Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
4-Butoxy-2,3-difluor-4'-methyl-1,1'-biphenyl
938-422-0 - Active Full Joint ≥ 0 to < 10 tonnes 13-05-2019 View substance registered dossier
4-Butoxy-4'-ethoxy-2',3,3'-trifluoro-[1,1'-biphenyl]-2-ol
- - Active Intermediate Joint Intermediate use only 21-06-2022 View substance registered dossier
4-Butyl-4''-ethyl-2',3'-difluor-1,1':4',1''-terphenyl
610-428-5 486406-09-1 Active Full Joint ≥ 1 to < 10 tonnes 19-09-2017 View substance registered dossier
4-Butyl-4''-ethyl-2'-fluor-1,1':4',1''-terphenyl
617-357-9 825633-75-8 Active Full Joint ≥ 1 to < 10 tonnes 15-11-2017 View substance registered dossier
4-chlormethyl-4''-methyl-2'-fluor-[1,1':4',1''-terphenyl]
813-181-3 1115233-02-7 Active Intermediate Joint Intermediate use only 29-07-2021 View substance registered dossier
4-chloro-1'-(4-methoxyphenyl)benzohydrazide
240-441-8 16390-07-1 Active Intermediate Joint Intermediate use only 30-10-2017 View substance registered dossier
4-Chloro-1-(2-mehtylpropyl-1H-imidazo[4,5-c]quinoline
619-386-2 99010-64-7 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
4-chloro-1-(dichloromethyl)benzene
237-721-7 13940-94-8 Active Intermediate Joint Intermediate use only 04-08-2017 View substance registered dossier
4-chloro-1-methylpiperidinium chloride
226-375-2 5382-23-0 Active Full Joint ≥ 1 to < 10 tonnes 05-04-2018 View substance registered dossier
4-chloro-2,5-dimethoxyaniline
228-782-0 6358-64-1 Active Intermediate Joint Intermediate use only 23-09-2021 View substance registered dossier
4-chloro-2,6-diaminopyrimidine
205-863-9 156-83-2 Active Intermediate Joint Intermediate use only 02-03-2020 View substance registered dossier
4-chloro-2-nitroaniline 201-925-4 89-63-4 Active Intermediate Joint Intermediate use only 07-12-2017 View substance registered dossier
4-chloro-2-nitrobenzoic acid
228-483-5 6280-88-2 Active Intermediate Joint Intermediate use only 04-08-2017 View substance registered dossier
4-chloro-2-nitrophenol
201-927-5 89-64-5 Active Intermediate Joint Intermediate use only 31-07-2017 View substance registered dossier
4-chloro-3',4'-dimethoxybenzophenone
CDMBP; CDMP
404-610-1 116412-83-0 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-chloro-3,5-xylenol
201-793-8 88-04-0 Active Full Joint ≥ 1 to < 10 tonnes 05-07-2018 View substance registered dossier
4-chloro-3-methylbenzene-1,2-diaminehydrochloride (1:1)
814-904-5 1087743-89-2 Active Intermediate Joint Intermediate use only 18-07-2018 View substance registered dossier
4-chloro-3-nitro-5-sulphamoylbenzoic acid
245-310-9 22892-96-2 Active Intermediate Joint Intermediate use only 05-11-2020 View substance registered dossier
4-chloro-3-nitrobenzenesulphonamide
202-559-8 97-09-6 Active Intermediate Joint Intermediate use only 22-03-2021 View substance registered dossier
4-chloro-3-nitrobenzenesulphonyl chloride
202-558-2 97-08-5 Active Intermediate Joint Intermediate use only 22-03-2021 View substance registered dossier
4-chloro-3-nitrobenzoic acid
202-550-9 96-99-1 Active Intermediate Joint Intermediate use only 20-04-2017 View substance registered dossier
4-chloro-3-pyridinesulphonamide
251-434-4 33263-43-3 Active Intermediate Joint Intermediate use only 06-06-2018 View substance registered dossier
4-chloro-4'-fluorobutyrophenone
223-395-3 3874-54-2 Active Full Joint ≥ 1 to < 10 tonnes 27-06-2022 View substance registered dossier
4-chloro-4'-hydroxybenzophenone
255-627-4 42019-78-3 Active Intermediate Joint Intermediate use only 23-02-2018 View substance registered dossier
4-chloro-4'-hydroxybenzophenone
255-627-4 42019-78-3 Active Intermediate Joint Intermediate use only 06-06-2013 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-Butoxy-2,3-difluor-4'-methyl-1,1'-biphenyl 938-422-0 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-Butoxy-4'-ethoxy-2',3,3'-trifluoro-[1,1'-biphenyl]-2-ol - - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-Butyl-4''-ethyl-2',3'-difluor-1,1':4',1''-terphenyl 610-428-5 486406-09-1 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-Butyl-4''-ethyl-2'-fluor-1,1':4',1''-terphenyl 617-357-9 825633-75-8 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-chlormethyl-4''-methyl-2'-fluor-[1,1':4',1''-terphenyl] 813-181-3 1115233-02-7 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active 4-chloro-1'-(4-methoxyphenyl)benzohydrazide 240-441-8 16390-07-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 4-chloro-1'-(4-methoxyphenyl)benzohydrazide 240-441-8 16390-07-1 - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-Chloro-1-(2-mehtylpropyl-1H-imidazo[4,5-c]quinoline 619-386-2 99010-64-7 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-chloro-1-(dichloromethyl)benzene 237-721-7 13940-94-8 - View substance registered dossier
WeylChem Höchst GmbH Brüningstr. 50 D-65929 Frankfurt am Main Germany Germany Active 4-chloro-1-(dichloromethyl)benzene 237-721-7 13940-94-8 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active 4-chloro-1-methylpiperidinium chloride 226-375-2 5382-23-0 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 4-chloro-1-methylpiperidinium chloride 226-375-2 5382-23-0 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 4-chloro-2,5-dimethoxyaniline 228-782-0 6358-64-1 2021 View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Cease Manufacture 4-chloro-2,5-dimethoxyaniline 228-782-0 6358-64-1 2019 View substance registered dossier
