Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
2-[[4[[4,6-bis[[3-(diethylamino)propyl]amino]-1,3,5-triazine-2-yl]amino]phenyl]azo]-N-(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)-3-oxobutanamide
KAYACEL YELLOW CG; NO.466 BZN
407-680-1 98809-11-1 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
685-521-7 98796-53-3 Active Full Joint ≥ 0 to < 10 tonnes 14-10-2020 View substance registered dossier
5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
685-410-3 98796-51-1 Active Full Joint ≥ 0 to < 10 tonnes 14-10-2020 View substance registered dossier
(2S,3S)-3-(2-ethoxyphenoxy)-2-hydroxy-3-phenylpropylammonium methanesulfonate;reaction mass of: (2R,3R)-3-(2-ethoxyphenoxy)-2-hydroxy-3-phenylpropylammonium methanesulfonate
425-530-3 98769-75-6 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
tert-butyl (1S)-N-[1-((2S)-2-oxiranyl)-2-phenylethyl]carbamate
425-420-5 98737-29-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Ethanone, 2,2-dichloro-1-(2,3-dihydro-3-methyl-4H-1,4-benzoxazin-4-yl)-
619-372-6 98730-04-2 Active Full Joint ≥ 10 to < 100 tonnes 20-12-2021 View substance registered dossier
Synthetic resin, a reaction product of 4,4'-bis(N-maleimido)diphenylmethane with 3-aminobenzoic acid hydrazide
619-370-5 98725-11-2 Active Full Joint ≥ 0 to < 10 tonnes 24-05-2018 View substance registered dossier
Adenosine 5'-(tetrahydrogen triphosphate), disodium salt
213-579-1 987-65-5 Active Full Joint ≥ 1 to < 10 tonnes 20-03-2018 View substance registered dossier
Phosphoric acid, butyl ester, branched, compd. with 2-ethyl-N-(2-ethylhexyl)-1-hexanamine
308-859-6 98679-19-7 Active Full Joint ≥ 10 to < 100 tonnes 14-12-2018 View substance registered dossier
(4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide
623-314-5 98674-86-3 Active Intermediate Joint Intermediate use only 26-03-2018 View substance registered dossier
Phosphoric acid, C8-10-alkyl esters
308-806-7 98653-76-0 Active Full Joint ≥ 0 to < 10 tonnes 29-08-2019 View substance registered dossier
N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
691-258-9 98626-61-0 Active Intermediate Individual Intermediate use only 11-10-2017 View substance registered dossier
1H-Pyrrolo[2,3-b]pyridin-5-ol
802-177-7 98549-88-3 Active Intermediate Individual Intermediate use only 15-01-2015 View substance registered dossier
1H-Pyrrolo[2,3-b]pyridin-5-ol
802-177-7 98549-88-3 Active Intermediate Joint Intermediate use only 23-07-2018 View substance registered dossier
(carboxymethyl)dimethyl[3-[(1-oxoundecenyl)amino]propyl]ammonium hydroxide
308-783-3 98510-75-9 Active Full Joint ≥ 10 to < 100 tonnes 10-06-2016 View substance registered dossier
trans-1,4-bis(isocyanatomethyl)cyclohexane
825-609-6 98458-83-4 Active Full Joint ≥ 1 to < 10 tonnes 11-09-2018 View substance registered dossier
Pregna-1,4-diene-3,20-dione, 11.beta.,16.alpha.,17,21-tetrahydroxy-, 16,21-diacetate
619-343-8 98422-55-0 Active Intermediate Individual Intermediate use only 11-12-2015 View substance registered dossier
1-(2-chlorophenyl)-1,2-dihydro-5H-tetrazol-5-one
426-110-2 98377-35-6 Active Intermediate Individual Intermediate use only 15-01-2015 View substance registered dossier
2,3-Epoxypropyl neodecanoate, oligomeric reaction products with toluene-4-sulfonic acid
500-281-4 98362-33-5 Active Full Joint ≥ 100 to < 1 000 tonnes 26-08-2020 View substance registered dossier
Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
PD 149834
422-380-0 98349-25-8 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
PD 149834
422-380-0 98349-25-8 Active Intermediate Joint Intermediate use only 17-11-2014 View substance registered dossier
Chloro-1-ethyl isopropyl carbonate
CARBONATE DE CHLORO-1-ETHYLE ET ISOPROPYLE
424-590-8 98298-66-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Chloro-1-ethyl isopropyl carbonate
CARBONATE DE CHLORO-1-ETHYLE ET ISOPROPYLE
424-590-8 98298-66-9 Active Intermediate Joint Intermediate use only 18-06-2012 View substance registered dossier
Undecyl glucoside
308-766-0 98283-67-1 Active Full Joint ≥ 10 to < 100 tonnes 07-02-2017 View substance registered dossier
(R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(PYRIDIN-3-YL) PROPIONIC ACID
441-200-1 98266-33-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-[[4[[4,6-bis[[3-(diethylamino)propyl]amino]-1,3,5-triazine-2-yl]amino]phenyl]azo]-N-(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)-3-oxobutanamide 407-680-1 98809-11-1 - View substance registered dossier
- - - - 2-[[4[[4,6-bis[[3-(diethylamino)propyl]amino]-1,3,5-triazine-2-yl]amino]phenyl]azo]-N-(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)-3-oxobutanamide 407-680-1 98809-11-1 - View substance registered dossier
