Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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(2,4-Difluorophenyl)(4-Fluorophenyl)methanone
813-638-7 80512-44-3 Active Intermediate Individual Intermediate use only 23-01-2018 View substance registered dossier
(2,5-dichloropentyl)ammonium chloride
263-758-3 62922-45-6 Active Intermediate Joint Intermediate use only 27-07-2018 View substance registered dossier
(2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate
433-520-5 82911-69-1 Active Intermediate Joint Intermediate use only 06-03-2020 View substance registered dossier
(2,6-xylyloxy) acetic acid
430-910-7 13335-71-2 Active Intermediate Joint Intermediate use only 14-06-2018 View substance registered dossier
(2-((2 S,3 S)-2-(( S)-3-( tert-butoxy)-2-(( S)-2-(( S)-4-( tert-butoxy)-2-(( S)-3-( tert-butoxy)-2-((2 S,3 R)-3-( tert-butoxy)-2-(( S)-2-((2 S,3 R)-3-( tert-butoxy)-2-(2-(( S)-5-( tert-butoxy)-2-(2-(( S)-3-(4-( tert-butoxy)phenyl)-2-(( tert-butoxycarbonyl)amino)propanamido)-2-methylpropanamido)-5-oxopentanamido)acetamido)butanamido)-3-phenylpropanamido)butanamido)propanamido)-4-oxobutanamido)-3-(4-( tert-butoxy)phenyl)propanamido)propanamido)-3-methylpentanamido)-2-methylpropanoyl)- L-leucine
955-183-8 - Active Intermediate Joint Intermediate use only 21-12-2021 View substance registered dossier
(2-(1-isopropyl-1H-pyrazol-5-yl)pyrid-3-yl)methanol hydrochloride (1:1)
941-991-8 - Active Intermediate Joint Intermediate use only 11-04-2018 View substance registered dossier
(2-bromophenyl)acetonitrile
243-091-4 19472-74-3 Active Intermediate Joint Intermediate use only 24-05-2018 View substance registered dossier
(2-butyl-5-nitrobenzofuran-3-yl)[4-(3-dibutylaminopropoxy)phenyl]methanone
BUTAMINONITRODARONE; SR33581
444-800-1 141645-23-0 Active Intermediate Individual Intermediate use only 22-11-2010 View substance registered dossier
(2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone
217-773-7 1951-26-4 Active Intermediate Joint Intermediate use only 13-04-2018 View substance registered dossier
(2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone
257-959-5 52490-15-0 Active Intermediate Joint Intermediate use only 05-04-2022 View substance registered dossier
(2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone
280-851-4 83790-87-8 Active Intermediate Joint Intermediate use only 27-04-2018 View substance registered dossier
(2-chloro-1,1-dimethylethyl)benzene
208-197-7 515-40-2 Active Intermediate Joint Intermediate use only 02-09-2021 View substance registered dossier
(2-chloropyrid-3-yl)methanol
690-999-5 42330-59-6 Active Intermediate Joint Intermediate use only 20-11-2017 View substance registered dossier
(2-ethoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide
250-002-2 30018-16-7 Active Intermediate Joint Intermediate use only 19-03-2018 View substance registered dossier
(2-ethoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide
250-002-2 30018-16-7 Active Intermediate Individual Intermediate use only 14-08-2013 View substance registered dossier
(2-hydroxyethyl)(3-hydroxypropyl)dimethylammonium chloride
278-860-3 78182-00-0 Cease Manufacture Intermediate Individual Cease manufacture 30-08-2011 View substance registered dossier
(2-hydroxypropyl)trimethylammonium chloride
219-183-5 2382-43-6 Active Intermediate Joint Intermediate use only 20-12-2016 View substance registered dossier
(2-methylpropyl)lithium;isobutyllithium
440-620-2 920-36-5 Active Intermediate Individual Intermediate use only 17-12-2010 View substance registered dossier
(2-oxo-2-phenylmethoxyethyl) 2-[2-(2,6-dichloroanilino)phenyl]acetate
600-104-1 100499-89-6 Active Intermediate Joint Intermediate use only 15-12-2020 View substance registered dossier
(20R,25R)-spirost-5-en-3β-ol
208-134-3 512-04-9 Active Intermediate Joint Intermediate use only 04-08-2021 View substance registered dossier
(22S)-22-carboxy-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic acid
815-717-1 1169630-40-3 Active Intermediate Individual Intermediate use only 29-05-2019 View substance registered dossier