ICROM S.r.l Via delle arti, 33 20863 Concorezzo Italy Italy Active 4-chloro-2,6-diaminopyrimidine 205-863-9 156-83-2 - View substance registered dossier
Trifarma S.p.A. Via G. Guarini Matteucci 1 20162 Milan (MI) Italy Italy Active 4-chloro-2,6-diaminopyrimidine 205-863-9 156-83-2 - View substance registered dossier
NOVEAL 16 rue Maurice Berteaux 95500 LE THILLAY France France Cease Manufacture 4-chloro-2,6-diaminopyrimidine 205-863-9 156-83-2 2022 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-chloro-2,6-diaminopyrimidine 205-863-9 156-83-2 - View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active 4-chloro-2,6-diaminopyrimidine 205-863-9 156-83-2 - View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 69451 Lyon Cedex 06 France France Active 4-chloro-2,6-diaminopyrimidine 205-863-9 156-83-2 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 4-chloro-2,6-diaminopyrimidine 205-863-9 156-83-2 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 4-chloro-2,6-diaminopyrimidine 205-863-9 156-83-2 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-chloro-2-nitroaniline 201-925-4 89-63-4 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 4-chloro-2-nitroaniline 201-925-4 89-63-4 - View substance registered dossier
Ferro Performance Pigments Belgium N.V. Kortrijkstraat 153 8930 Menen Belgium Belgium Active 4-chloro-2-nitroaniline 201-925-4 89-63-4 - View substance registered dossier
Univar Solutions GmbH Hinsbecker Löh 10c 45257 Essen Germany Germany Active 4-chloro-2-nitroaniline 201-925-4 89-63-4 - View substance registered dossier
Sun Chemical Colors & Effects GmbH An der Rheinschanze 1 67059 Ludwigshafen Germany Germany Active 4-chloro-2-nitroaniline 201-925-4 89-63-4 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-chloro-2-nitrobenzoic acid 228-483-5 6280-88-2 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active 4-chloro-2-nitrophenol 201-927-5 89-64-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-chloro-3',4'-dimethoxybenzophenone 404-610-1 116412-83-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 4-chloro-3',4'-dimethoxybenzophenone 404-610-1 116412-83-0 - View substance registered dossier
UMCO GmbH Georg-Wilhelm-Straße 187 21107 Hamburg Germany Germany Active 4-chloro-3,5-xylenol 201-793-8 88-04-0 2018 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active 4-chloro-3-methylbenzene-1,2-diaminehydrochloride (1:1) 814-904-5 1087743-89-2 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-chloro-3-nitro-5-sulphamoylbenzoic acid 245-310-9 22892-96-2 - View substance registered dossier
Kemikos s.r.l. Via Carolina Romani, 2/A 20091 Bresso (MI) Italy Italy Active 4-chloro-3-nitro-5-sulphamoylbenzoic acid 245-310-9 22892-96-2 2020 View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active 4-chloro-3-nitrobenzenesulphonamide 202-559-8 97-09-6 - View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active 4-chloro-3-nitrobenzenesulphonyl chloride 202-558-2 97-08-5 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Cease Manufacture 4-chloro-3-nitrobenzoic acid 202-550-9 96-99-1 2017 View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 4-chloro-3-nitrobenzoic acid 202-550-9 96-99-1 2017 View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 4-chloro-3-pyridinesulphonamide 251-434-4 33263-43-3 - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active 4-chloro-3-pyridinesulphonamide 251-434-4 33263-43-3 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active 4-chloro-4'-fluorobutyrophenone 223-395-3 3874-54-2 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-chloro-4'-fluorobutyrophenone 223-395-3 3874-54-2 2022 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 4-chloro-4'-fluorobutyrophenone 223-395-3 3874-54-2 - View substance registered dossier
Aceto France S.A.S 3 Rue de Genève 69451 Lyon Cedex 06 France France Active 4-chloro-4'-fluorobutyrophenone 223-395-3 3874-54-2 2019 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active 4-chloro-4'-fluorobutyrophenone 223-395-3 3874-54-2 2017 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-chloro-4'-hydroxybenzophenone 255-627-4 42019-78-3 2017 View substance registered dossier
Comercio de Primeras Materias, S.L. Pablo Picaso, 15 08213 Polinya Barcelona Spain Spain Active 4-chloro-4'-hydroxybenzophenone 255-627-4 42019-78-3 - View substance registered dossier
REACh ChemConsult GmbH Strehlener Str. 14 01069 Dresden Germany Germany Active 4-chloro-4'-hydroxybenzophenone 255-627-4 42019-78-3 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 4-chloro-4'-hydroxybenzophenone 255-627-4 42019-78-3 - View substance registered dossier
Globalquimia, S.L.U. Avenida Diagonal, 519, 1º 1ª 08029 Barcelona Spain Spain Spain Active 4-chloro-4'-hydroxybenzophenone 255-627-4 42019-78-3 2014; 2017 View substance registered dossier
Prosyntis S.A.S. 10 Allée des Champs-Elysées 91042 Evry cedex France France Active 4-chloro-4'-hydroxybenzophenone 255-627-4 42019-78-3 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 4-chloro-4'-hydroxybenzophenone 255-627-4 42019-78-3 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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