Sigma-Aldrich Biochemie GmbH Georg-Heyken-Str. 14 21147 Hamburg Germany Germany Active N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite] 685-521-7 98796-53-3 2019; 2020 View substance registered dossier
Sigma-Aldrich Biochemie GmbH Georg-Heyken-Str. 14 21147 Hamburg Germany Germany Active 5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite] 685-410-3 98796-51-1 2019; 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (2S,3S)-3-(2-ethoxyphenoxy)-2-hydroxy-3-phenylpropylammonium methanesulfonate;reaction mass of: (2R,3R)-3-(2-ethoxyphenoxy)-2-hydroxy-3-phenylpropylammonium methanesulfonate 425-530-3 98769-75-6 - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (2S,3S)-3-(2-ethoxyphenoxy)-2-hydroxy-3-phenylpropylammonium methanesulfonate;reaction mass of: (2R,3R)-3-(2-ethoxyphenoxy)-2-hydroxy-3-phenylpropylammonium methanesulfonate 425-530-3 98769-75-6 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active tert-butyl (1S)-N-[1-((2S)-2-oxiranyl)-2-phenylethyl]carbamate 425-420-5 98737-29-2 - View substance registered dossier
ASCENZA AGRO, S. A. Avenida do Rio Tejo Herdade das Praias 2910-440 Setúbal Portugal Portugal Active Ethanone, 2,2-dichloro-1-(2,3-dihydro-3-methyl-4H-1,4-benzoxazin-4-yl)- 619-372-6 98730-04-2 2021 View substance registered dossier
Only representative (No publishable name) - - Active Ethanone, 2,2-dichloro-1-(2,3-dihydro-3-methyl-4H-1,4-benzoxazin-4-yl)- 619-372-6 98730-04-2 2009; 2011; 2016; 2019; 2021 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active Synthetic resin, a reaction product of 4,4'-bis(N-maleimido)diphenylmethane with 3-aminobenzoic acid hydrazide 619-370-5 98725-11-2 - View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Active Adenosine 5'-(tetrahydrogen triphosphate), disodium salt 213-579-1 987-65-5 - View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Active Phosphoric acid, butyl ester, branched, compd. with 2-ethyl-N-(2-ethylhexyl)-1-hexanamine 308-859-6 98679-19-7 - View substance registered dossier
[Confidential] - - - Phosphoric acid, butyl ester, branched, compd. with 2-ethyl-N-(2-ethylhexyl)-1-hexanamine 308-859-6 98679-19-7 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide 623-314-5 98674-86-3 - View substance registered dossier
Lubrizol France SAS 25 Quai de France 76100 ROUEN France France Active Phosphoric acid, C8-10-alkyl esters 308-806-7 98653-76-0 - View substance registered dossier
Lubrizol Deutschland GmbH Max-Planck-Strasse 6 27721 RITTERHUDE Germany Germany Active Phosphoric acid, C8-10-alkyl esters 308-806-7 98653-76-0 - View substance registered dossier
Lubrizol Europe Coordination Center BVBA 01 Chaussee De Wavre, 1945 1945 Brussels Belgium Belgium Active Phosphoric acid, C8-10-alkyl esters 308-806-7 98653-76-0 2019 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide 691-258-9 98626-61-0 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active 1H-Pyrrolo[2,3-b]pyridin-5-ol 802-177-7 98549-88-3 - View substance registered dossier
[Confidential] - - - 1H-Pyrrolo[2,3-b]pyridin-5-ol 802-177-7 98549-88-3 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (carboxymethyl)dimethyl[3-[(1-oxoundecenyl)amino]propyl]ammonium hydroxide 308-783-3 98510-75-9 - View substance registered dossier
Charles River Laboratories Den Bosch B.V. OR06 Hambakenwetering 7 5231DD 's-Hertogenbosch Netherlands Netherlands Active trans-1,4-bis(isocyanatomethyl)cyclohexane 825-609-6 98458-83-4 2018 View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active Pregna-1,4-diene-3,20-dione, 11.beta.,16.alpha.,17,21-tetrahydroxy-, 16,21-diacetate 619-343-8 98422-55-0 - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active 1-(2-chlorophenyl)-1,2-dihydro-5H-tetrazol-5-one 426-110-2 98377-35-6 2013; 2015 View substance registered dossier
KLK Kolb Specialties B.V. Langestraat 167 7491AE Delden Overijssel Netherlands Netherlands Active 2,3-Epoxypropyl neodecanoate, oligomeric reaction products with toluene-4-sulfonic acid 500-281-4 98362-33-5 2013; 2017; 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 422-380-0 98349-25-8 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active Ethyl 1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 422-380-0 98349-25-8 - View substance registered dossier
- - - - Chloro-1-ethyl isopropyl carbonate 424-590-8 98298-66-9 - View substance registered dossier
ATUL IRELAND LIMITED OR2 Flynn O'driscoll No.1 Grant's Row Lower Mount Street D02HX96 DUBLIN DUBLIN Ireland Ireland Active Chloro-1-ethyl isopropyl carbonate 424-590-8 98298-66-9 - View substance registered dossier
seppic sa 50 boulevard National CS 90020 92257 La Garenne Colombes ile de france France France Active Undecyl glucoside 308-766-0 98283-67-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid 441-200-1 98266-33-2 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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