Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
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Category:
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Details
4-fluorobenzylamine
205-430-4 140-75-0 Active Intermediate Joint Intermediate use only 15-02-2018 View substance registered dossier
4-fluorophenol
206-736-0 371-41-5 Active Full Joint ≥ 0 to < 10 tonnes 23-09-2016 View substance registered dossier
4-fluorophenol
206-736-0 371-41-5 No longer Valid Intermediate Joint No longer valid 03-10-2019 View substance registered dossier
4-formyl-2-methoxyphenyl isobutyrate
243-956-6 20665-85-4 Active Full Joint ≥ 10 to < 100 tonnes 01-11-2018 View substance registered dossier
4-formyl-3-methoxybenzonitrile
804-777-4 21962-45-8 Active Intermediate Joint Intermediate use only 14-09-2020 View substance registered dossier
4-formyl-N-isopropylbenzamide
236-247-8 13255-50-0 Active Intermediate Joint Intermediate use only 17-03-2018 View substance registered dossier
4-formylbenzoic acid
210-607-4 619-66-9 Active Intermediate Joint Intermediate use only 20-01-2017 View substance registered dossier
4-formylphenylboronic acid
438-670-5 87199-17-5 Active Full Joint ≥ 10 tonnes 09-01-2020 View substance registered dossier
4-guanidinobenzoic acid hydrochloride
255-956-3 42823-46-1 Active Intermediate Joint Intermediate use only 29-05-2017 View substance registered dossier
4-hexadecyl-1-phenylpyrazolidin-3-one
430-840-7 - Active NONS Joint Tonnage data confidential 10-03-2011 View substance registered dossier
4-hydrazinobenzoic acid
210-609-5 619-67-0 Active Intermediate Joint Intermediate use only 22-01-2016 View substance registered dossier
4-hydroxy-1-methyl-3-[(4-nitrophenyl)azo]-2-quinolone
233-310-1 10114-46-2 Active Full Joint ≥ 1 to < 10 tonnes 16-05-2018 View substance registered dossier
4-hydroxy-2,2,6,6-tetramethylpiperidine-1-ethanol
258-132-1 52722-86-8 Active Full Joint ≥ 1 000 to < 10 000 tonnes 06-06-2019 View substance registered dossier
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl
218-760-9 2226-96-2 Active Full Joint ≥ 1 000 to < 10 000 tonnes 24-03-2021 View substance registered dossier
4-hydroxy-2,5-dimethylfuran-2(3H)-one
222-908-8 3658-77-3 Active Full Joint ≥ 10 to < 100 tonnes 20-12-2019 View substance registered dossier
4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylicacidisopropylester-1,1-dioxide
641-726-3 118854-48-1 Active Intermediate Joint Intermediate use only 19-06-2020 View substance registered dossier
4-hydroxy-2-methylnaphthyl benzoate
218-647-4 2211-28-1 Active Intermediate Joint Intermediate use only 05-03-2020 View substance registered dossier
4-hydroxy-3,5-dimethoxybenzaldehyde
205-167-5 134-96-3 Active Intermediate Joint Intermediate use only 22-01-2019 View substance registered dossier
4-hydroxy-3,5-dimethoxybenzonitrile
700-251-2 72684-95-8 Active Full Joint ≥ 1 to < 10 tonnes 28-03-2019 View substance registered dossier
4-hydroxy-3,5-dimethylbenzaldehyde
218-774-5 2233-18-3 Active Intermediate Joint Intermediate use only 11-09-2020 View substance registered dossier
4-Hydroxy-3,5-dimethylbenzonitrile
452-810-2 - Active Full Joint ≥ 1 to < 10 tonnes 23-05-2018 View substance registered dossier
4-hydroxy-3-[(2-hydroxy-4-nitrophenyl)azo]naphthalenesulphonic acid
227-654-1 5924-52-7 Active Intermediate Joint Intermediate use only 15-03-2018 View substance registered dossier
4-hydroxy-3-methoxy-5-nitrobenzoic acid
819-935-8 15785-54-3 Active Intermediate Joint Intermediate use only 08-01-2019 View substance registered dossier
4-hydroxy-3-methoxycinnamic acid
214-490-0 1135-24-6 Active Intermediate Joint Intermediate use only 05-10-2020 View substance registered dossier
4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one
949-712-1 - Active Intermediate Joint Intermediate use only 11-02-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active 4-fluorobenzylamine 205-430-4 140-75-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 4-fluorobenzylamine 205-430-4 140-75-0 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 4-fluorobenzylamine 205-430-4 140-75-0 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 4-fluorophenol 206-736-0 371-41-5 - View substance registered dossier
Corteva Agriscience France S.A.S. Immeuble Equinoxe 2 1bis avenue du 8 Mai 1945 78280 Guyancourt France France Active 4-fluorophenol 206-736-0 371-41-5 - View substance registered dossier
Wychem Limited Bury Road CB8 8YN Stradishall Suffolk United Kingdom United Kingdom No longer Valid 4-fluorophenol 206-736-0 371-41-5 2021 View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active 4-formyl-2-methoxyphenyl isobutyrate 243-956-6 20665-85-4 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active 4-formyl-2-methoxyphenyl isobutyrate 243-956-6 20665-85-4 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 4-formyl-3-methoxybenzonitrile 804-777-4 21962-45-8 2019; 2020 View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active 4-formyl-3-methoxybenzonitrile 804-777-4 21962-45-8 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 4-formyl-N-isopropylbenzamide 236-247-8 13255-50-0 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active 4-formylbenzoic acid 210-607-4 619-66-9 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 4-formylphenylboronic acid 438-670-5 87199-17-5 2012; 2017; 2018; 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-formylphenylboronic acid 438-670-5 87199-17-5 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active 4-guanidinobenzoic acid hydrochloride 255-956-3 42823-46-1 - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Active 4-hexadecyl-1-phenylpyrazolidin-3-one 430-840-7 - 2011 View substance registered dossier
