 1945 78280 Guyancourt France France Active Diethyl ethoxymethylenemalonate 201-725-7 87-13-8 2015 View substance registered dossier
OQEMA LIMITED (IRELAND) Millienium House Athlone Road N39YW40 Ballymahon, Co Longford Ireland Ireland Active Diethyl ethoxymethylenemalonate 201-725-7 87-13-8 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active Diethyl ether--boron trifluoride 203-689-8 109-63-7 - View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Diethyl ether--boron trifluoride 203-689-8 109-63-7 - View substance registered dossier
REACHLaw Ltd Vänrikinkuja 3 JK 21 FI-02600 ESPOO helsinki Finland Finland Active Diethyl ether--boron trifluoride 203-689-8 109-63-7 2020 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Diethyl ether--boron trifluoride 203-689-8 109-63-7 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Sigma-Aldrich Company Limited The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom United Kingdom No longer Valid Diethyl ether 200-467-2 60-29-7 2021 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Ineos Solvents Germany GmbH Roemerstr. 733 47443 Moers Germany Germany Active Diethyl ether 200-467-2 60-29-7 2010; 2012; 2015; 2018; 2019; 2020; 2021 View substance registered dossier
Honeywell Specialty Chemicals Seelze GmbH Wunstorfer Str. 40 30926 Seelze Deutschland Germany Germany Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
INEOS Chemicals Grangemouth Ltd (Enterprises) DeerLeap Chapel Lane SO43 7FG Lyndhurst Hampshire United Kingdom United Kingdom No longer Valid Diethyl ether 200-467-2 60-29-7 2021 View substance registered dossier
POLYNT S.p.A. via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy Italy Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Mesko S.A Legionow 122 26-111 Skarzysko-Kamienna Poland Poland Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
SIGMA-ALDRICH CHIMIE SARL 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France France Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Nammo Vihtavuori Oy Ruutitehtaantie 80 41330 Vihtavuori Finland Finland Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Scharlab S.L. Gato Pérez, 33 08181 Sentmenat Barcelona Spain Spain Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active Diethyl disulphide 203-805-7 110-81-6 2017 View substance registered dossier
DuPont Nutrition Biosciences ApS Langebrogade 1 DK-1001 Copenhagen Denmark Denmark Active Diethyl dipropylmalonate 227-998-2 6065-63-0 - View substance registered dossier
Chemische Fabrik Berg GmbH Mainthalstrasse 3 06749 Bitterfeld-Wolfen Germany Germany Active Diethyl diethylmalonate 201-016-2 77-25-8 - View substance registered dossier
DuPont Nutrition Biosciences ApS Langebrogade 1 DK-1001 Copenhagen Denmark Denmark Active Diethyl diallylmalonate 221-696-4 3195-24-2 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active Diethyl cyclopropane-1,1-dicarboxylate 216-321-6 1559-02-0 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active Diethyl chloromalonate 237-913-0 14064-10-9 - View substance registered dossier
FRAMOCHEM Szerviz u. 5. H-3700 Kazincbarcika Borsod-Abauj-Zemplen Hungary Hungary Active Diethyl carbonate 203-311-1 105-58-8 2016 View substance registered dossier
Novasol S.A. Mechelsesteenweg 455 1950 Kraainem Belgium Belgium Active Diethyl carbonate 203-311-1 105-58-8 2013; 2016; 2020 View substance registered dossier
Chemical Inspection & Regulation Service Limited (SHINGHWA CHEMICAL CORPORATION) Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland Ireland Active Diethyl carbonate 203-311-1 105-58-8 2019; 2020 View substance registered dossier
TSE, OR for NPU Amstelplein 1 1096 HA Amsterdam Netherlands Netherlands Active Diethyl carbonate 203-311-1 105-58-8 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture Diethyl carbonate 203-311-1 105-58-8 2019 View substance registered dossier
Red Orchid Consulting Oy Ltd (DONGYING HI-TECH SPRING CHEMICAL INDUSTRY CO., LTD) Viherkallionkuja 3 I 59 02710 Espoo Finland Finland Active Diethyl carbonate 203-311-1 105-58-8 - View substance registered dossier
knoell Germany – OR – A1 Konrad-Zuse-Ring 25 68163 Mannheim Germany Germany Active Diethyl carbonate 203-311-1 105-58-8 - View substance registered dossier
BASF Schwarzheide GmbH Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany Germany Cease Manufacture Diethyl carbonate 203-311-1 105-58-8 2014 View substance registered dossier
UBE Europe GmbH (UBE-G) Immermannstrasse 65b 40210 Duesseldorf Germany Germany Active Diethyl carbonate 203-311-1 105-58-8 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Diethyl carbonate 203-311-1 105-58-8 - View substance registered dossier