(2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE
610-496-6 500292-86-4 Active Intermediate Joint Intermediate use only 28-05-2018 View substance registered dossier
(2E)-3-[(tert-butoxycarbonyl)(propan-2-yl)amino]-2-(4-chlorophenyl)prop-2-enoic acid
813-178-7 1489004-27-4 Active Intermediate Joint Intermediate use only 24-06-2020 View substance registered dossier
(2E)-3-Phenylacrylaldehyde
604-377-8 14371-10-9 Active Intermediate Joint Intermediate use only 09-11-2021 View substance registered dossier
(2E)-4,4,4-trifluorobut-2-en-1-ol
835-846-7 83706-94-9 Active Intermediate Joint Intermediate use only 18-07-2019 View substance registered dossier
(2E)-N,N-diethyl-3,7-dimethyl-octa-2,6-dien-1-amine
814-576-3 40267-53-6 Active Intermediate Joint Intermediate use only 23-10-2020 View substance registered dossier
(2E,4E)-2,4-decadienoic acid
250-149-2 30361-33-2 Active Intermediate Joint Intermediate use only 17-04-2020 View substance registered dossier
(2E,4E,7S)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid, ammonium salt (1:1)
619-006-5 942519-41-7 Active Intermediate Joint Intermediate use only 06-04-2018 View substance registered dossier
(2E,4R)-5-{[1,1’-biphenyl]-4-yl}-4-[(tert-butoxycarbonyl)amino]-2-methylpent-2-enoic acid
695-654-2 1012341-48-8 Active Intermediate Individual Intermediate use only 03-09-2014 View substance registered dossier
(2R)-1-(2,4-difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one
823-704-7 126918-17-0 Active Intermediate Joint Intermediate use only 07-04-2018 View substance registered dossier
(2R)-1-morpholino-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one
819-998-1 135270-08-5 Active Intermediate Joint Intermediate use only 19-01-2018 View substance registered dossier
(2R)-1-{5-Amino-2-[1-(benzyloxy)-2-méthyl-2-propanyl]-6-fluoro-1H-indol-1-yl}-3-(benzyloxy)-2-propanol
811-584-9 1294504-67-8 Active Intermediate Joint Intermediate use only 26-11-2021 View substance registered dossier
(2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid
951-764-5 - Active Intermediate Individual Intermediate use only 15-01-2020 View substance registered dossier
(2R)-2-aminobutan-1-ol L-tartrate monohydrate
814-787-0 153078-05-8 Active Intermediate Joint Intermediate use only 05-04-2018 View substance registered dossier
(2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride
700-669-5 2788-28-5 Active Intermediate Joint Intermediate use only 01-08-2019 View substance registered dossier
(2R)-[(methoxycarbonyl)amino](phenyl)acetic acid
694-843-7 50890-96-5 Active Intermediate Individual Intermediate use only 13-09-2021 View substance registered dossier
(2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1)
947-841-8 - Active Intermediate Individual Intermediate use only 16-05-2018 View substance registered dossier
(2R*)-1-[4-(benzyloxy)phenyl]-1-oxo-N-[(2R*)-1-phenoxypropan-2-yl]propan-2-aminium chloride
867-647-6 1179802-09-5 Active Intermediate Joint Intermediate use only 21-07-2021 View substance registered dossier
(2R,3R)-2,3-Dihydroxybutanedioic acid-(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1)
947-840-2 - Active Intermediate Individual Intermediate use only 16-05-2018 View substance registered dossier
(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate
815-196-0 1175536-50-1 Active Intermediate Joint Intermediate use only 31-08-2017 View substance registered dossier
(2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate
4-AA; AOSA; AZETIDONE-KANEKA; GR91990X
408-050-9 76855-69-1 Active Intermediate Individual Intermediate use only 20-09-2012 View substance registered dossier
(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-[1,2,4]triazol-1-yl-thiobutyramide
609-299-8 368421-58-3 Active Intermediate Individual Intermediate use only 16-10-2017 View substance registered dossier
(2R,3R)-3-(3-(Benzyloxy)phenyl-2-methylpentanoic acid
805-624-4 1367878-84-9 Active Intermediate Joint Intermediate use only 28-05-2020 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid
