Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
4-(morpholin-4-yl)-1,2,5-thiadiazol-3(2H)-one
608-450-5 30165-97-0 Active Intermediate Joint Intermediate use only 12-08-2021 View substance registered dossier
4-(oxiran-2-ylmethoxy)-9H-carbazole
610-764-2 51997-51-4 Active Intermediate Joint Intermediate use only 20-02-2019 View substance registered dossier
4-(p-aminoanilino)-3-nitrobenzenesulphonic acid
205-175-9 135-11-5 Active Intermediate Joint Intermediate use only 12-04-2020 View substance registered dossier
4-(p-chlorophenyl)piperidin-4-ol
254-479-8 39512-49-7 Active Intermediate Individual Intermediate use only 20-12-2016 View substance registered dossier
4-(p-nitrophenylthio)aniline
202-957-1 101-59-7 Active Intermediate Joint Intermediate use only 14-05-2021 View substance registered dossier
4-(trans-4-Propylcyclohexyl)-1-bromobenzene
485-340-1 - Active Intermediate Joint Intermediate use only 19-11-2019 View substance registered dossier
4-(trans-4-propylcyclohexyl)acetophenone
4-(4-PROPYLCYCLOHEXYL)-ACETOPHENON
406-700-6 78531-61-0 Active Intermediate Joint Intermediate use only 11-12-2019 View substance registered dossier
4-(trifluoromethoxy)aniline
207-317-5 461-82-5 Active Intermediate Joint Intermediate use only 07-02-2022 View substance registered dossier
4-(α,α-dimethylbenzyl)phenol
209-968-0 599-64-4 Active Intermediate Joint Intermediate use only 10-07-2020 View substance registered dossier
4-[(2,5-dichlorophenyl)azo]-3-hydroxy-2-naphthoic acid
257-484-3 51867-77-7 Active Intermediate Joint Intermediate use only 10-04-2013 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active 4-(morpholin-4-yl)-1,2,5-thiadiazol-3(2H)-one 608-450-5 30165-97-0 - View substance registered dossier
PCAS Finland Oy Messukentänkatu 8 20210 TURKU Finland Finland Active 4-(morpholin-4-yl)-1,2,5-thiadiazol-3(2H)-one 608-450-5 30165-97-0 - View substance registered dossier
INKE, S.A. Area Industrial del Llobregat Argent, 1 08755 Castellbisbal Barcelona Spain Spain Active 4-(oxiran-2-ylmethoxy)-9H-carbazole 610-764-2 51997-51-4 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 4-(oxiran-2-ylmethoxy)-9H-carbazole 610-764-2 51997-51-4 - View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active 4-(oxiran-2-ylmethoxy)-9H-carbazole 610-764-2 51997-51-4 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active 4-(oxiran-2-ylmethoxy)-9H-carbazole 610-764-2 51997-51-4 2017 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 4-(oxiran-2-ylmethoxy)-9H-carbazole 610-764-2 51997-51-4 2017 View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 4-(p-aminoanilino)-3-nitrobenzenesulphonic acid 205-175-9 135-11-5 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active 4-(p-chlorophenyl)piperidin-4-ol 254-479-8 39512-49-7 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active 4-(p-nitrophenylthio)aniline 202-957-1 101-59-7 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 4-(p-nitrophenylthio)aniline 202-957-1 101-59-7 2021 View substance registered dossier
Kemikos s.r.l. Via Carolina Romani, 2/A 20091 Bresso (MI) Italy Italy Active 4-(p-nitrophenylthio)aniline 202-957-1 101-59-7 2019 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(trans-4-Propylcyclohexyl)-1-bromobenzene 485-340-1 - 2018; 2019 View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-(trans-4-Propylcyclohexyl)-1-bromobenzene 485-340-1 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(trans-4-propylcyclohexyl)acetophenone 406-700-6 78531-61-0 2010; 2013; 2017; 2019 View substance registered dossier
Chemservice GmbH - (K1C3) Herrnsheimer Hauptstrasse 1b 67550 Worms Germany Germany Cease Manufacture 4-(trifluoromethoxy)aniline 207-317-5 461-82-5 2020 View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active 4-(trifluoromethoxy)aniline 207-317-5 461-82-5 2022 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 4-(trifluoromethoxy)aniline 207-317-5 461-82-5 2020; 2022 View substance registered dossier
SHPP B.V. Plasticslaan 1 4612PX Bergen op Zoom Netherlands Netherlands Active 4-(α,α-dimethylbenzyl)phenol 209-968-0 599-64-4 - View substance registered dossier
SABIC Innovative Plastics BV Plasticslaan 1 4612 PX Bergen op Zoom Netherlands Netherlands Netherlands Active 4-(α,α-dimethylbenzyl)phenol 209-968-0 599-64-4 2012; 2015 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-[(2,5-dichlorophenyl)azo]-3-hydroxy-2-naphthoic acid 257-484-3 51867-77-7 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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