Jobachem GmbH Am Burgberg 13 37586 Dassel Lower Saxony Germany Germany No longer Valid Diethyl carbonate 203-311-1 105-58-8 2017 View substance registered dossier
KHBoddin GmbH Hartzloh 25 22307 Hamburg Hamburg Germany Germany Active Diethyl butylmalonate 205-089-1 133-08-4 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Diethyl butylmalonate 205-089-1 133-08-4 - View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Active Diethyl butylmalonate 205-089-1 133-08-4 - View substance registered dossier
Metadynea Austria GmbH Hafenstrasse 77 A-3500 Krems Austria Austria Active Diethyl bis(2-hydroxyethyl)aminomethylphosphonate 220-482-8 2781-11-5 - View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Active Diethyl bis(2-hydroxyethyl)aminomethylphosphonate 220-482-8 2781-11-5 2018 View substance registered dossier
ICL-IP Bitterfeld GmbH Rudolph-Glauber-Strasse 7 06749 Bitterfeld Germany Germany Active Diethyl bis(2-hydroxyethyl)aminomethylphosphonate 220-482-8 2781-11-5 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Diethyl benzylmalonate 210-142-7 607-81-8 2018 View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active Diethyl benzylmalonate 210-142-7 607-81-8 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active Diethyl aminomalonate hydrochloride 236-556-8 13433-00-6 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active Diethyl aminomalonate hydrochloride 236-556-8 13433-00-6 2017 View substance registered dossier
Miltitz Aromatics GmbH Chemiepark Bitterfeld-Wolfen Riechstoffstrasse 1 06803 Bitterfeld-Wolfen Germany Germany Active Diethyl adipate 205-477-0 141-28-6 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active Diethyl adipate 205-477-0 141-28-6 - View substance registered dossier
NOVAPEX OR 21 chemin de la Sauvegarde « 21 Ecully Parc » CS 33167 69134 Ecully France France Active Diethyl adipate 205-477-0 141-28-6 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active Diethyl acetylsuccinate 214-223-8 1115-30-6 - View substance registered dossier
IM Chemicals GmbH St.-Peter-Straße 25 4020 Linz Austria Austria Active Diethyl acetylsuccinate 214-223-8 1115-30-6 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active Diethyl acetamidomalonate 213-952-9 1068-90-2 2020 View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active Diethyl acetamidomalonate 213-952-9 1068-90-2 - View substance registered dossier
Central Glass Germany GmbH Kantstrasse 2 33790 Halle/Westf. Nordrhein Westfalen Germany Germany Active Diethyl acetamidomalonate 213-952-9 1068-90-2 - View substance registered dossier
ASTRAZENECA DUNKERQUE PRODUCTION 224, avenue de la Dordogne 59640 DUNKERQUE France France Active Diethyl [S-(R*,R*)]-tartrate 237-458-8 13811-71-7 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active Diethyl [S-(R*,R*)]-tartrate 237-458-8 13811-71-7 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active Diethyl [S-(R*,R*)]-tartrate 237-458-8 13811-71-7 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Diethyl [S-(R*,R*)]-tartrate 237-458-8 13811-71-7 - View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active Diethyl [S-(R*,R*)]-tartrate 237-458-8 13811-71-7 2016 View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active Diethyl [S-(R*,R*)]-tartrate 237-458-8 13811-71-7 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture Diethyl [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]phosphonate 213-551-9 976-56-7 2019 View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Active Diethyl [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]phosphonate 213-551-9 976-56-7 2019 View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active Diethyl [4-(prop-2-yn-1-yloxy)benzylidene]propanedioate 700-329-6 146763-69-1 - View substance registered dossier
Only representative (No publishable name) - - Active Diethyl [4-(prop-2-yn-1-yloxy)benzylidene]propanedioate 700-329-6 146763-69-1 2018 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active diethyl [2-(2,4-difluorophenyl)prop-2-en-1-yl]malonate 619-693-1 159276-62-7 2014 View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active diethyl [2-(2,4-difluorophenyl)prop-2-en-1-yl]malonate 619-693-1 159276-62-7 - View substance registered dossier
ESIM Chemicals GmbH St.-Peter-Strasse 25 4020 Linz Austria Austria Active Diethyl 4-oxopentane-1,2-dicarboxylate 413-860-0 - - View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid Diethyl 4-oxopentane-1,2-dicarboxylate 413-860-0 - 2021 View substance registered dossier
POLYNT S.p.A. via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy Italy Active Diethyl 4-oxopentane-1,2-dicarboxylate 413-860-0 - 2012 View substance registered dossier

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