Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104978 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
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  • Consumer Uses
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Details
5-hydroxyisophthalic acid
210-565-7 618-83-7 Active Full Joint ≥ 0 to < 10 tonnes 30-11-2018 View substance registered dossier
5-hydroxyisophthalic acid
210-565-7 618-83-7 Active Intermediate Joint Intermediate use only 05-04-2019 View substance registered dossier
5-Iodo-2-Methylbenzoic acid
611-200-8 54811-38-0 Active Intermediate Joint Intermediate use only 19-11-2018 View substance registered dossier
5-Isobenzofurancarboxylic acid, 1,3-dihydro-1,3-dioxo-, reaction products with 1-nonanol
941-303-6 1689576-55-3 Active Full Joint ≥ 100 to < 1 000 tonnes 19-04-2021 View substance registered dossier
5-isopropyl-2-methylbicyclo[3.1.0]hex-2-ene
220-686-7 2867-05-2 Active Intermediate Joint Intermediate use only 07-12-2016 View substance registered dossier
5-isopropylimidazolidine-2,4-dione
634-107-4 16935-34-5 Active Intermediate Joint Intermediate use only 17-06-2013 View substance registered dossier
5-mesyl-2-[(2-nitrophenyl)thio]aniline
298-153-3 93778-19-9 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
5-mesyl-6-nitrobenzoxazol-2(3H)-one
250-795-5 31770-95-3 Active Intermediate Joint Intermediate use only 22-01-2016 View substance registered dossier
5-mesylbenzoxazol-2(3H)-one
237-688-9 13920-98-4 Active Intermediate Joint Intermediate use only 22-01-2016 View substance registered dossier
5-methoxy-2-(2H-1,2,3-triazol-2-yl)benzoic acid
826-805-4 1293284-55-5 Active Intermediate Joint Intermediate use only 09-07-2018 View substance registered dossier
5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl) thio]-1H-benzimidazole
615-997-3 73590-85-9 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
5-methoxy-2-methylsulphanilic acid
229-319-5 6471-78-9 Active Intermediate Joint Intermediate use only 07-06-2016 View substance registered dossier
5-methoxy-4'-(trifluoromethyl)valerophenone
VALEROPHENONE
425-000-1 61718-80-7 Active Intermediate Joint Intermediate use only 18-06-2019 View substance registered dossier
5-methoxy-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one
619-590-1 135302-13-5 Active Intermediate Joint Intermediate use only 24-04-2013 View substance registered dossier
5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium chloride
938-419-4 3904-24-3 Cease Manufacture Full Joint Cease manufacture 04-07-2018 View substance registered dossier
5-methyl-1,3,4-thiadiazole-2(3H)-thione
249-667-1 29490-19-5 Active Intermediate Joint Intermediate use only 29-11-2018 View substance registered dossier
5-methyl-1,3-oxazolidin-2-one
810-292-9 1072-70-4 Active Intermediate Joint Intermediate use only 27-06-2017 View substance registered dossier
5-methyl-1H-imidazole-4-methanol
249-740-8 29636-87-1 Active Intermediate Joint Intermediate use only 27-03-2017 View substance registered dossier
5-methyl-2-(1-methylbutyl)-5-propyl-1,3-dioxane
279-482-1 80480-24-6 Active Full Joint ≥ 1 to < 10 tonnes 20-02-2018 View substance registered dossier
5-methyl-2-(1-methylvinyl)cyclohexan-1-ol
232-102-8 7786-67-6 Active Full Joint ≥ 1 to < 10 tonnes 25-08-2015 View substance registered dossier
5-methyl-2-(1-methylvinyl)cyclohexan-1-ol
232-102-8 7786-67-6 Active Intermediate Joint Intermediate use only 11-01-2017 View substance registered dossier
5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid
689-732-5 956317-36-5 Active Full Joint ≥ 1 to < 10 tonnes 20-08-2019 View substance registered dossier
5-methyl-2-(isopropyl)cyclohexyl nicotinate
254-991-1 40594-65-8 Active Full Joint ≥ 1 to < 10 tonnes 04-02-2019 View substance registered dossier
5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile
421-300-1 138564-59-7 Active Intermediate Joint Intermediate use only 02-09-2021 View substance registered dossier
5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile
421-300-1 138564-59-7 Active NONS Joint Tonnage data confidential 29-07-2011 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
BIOKEM Via Cesare Battisti, 12 21100 Varese Italy Italy Active 5-hydroxyisophthalic acid 210-565-7 618-83-7 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 5-hydroxyisophthalic acid 210-565-7 618-83-7 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active 5-hydroxyisophthalic acid 210-565-7 618-83-7 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 5-hydroxyisophthalic acid 210-565-7 618-83-7 2018 View substance registered dossier
bracco SPIN Piazzale F. Marinotti 1 33050 Torviscosa Italy Italy Active 5-hydroxyisophthalic acid 210-565-7 618-83-7 - View substance registered dossier
Innochem NV B. Adriaensenlaan 66 2450 Meerhout Belgium Belgium Active 5-Iodo-2-Methylbenzoic acid 611-200-8 54811-38-0 - View substance registered dossier
