Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
L-4-hydroxyproline
200-091-9 51-35-4 Active Intermediate Joint Intermediate use only 03-05-2018 View substance registered dossier
3,5-dichlorobenzoic acid
200-092-4 51-36-5 Active Intermediate Joint Intermediate use only 20-09-2019 View substance registered dossier
DL-thyroxin
200-101-1 51-48-9 Active Full Individual ≥ 1 to < 10 tonnes 10-09-2021 View substance registered dossier
Dexamphetamine
200-112-1 51-64-9 Active Intermediate Joint Intermediate use only 23-10-2018 View substance registered dossier
4-(2-aminoethyl)phenol
200-115-8 51-67-2 Active Full Joint ≥ 1 to < 10 tonnes 06-03-2018 View substance registered dossier
4-(2-aminoethyl)phenol
200-115-8 51-67-2 Active Intermediate Joint Intermediate use only 05-01-2016 View substance registered dossier
N,N,N',N'-tetramethylmethylenediamine
200-124-7 51-80-9 Active Intermediate Joint Intermediate use only 29-10-2014 View substance registered dossier
Morphine hydrochloride
200-136-2 52-26-6 Active Intermediate Joint Intermediate use only 16-03-2017 View substance registered dossier
Bronopol
200-143-0 52-51-7 Active Full Joint ≥ 100 to < 1 000 tonnes 12-03-2020 View substance registered dossier
Cysteine hydrochloride
200-157-7 52-89-1 Active Full Joint ≥ 1 000 to < 10 000 tonnes 03-06-2022 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
CHEMSAFE srl on behalf of AZO INTERNATIONAL CHEMICAL ltd Via Ribes, 5 10010 Colleretto Giacosa TO Italy Italy Active L-4-hydroxyproline 200-091-9 51-35-4 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 3,5-dichlorobenzoic acid 200-092-4 51-36-5 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Active DL-thyroxin 200-101-1 51-48-9 2021 View substance registered dossier
SYNTHEXIM 1 Quai d'Amérique 62 100 calais France France Active Dexamphetamine 200-112-1 51-64-9 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 4-(2-aminoethyl)phenol 200-115-8 51-67-2 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-(2-aminoethyl)phenol 200-115-8 51-67-2 - View substance registered dossier
Taminco BV Pantserschipstraat 207 9000 Gent Belgium Belgium Active N,N,N',N'-tetramethylmethylenediamine 200-124-7 51-80-9 - View substance registered dossier
[Confidential] - - - Morphine hydrochloride 200-136-2 52-26-6 - View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Active Bronopol 200-143-0 52-51-7 - View substance registered dossier
MC (Netherlands) 1 B.V. Willem Einthovenstraat 4 2342BH Oegstgeest Netherlands Netherlands Active Bronopol 200-143-0 52-51-7 - View substance registered dossier
THOR GmbH Landwehrstrasse 1 D-67346 Speyer Rheinland-Pfalz Germany Germany Active Bronopol 200-143-0 52-51-7 - View substance registered dossier
THOR ESPECIALIDADES, S.A. AVDA. DE LA INDUSTRIA, 1 - POL. IND. EL PLA 08297 CASTELLGALI BARCELONA Spain Spain Active Bronopol 200-143-0 52-51-7 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Bronopol 200-143-0 52-51-7 2019 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Bronopol 200-143-0 52-51-7 - View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
Life Technologies Europe BV Kwartsweg 2 2665 NN Bleiswijk Netherlands Netherlands Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
CJ Europe GmbH Unterschweinstiege 2-14 60549 Frankfurt am Main Germany Germany Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
NetSun EU B.V. Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands Netherlands Cease Manufacture Cysteine hydrochloride 200-157-7 52-89-1 2019 View substance registered dossier
Sigma-Aldrich Ireland Ltd Vale Road . Arklow Co. Wicklow Ireland Ireland Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany Germany Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
B-Lands Consulting (811700-5) OR of Shine Star (Hubei) Biological Engineering Co., Ltd 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active Cysteine hydrochloride 200-157-7 52-89-1 2021 View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active Cysteine hydrochloride 200-157-7 52-89-1 2016; 2017; 2018 View substance registered dossier
Global Life Sciences Solutions Austria GmbH & Co KG Kremplstraße 5 4061 Pasching Austria Austria Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
B-Lands Consulting (811703-4) OR of Wuhan Grand hoyo Co, . Ltd 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier
SAFC Biosciences Limited Smeaton Road, West Potway SP10 3LF Andover United Kingdom United Kingdom No longer Valid Cysteine hydrochloride 200-157-7 52-89-1 2021 View substance registered dossier
Sigma-Aldrich Company Limited The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom United Kingdom No longer Valid Cysteine hydrochloride 200-157-7 52-89-1 2021 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active Cysteine hydrochloride 200-157-7 52-89-1 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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