Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid
691-120-8 486460-00-8 Active Intermediate Joint Intermediate use only 31-05-2022 View substance registered dossier
(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1-one hydrochloride
813-550-9 486459-71-6 Active Intermediate Joint Intermediate use only 28-02-2022 View substance registered dossier
(R)-3-chloropropane-1,2-diol
435-560-9 57090-45-6 Active Intermediate Joint Intermediate use only 25-04-2018 View substance registered dossier
(R)-3-chloropropane-1,2-diol
435-560-9 57090-45-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(R)-3-cyclohexyl-2-hydroxypropionic acid
812-501-9 156469-00-0 Active Intermediate Joint Intermediate use only 01-06-2018 View substance registered dossier
(R)-3-Methylhexanoic acid
471-550-0 22328-90-1 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-3-phenyllactic acid
230-803-3 7326-19-4 Active Intermediate Joint Intermediate use only 17-05-2018 View substance registered dossier
(R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile
430-760-2 219861-18-4 Active Intermediate Joint Intermediate use only 26-03-2019 View substance registered dossier
(R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile
430-760-2 219861-18-4 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate
949-784-4 - Active Intermediate Individual Intermediate use only 25-03-2019 View substance registered dossier
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide (7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate
920-209-9 - Active Intermediate Joint Intermediate use only 30-05-2018 View substance registered dossier
(R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide
419-800-1 - Active Full Joint ≥ 0 to < 10 tonnes 05-12-2019 View substance registered dossier
(R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide
419-800-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-5-(2-Phenylsulphonylethenyl)-3(N-Methylpyrrolidine-2-ylmethyl)-1-H-indole methane sulphonic acid)
880-102-7 1196663-24-7 Active Intermediate Joint Intermediate use only 22-02-2022 View substance registered dossier
(R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone
801-918-1 168828-84-0 Active Intermediate Individual Intermediate use only 18-01-2016 View substance registered dossier
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
700-798-7 877399-00-3 Active Intermediate Joint Intermediate use only 11-03-2020 View substance registered dossier
(R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole
UK-111,975
422-390-5 143322-57-0 Active NONS Joint Tonnage data confidential 10-04-2020 View substance registered dossier
(R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole
UK-111,975
422-390-5 143322-57-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-5-Bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indol oxalate
846-313-3 1196663-29-2 Active Intermediate Joint Intermediate use only 02-12-2019 View substance registered dossier
(R)-5-isopropyl-2-methylcyclohexa-1,3-diene
224-167-6 4221-98-1 Active Full Joint ≥ 10 to < 100 tonnes 30-05-2018 View substance registered dossier
(R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one
224-957-0 4573-50-6 Active Full Joint ≥ 1 to < 10 tonnes 24-08-2018 View substance registered dossier
(R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one
224-957-0 4573-50-6 Active Intermediate Individual Intermediate use only 11-06-2019 View substance registered dossier
(R)-7-(But-2-yn-1-yl)-8-[3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl]-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione
937-756-4 886588-63-2 Active Intermediate Joint Intermediate use only 28-04-2017 View substance registered dossier
(R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid
264-133-8 63422-71-9 Active Intermediate Joint Intermediate use only 10-10-2022 View substance registered dossier
(R)-cyclohex-3-enecarboxylic acid
634-674-8 5709-98-8 Active Intermediate Joint Intermediate use only 11-09-2017 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1-one hydrochloride 813-550-9 486459-71-6 2022 View substance registered dossier
Labcorp Development SA 169 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 2018 View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 - View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 171 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Cease Manufacture (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 2012 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (R)-3-cyclohexyl-2-hydroxypropionic acid 812-501-9 156469-00-0 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (R)-3-Methylhexanoic acid 471-550-0 22328-90-1 - View substance registered dossier
- - - - (R)-3-Methylhexanoic acid 471-550-0 22328-90-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (R)-3-Methylhexanoic acid 471-550-0 22328-90-1 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (R)-3-phenyllactic acid 230-803-3 7326-19-4 - View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 2019 View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate 949-784-4 - - View substance registered dossier
Synthon, s.r.o. Brněnská 32 678 01 Blansko Czech Republic Czech Republic Active (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide (7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate 920-209-9 - - View substance registered dossier
Astellas Ireland Co.Ltd Damastown Road Damastown Industrial Park NA Mulhuddart Dublin 15 Ireland Ireland Active (R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide 419-800-1 - 2019 View substance registered dossier
- - - - (R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide 419-800-1 - - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active (R)-5-(2-Phenylsulphonylethenyl)-3(N-Methylpyrrolidine-2-ylmethyl)-1-H-indole methane sulphonic acid) 880-102-7 1196663-24-7 - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone 801-918-1 168828-84-0 - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 700-798-7 877399-00-3 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 700-798-7 877399-00-3 2013 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole 422-390-5 143322-57-0 2020 View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole 422-390-5 143322-57-0 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland No longer Valid (R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole 422-390-5 143322-57-0 2013 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (R)-5-Bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indol oxalate 846-313-3 1196663-29-2 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (R)-5-isopropyl-2-methylcyclohexa-1,3-diene 224-167-6 4221-98-1 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (R)-5-isopropyl-2-methylcyclohexa-1,3-diene 224-167-6 4221-98-1 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one 224-957-0 4573-50-6 2018 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one 224-957-0 4573-50-6 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (R)-7-(But-2-yn-1-yl)-8-[3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl]-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione 937-756-4 886588-63-2 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (R)-7-(But-2-yn-1-yl)-8-[3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl]-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione 937-756-4 886588-63-2 2017 View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active (R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid 264-133-8 63422-71-9 2021 View substance registered dossier
REACHLaw Ltd Vänrikinkuja 3 JK 21 02600 Espoo Finland Finland Active (R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid 264-133-8 63422-71-9 2022 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-cyclohex-3-enecarboxylic acid 634-674-8 5709-98-8 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.