Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid
264-133-8 63422-71-9 Active Intermediate Joint Intermediate use only 08-05-2017 View substance registered dossier
(R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid
264-133-8 63422-71-9 Active Intermediate Individual Intermediate use only 21-08-2013 View substance registered dossier
(R)-cyclohex-3-enecarboxylic acid
634-674-8 5709-98-8 Active Intermediate Joint Intermediate use only 11-09-2017 View substance registered dossier
(R)-methyl(α-methylphenethyl)ammonium [R-(R*,R*)]-hydrogen tartrate
298-036-7 93777-08-3 Active Intermediate Joint Intermediate use only 06-10-2017 View substance registered dossier
(R)-quinuclidin-3-ol
246-857-6 25333-42-0 Active Intermediate Joint Intermediate use only 11-04-2022 View substance registered dossier
(R)-α-aminocyclohexa-1,4-diene-1-acetic acid
247-999-1 26774-88-9 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
(R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate
PHENETHYLAMMONIUM SALT OF FOSFOMYCIN
418-570-8 25383-07-7 Active Intermediate Joint Intermediate use only 22-05-2020 View substance registered dossier
(R)-β-aminophenethyl alcohol
260-287-5 56613-80-0 Active Intermediate Joint Intermediate use only 18-01-2021 View substance registered dossier
(R*,S*)-(±)-α-[1-(methylamino)ethyl]benzyl alcohol hydrochloride
205-153-9 134-71-4 Active Intermediate Joint Intermediate use only 30-07-2015 View substance registered dossier
(R*,S*)-(±)-α-[4-[2-(dimethylamino)ethoxy]phenyl]-β-ethyl-α-phenylphenethyl alcohol
278-718-0 77542-06-4 Active Intermediate Individual Intermediate use only 26-03-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
REACHLaw Ltd Vänrikinkuja 3 JK 21 02600 Espoo Finland Finland Active (R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid 264-133-8 63422-71-9 - View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active (R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid 264-133-8 63422-71-9 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-cyclohex-3-enecarboxylic acid 634-674-8 5709-98-8 - View substance registered dossier
[Confidential] - - - (R)-methyl(α-methylphenethyl)ammonium [R-(R*,R*)]-hydrogen tartrate 298-036-7 93777-08-3 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (R)-quinuclidin-3-ol 246-857-6 25333-42-0 2017 View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (R)-quinuclidin-3-ol 246-857-6 25333-42-0 - View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active (R)-quinuclidin-3-ol 246-857-6 25333-42-0 - View substance registered dossier
Centrient Pharmaceuticals Spain S.A. Calle Ripollès, no. 2 08130 Santa Perpètua de Mogoda (Barcelona) Spain Spain Active (R)-α-aminocyclohexa-1,4-diene-1-acetic acid 247-999-1 26774-88-9 - View substance registered dossier
LABIANA PHARMACEUTICALS S.L. Carrer Casanova, 27-31 08757 Corbera de Llobregat Spain Spain Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 - View substance registered dossier
Siemsgluss Ibérica, S.A. Pol. Ind. Sant Antoni, parcela 6, nave 2 08620 Sant Vicenç dels Horts Barcelona Spain Spain Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 - View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 2011; 2016; 2017 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 2011; 2020 View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 - View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active (R)-β-aminophenethyl alcohol 260-287-5 56613-80-0 2020; 2021 View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (R*,S*)-(±)-α-[1-(methylamino)ethyl]benzyl alcohol hydrochloride 205-153-9 134-71-4 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (R*,S*)-(±)-α-[4-[2-(dimethylamino)ethoxy]phenyl]-β-ethyl-α-phenylphenethyl alcohol 278-718-0 77542-06-4 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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