948-743-8 - Active Intermediate Joint Intermediate use only 04-10-2018 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate dihydrochloride
948-534-1 1639208-51-7 Active Intermediate Joint Intermediate use only 20-08-2018 View substance registered dossier
(2R,3R,4R)-3,4-Bis(benzyloxy)-2-((benzyloxy)methyl)-5-methoxytetrahydrofuran
857-987-3 64363-77-5 Active Intermediate Joint Intermediate use only 01-09-2020 View substance registered dossier
(2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolane-2-carbonitrile
856-564-0 1355357-49-1 Active Intermediate Joint Intermediate use only 09-07-2020 View substance registered dossier
(2R,3R,4R,5R)-5-(2-Amino-6-chloro-9h-purin-9-yl)-2-[(4-chlorobenzoyloxy)methyl]-4-fluoro-4-methyloxolan-3-yl 4-chlorobenzoate
875-019-8 1294481-82-5 Active Intermediate Joint Intermediate use only 27-10-2021 View substance registered dossier
(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile
857-885-9 1191237-69-0 Active Intermediate Joint Intermediate use only 07-09-2020 View substance registered dossier
(2R,3S)-N-(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide hydrochloride
425-260-6 244634-31-9 Active Intermediate Joint Intermediate use only 10-04-2012 View substance registered dossier
(2R,3S,4R)-2-(Hydroxymethyl)-5-methoxytetrahydrofuran-3,4-diol
857-672-0 13039-63-9 Active Intermediate Joint Intermediate use only 01-09-2020 View substance registered dossier
(2R,3S,4R,5R)-2,3,4,6-tetrakis(benzyloxy)-5-hydroxy-1-(4-methylpiperazin-1-yl) hexan-1-one
829-550-7 1431329-04-2 Active Intermediate Joint Intermediate use only 05-05-2020 View substance registered dossier
(2R,3S,4R,5R)-2,3,4,6-tetrakis(benzyloxy)-5-hydroxy-1-(4-methylpiperazin-1-yl) hexan-1-one
829-550-7 1431329-04-2 Active Intermediate Individual Intermediate use only 18-09-2018 View substance registered dossier
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-erythro-hexopyranosyl-4-ulose)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl 2-O-[(benzyloxy)carbonyl]-3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside trifluoroacetate (1:2)
953-335-8 1210740-88-7 Active Intermediate Joint Intermediate use only 30-03-2021 View substance registered dossier
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-13-{[(3S,4S,6R,8R)-8-methoxy-4,8-dimethyl-1,5-dioxaspiro[2.5]oct-6-yl]oxy}-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl 3,4,6-trideoxy-3-(dimethylamino)--D-xylo-hexopyranoside
953-425-7 217500-75-9 Active Intermediate Joint Intermediate use only 28-01-2021 View substance registered dossier
(2S)-1,1,2-triphenylethane-1,2-diol
624-788-6 108998-83-0 Active Intermediate Joint Intermediate use only 14-06-2018 View substance registered dossier
(2S)-1,1-bis(4-fluorophenyl)propan-2-yl L-alaninate hydrochloride
- - Active Intermediate Joint Intermediate use only 24-06-2022 View substance registered dossier
(2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene
214-494-2 1135-66-6 Active Intermediate Joint Intermediate use only 07-01-2020 View substance registered dossier
(2S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile
807-388-8 207557-35-5 Active Intermediate Joint Intermediate use only 25-04-2019 View substance registered dossier
(2S)-1-(2-phenylacetyl)pyrrolidine-2-carboxylic acid
928-037-6 2752-38-7 Active Intermediate Joint Intermediate use only 26-01-2018 View substance registered dossier
(2S)-1-[(tert-butyl)oxycarbonyl]-2-methylpyrrolidine-2-carboxylic acid
813-635-0 103336-06-7 Active Intermediate Joint Intermediate use only 07-12-2018 View substance registered dossier
(2S)-2-(benzyloxy)propanal
617-235-5 81445-44-5 Active Intermediate Individual Intermediate use only 08-10-2018 View substance registered dossier
(2S)-2-[(4-Chlorobenzoyl)oxy]propanoic acid
- - Active Intermediate Joint Intermediate use only 20-12-2017 View substance registered dossier
(2S)-2-[(8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propanal
