Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1)
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(2S)-2-hydroxy-1-(1-pyrrolidinyl)-1-propanone
601-833-8 122151-38-6 Active Intermediate Individual Intermediate use only 24-01-2018 View substance registered dossier
(2S)-4-amino-2-hydroxy-butanoic acid
670-305-7 40371-51-5 Active Intermediate Individual Intermediate use only 27-01-2020 View substance registered dossier
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1)
695-797-0 93601-86-6 Active Intermediate Joint Intermediate use only 13-11-2018 View substance registered dossier
(2S)-but-3-yn-2-yl methanesulfonate
857-677-8 73647-37-7 Active Intermediate Individual Intermediate use only 24-07-2020 View substance registered dossier
(2S)-N-(2,6-dimethylphenyl)-1-propyl-piperidine-2-carboxamide
617-525-1 84057-95-4 Active Intermediate Individual Intermediate use only 11-10-2017 View substance registered dossier
(2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid
949-609-1 - Active Intermediate Joint Intermediate use only 29-04-2022 View substance registered dossier
(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid
617-180-7 80875-98-5 Active Intermediate Joint Intermediate use only 21-07-2022 View substance registered dossier
(2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid
800-213-6 1007881-21-1 Active Intermediate Individual Intermediate use only 07-11-2018 View substance registered dossier
(2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran
835-228-7 211801-54-6 Cease Manufacture Intermediate Individual Cease manufacture 05-03-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1) - - - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active (2S)-2-hydroxy-1-(1-pyrrolidinyl)-1-propanone 601-833-8 122151-38-6 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (2S)-4-amino-2-hydroxy-butanoic acid 670-305-7 40371-51-5 - View substance registered dossier
[Confidential] - - - (2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1) 695-797-0 93601-86-6 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (2S)-but-3-yn-2-yl methanesulfonate 857-677-8 73647-37-7 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2S)-N-(2,6-dimethylphenyl)-1-propyl-piperidine-2-carboxamide 617-525-1 84057-95-4 - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active (2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid 949-609-1 - 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid 949-609-1 - - View substance registered dossier
ORIL INDUSTRIE 13 rue Auguste Desgenétais 76210 BOLBEC France France Active (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid 617-180-7 80875-98-5 2019; 2020; 2021; 2022 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid 617-180-7 80875-98-5 2019 View substance registered dossier
DKSH France S.A. 1475 Quai du Rhone 01702 Miribel France France Active (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid 617-180-7 80875-98-5 - View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid 617-180-7 80875-98-5 - View substance registered dossier
LABORATORIOS SERVIER S.L. RIO JARAMA 59 45007 TOLEDO Spain Spain Active (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid 617-180-7 80875-98-5 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid 800-213-6 1007881-21-1 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran 835-228-7 211801-54-6 2021 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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