Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
Pyridinium, 1-[4-amino-6-[[4-[2-(4,8-disulfo-2-naphthalenyl)diazenyl]-8-sulfo-1-naphthalenyl]amino]-1,3,5-triazin-2-yl]-3-carboxy-, inner salt, sodium salt (1:?)
691-441-3 1316184-79-8 Active Full Joint ≥ 1 to < 10 tonnes 11-06-2018 View substance registered dossier
4-(1H-pyrazol-1-yl)piperidine hydrochloride
691-327-3 690261-87-1 Active Intermediate Joint Intermediate use only 22-05-2018 View substance registered dossier
N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
691-258-9 98626-61-0 Active Intermediate Individual Intermediate use only 11-10-2017 View substance registered dossier
7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, ethyl ester, (3S)-
691-244-2 106939-34-8 Active Intermediate Individual Intermediate use only 12-06-2014 View substance registered dossier
[No public or meaningful name is available]
691-232-7 - Active Intermediate Individual Intermediate use only 02-02-2012 View substance registered dossier
Morpholine, 4-(6-hydrazinyl-4-pyrimidinyl)-
691-196-2 5767-36-2 Active Intermediate Individual Intermediate use only 25-08-2014 View substance registered dossier
Benzenesulfonamide, 5-amino-2-methyl-
691-180-5 6973-09-7 Active Intermediate Joint Intermediate use only 26-11-2021 View substance registered dossier
Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-, hydrochloride (1:1)
691-142-8 76134-77-5 Active Intermediate Individual Intermediate use only 13-08-2015 View substance registered dossier
(R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid
691-120-8 486460-00-8 Active Intermediate Joint Intermediate use only 31-05-2022 View substance registered dossier
Carbamic acid, N-[(butylthio)thioxomethyl]-, butyl ester
691-061-8 1001320-38-2 Active Full Individual ≥ 0 to < 10 tonnes 30-09-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Everlight Europe B.V. Rivium Boulevard 224 2909LK Capelle a/d Ijssel Netherlands Netherlands Active Pyridinium, 1-[4-amino-6-[[4-[2-(4,8-disulfo-2-naphthalenyl)diazenyl]-8-sulfo-1-naphthalenyl]amino]-1,3,5-triazin-2-yl]-3-carboxy-, inner salt, sodium salt (1:?) 691-441-3 1316184-79-8 2014; 2015; 2016; 2018 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 4-(1H-pyrazol-1-yl)piperidine hydrochloride 691-327-3 690261-87-1 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide 691-258-9 98626-61-0 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, ethyl ester, (3S)- 691-244-2 106939-34-8 2014 View substance registered dossier
ARLANXEO Deutschland GmbH Alte Heerstraße 2 41540 Dormagen Germany Germany Active [No public or meaningful name is available] 691-232-7 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active Morpholine, 4-(6-hydrazinyl-4-pyrimidinyl)- 691-196-2 5767-36-2 - View substance registered dossier
Chemsafe Via Ribes 5 10010 Colleretto Giacosa (TO) Italy Italy Active Benzenesulfonamide, 5-amino-2-methyl- 691-180-5 6973-09-7 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Benzenesulfonamide, 5-amino-2-methyl- 691-180-5 6973-09-7 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active Benzenesulfonamide, 5-amino-2-methyl- 691-180-5 6973-09-7 2020 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-, hydrochloride (1:1) 691-142-8 76134-77-5 - View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Cytec Industries B.V. OR Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands Netherlands Active Carbamic acid, N-[(butylthio)thioxomethyl]-, butyl ester 691-061-8 1001320-38-2 2014; 2019 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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