Honeywell Specialty Chemicals Seelze GmbH Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany Germany Cease Manufacture 4-hexadecyl-1-phenylpyrazolidin-3-one 430-840-7 - 2020 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-hydrazinobenzoic acid 210-609-5 619-67-0 - View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Active 4-hydroxy-1-methyl-3-[(4-nitrophenyl)azo]-2-quinolone 233-310-1 10114-46-2 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-ethanol 258-132-1 52722-86-8 2019 View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Active 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-ethanol 258-132-1 52722-86-8 2016 View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-ethanol 258-132-1 52722-86-8 2016 View substance registered dossier
SABO SPA Via Caravaggi 24040 Levate Bergamo Italy Italy Active 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-ethanol 258-132-1 52722-86-8 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-ethanol 258-132-1 52722-86-8 - View substance registered dossier
SI Group Germany (DEAB) GmbH Teplitzer Strasse 14-16 84478 Waldkraiburg Germany Germany Active 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-ethanol 258-132-1 52722-86-8 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-ethanol 258-132-1 52722-86-8 - View substance registered dossier
Rianlon GmbH Charlottenstr. 75 40210 Duesseldorf Germany Germany Active 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-ethanol 258-132-1 52722-86-8 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-ethanol 258-132-1 52722-86-8 2016 View substance registered dossier
3V Sigma S.p.A Torquato Tasso 58 24121 Bergamo Italy Italy Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland Ireland Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 2019 View substance registered dossier
VUP a.s. Nabrezna 4 97104 Prievidza Slovakia Slovakia Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 - View substance registered dossier
SUEZ Water Technologies & Solutions Belgium BVBA Toekomstlaan 54 2200 Herentals Belgium Belgium Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 2018 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 2014; 2019 View substance registered dossier
Reach & Colours Trade Kft Levente u. 14/a 2161 Csomád Hungary Hungary Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 - View substance registered dossier
Nufarm GmbH & Co.KG OR St.-Peter-Str.25 4021 Linz Austria Austria Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 2014; 2015; 2017; 2019; 2021 View substance registered dossier
Reach & Colours s.r.o Thunovská 196/19 Malá Strana 118 00 Prague Czech Republic Czech Republic Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 - View substance registered dossier
SUEZ WTS France Tour CB21 16 Place de l’Iris 92040 Paris La Défense France France Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 - View substance registered dossier
REACH24H CONSULTING GROUP (acts as the OR for SUQIAN UNITECH CORP., LTD) Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 2018; 2019; 2020 View substance registered dossier
CHIMEC S.p.A. Via delle Ande 19 00144 Roma Italy Italy Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 - View substance registered dossier
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 2020 View substance registered dossier
Nalco Europe B.V. Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands Netherlands Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 2016 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany No longer Valid 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 2015; 2019 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2 2020 View substance registered dossier
FIRMENICH PRODUCTION S.A.S. BP 23 766, route Roger Firmenich 40260 Castets France France Active 4-hydroxy-2,5-dimethylfuran-2(3H)-one 222-908-8 3658-77-3 2018 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 4-hydroxy-2,5-dimethylfuran-2(3H)-one 222-908-8 3658-77-3 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 4-hydroxy-2,5-dimethylfuran-2(3H)-one 222-908-8 3658-77-3 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylicacidisopropylester-1,1-dioxide 641-726-3 118854-48-1 - View substance registered dossier
DSM Nutritional Products France SAS 1 boulevard d'Alsace F-68128 Village-Neuf France France Active 4-hydroxy-2-methylnaphthyl benzoate 218-647-4 2211-28-1 2020 View substance registered dossier
Agfa-Gevaert N.V. Septestraat 27 2640 Mortsel Belgium Belgium Active 4-hydroxy-3,5-dimethoxybenzaldehyde 205-167-5 134-96-3 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 4-hydroxy-3,5-dimethoxybenzaldehyde 205-167-5 134-96-3 - View substance registered dossier
Genencor International B.V. - OR-US Willem Einthovenstraat 4 2342 BH Oegstgeest Netherlands Netherlands Active 4-hydroxy-3,5-dimethoxybenzonitrile 700-251-2 72684-95-8 - View substance registered dossier
Genencor International Oy Tiilikantie 15 FI-42300 Jämsänkoski Finland Finland Active 4-hydroxy-3,5-dimethoxybenzonitrile 700-251-2 72684-95-8 2012; 2019 View substance registered dossier
Výzkumný ústav organických syntéz a.s. č.p. 296 533 54 Rybitví Czech Republic Czech Republic Active 4-hydroxy-3,5-dimethylbenzaldehyde 218-774-5 2233-18-3 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active 4-hydroxy-3,5-dimethylbenzaldehyde 218-774-5 2233-18-3 - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-Hydroxy-3,5-dimethylbenzonitrile 452-810-2 - 2018 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-hydroxy-3-[(2-hydroxy-4-nitrophenyl)azo]naphthalenesulphonic acid 227-654-1 5924-52-7 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 4-hydroxy-3-methoxy-5-nitrobenzoic acid 819-935-8 15785-54-3 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active 4-hydroxy-3-methoxy-5-nitrobenzoic acid 819-935-8 15785-54-3 - View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active 4-hydroxy-3-methoxycinnamic acid 214-490-0 1135-24-6 2020 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active 4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one 949-712-1 - - View substance registered dossier

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