POLYNT S.p.A. via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy Italy Cease Manufacture 5-Isobenzofurancarboxylic acid, 1,3-dihydro-1,3-dioxo-, reaction products with 1-nonanol 941-303-6 1689576-55-3 2019 View substance registered dossier
VALTRIS ENTERPRISES FRANCE ZI Baleycourt 55103 VERDUN FRANCE France France Active 5-Isobenzofurancarboxylic acid, 1,3-dihydro-1,3-dioxo-, reaction products with 1-nonanol 941-303-6 1689576-55-3 2019 View substance registered dossier
Covance Clinical Development SA 098 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5-5 Planta 28050 Madrid Spain Spain Cease Manufacture 5-Isobenzofurancarboxylic acid, 1,3-dihydro-1,3-dioxo-, reaction products with 1-nonanol 941-303-6 1689576-55-3 2020 View substance registered dossier
ExxonMobil Petroleum & Chemical BV Polderdijkweg 2030 Antwerpen Belgium Belgium Active 5-Isobenzofurancarboxylic acid, 1,3-dihydro-1,3-dioxo-, reaction products with 1-nonanol 941-303-6 1689576-55-3 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 5-isopropyl-2-methylbicyclo[3.1.0]hex-2-ene 220-686-7 2867-05-2 - View substance registered dossier
Deretil S.A. Villaricos, s/n 04618 Cuevas del Almanzora Almeria Spain Spain Active 5-isopropylimidazolidine-2,4-dione 634-107-4 16935-34-5 - View substance registered dossier
CENTIPHARM Chemin de la Madeleine 06131 GRASSE FRANCE France France Active 5-mesyl-2-[(2-nitrophenyl)thio]aniline 298-153-3 93778-19-9 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 5-mesyl-6-nitrobenzoxazol-2(3H)-one 250-795-5 31770-95-3 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 5-mesylbenzoxazol-2(3H)-one 237-688-9 13920-98-4 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active 5-methoxy-2-(2H-1,2,3-triazol-2-yl)benzoic acid 826-805-4 1293284-55-5 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl) thio]-1H-benzimidazole 615-997-3 73590-85-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl) thio]-1H-benzimidazole 615-997-3 73590-85-9 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl) thio]-1H-benzimidazole 615-997-3 73590-85-9 - View substance registered dossier
AromataGroup Via Carolina Romani n. 35 20091 Bresso (MI) Italy Italy Active 5-methoxy-2-methylsulphanilic acid 229-319-5 6471-78-9 - View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active 5-methoxy-4'-(trifluoromethyl)valerophenone 425-000-1 61718-80-7 - View substance registered dossier
Synthon, s.r.o. Brněnská 32 678 01 Blansko Czech Republic Czech Republic Active 5-methoxy-4'-(trifluoromethyl)valerophenone 425-000-1 61718-80-7 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 5-methoxy-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one 619-590-1 135302-13-5 - View substance registered dossier
Avara Shannon Pharmaceutical Services Limited Shannon Industrial Estate V14 FX09 Shannon Clare Ireland Ireland Cease Manufacture 5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium chloride 938-419-4 3904-24-3 2021 View substance registered dossier
Intertek Italia SpA_ITAzo Via Miglioli 2/A 20063 CERNUSCO SUL NAVIGLIO Milano Italy Italy Active 5-methyl-1,3,4-thiadiazole-2(3H)-thione 249-667-1 29490-19-5 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 5-methyl-1,3,4-thiadiazole-2(3H)-thione 249-667-1 29490-19-5 2017 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 5-methyl-1,3,4-thiadiazole-2(3H)-thione 249-667-1 29490-19-5 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 5-methyl-1,3-oxazolidin-2-one 810-292-9 1072-70-4 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active 5-methyl-1H-imidazole-4-methanol 249-740-8 29636-87-1 2017 View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 5-methyl-1H-imidazole-4-methanol 249-740-8 29636-87-1 - View substance registered dossier
Kao Corporation, S.A. Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active 5-methyl-2-(1-methylbutyl)-5-propyl-1,3-dioxane 279-482-1 80480-24-6 - View substance registered dossier
SYNAROME SA 34 rue Gutenberg 91070 BONDOUFLE France France Active 5-methyl-2-(1-methylvinyl)cyclohexan-1-ol 232-102-8 7786-67-6 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 5-methyl-2-(1-methylvinyl)cyclohexan-1-ol 232-102-8 7786-67-6 2016; 2017 View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid 689-732-5 956317-36-5 2019 View substance registered dossier
Multichem R&D Srl Viale della Libertà 1 27020 Marcignago (PV) Italy Italy Active 5-methyl-2-(isopropyl)cyclohexyl nicotinate 254-991-1 40594-65-8 2018; 2019 View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active 5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile 421-300-1 138564-59-7 2010; 2012; 2017; 2021 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active 5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile 421-300-1 138564-59-7 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile 421-300-1 138564-59-7 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile 421-300-1 138564-59-7 - View substance registered dossier

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