861-038-9 3986-89-8 Active Intermediate Joint Intermediate use only 02-12-2020 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 82717-96-2 Active Intermediate Individual Intermediate use only 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 82717-96-2 Cease Manufacture Intermediate Individual Cease manufacture 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 82717-96-2 Active Intermediate Individual Intermediate use only 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 82717-96-2 Active Intermediate Joint Intermediate use only 28-01-2019 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 82717-96-2 Active Intermediate Joint Intermediate use only 26-02-2020 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoic acid
617-393-5 82834-12-6 Active Intermediate Joint Intermediate use only 24-11-2021 View substance registered dossier
(2S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropanoic acid;hydrochloride
611-205-5 5486-79-3 Active Intermediate Joint Intermediate use only 12-09-2019 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1)
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(2S)-2-hydroxy-1-(1-pyrrolidinyl)-1-propanone
601-833-8 122151-38-6 Active Intermediate Individual Intermediate use only 24-01-2018 View substance registered dossier
(2S)-4-amino-2-hydroxy-butanoic acid
670-305-7 40371-51-5 Active Intermediate Individual Intermediate use only 27-01-2020 View substance registered dossier
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1)
695-797-0 93601-86-6 Active Intermediate Joint Intermediate use only 13-11-2018 View substance registered dossier
(2S)-but-3-yn-2-yl methanesulfonate
857-677-8 73647-37-7 Active Intermediate Individual Intermediate use only 24-07-2020 View substance registered dossier
(2S)-N-(2,6-dimethylphenyl)-1-propyl-piperidine-2-carboxamide
617-525-1 84057-95-4 Active Intermediate Individual Intermediate use only 11-10-2017 View substance registered dossier
(2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid
949-609-1 - Active Intermediate Joint Intermediate use only 29-04-2022 View substance registered dossier
(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid
617-180-7 80875-98-5 Active Intermediate Joint Intermediate use only 24-11-2021 View substance registered dossier
(2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid
800-213-6 1007881-21-1 Active Intermediate Individual Intermediate use only 07-11-2018 View substance registered dossier
(2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran
835-228-7 211801-54-6 Cease Manufacture Intermediate Individual Cease manufacture 05-03-2019 View substance registered dossier
(2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-ol
667-304-9 6564-72-3 Active Intermediate Joint Intermediate use only 31-12-2020 View substance registered dossier
(2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid — methyl {(4S)-8-fluoro-2-[4-(3methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4yl}acetate — ethyl acetate (1:1:1)
947-432-4 - Active Intermediate Joint Intermediate use only 04-09-2020 View substance registered dossier
(2S,3S)-2,3-Dihydroxysuccinic acid - (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide (1:2)
954-871-5 - Active Intermediate Individual Intermediate use only 19-08-2021 View substance registered dossier
(2S,3S)-di-tert-butyl 3-ethyl-4-oxopyrrolidine-1,2-dicarboxylate
942-044-1 - Active Intermediate Joint Intermediate use only 27-02-2017 View substance registered dossier
(2S,3S,4R)-3-ethyl-4-hydroxy-2-(methoxycarbonyl)pyrrolidinium 4-methylbenzenesulfonate
813-641-3 1799733-43-9 Active Intermediate Joint Intermediate use only 18-04-2018 View substance registered dossier
(2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol succinate
938-481-2 - Active Intermediate Joint Intermediate use only 31-10-2018 View substance registered dossier
(2S,4aR)-1,1,5,5-tetramethyl-1,3,4,5,6,7-hexahydro-2H-2,4a-methanonaphthalen-7-ol
942-036-8 645413-57-6 Active Intermediate Joint Intermediate use only 01-07-2020 View substance registered dossier
(2S,4Z)-5-amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one;5-amino-[2S-di(methylphenyl)amino]-1,6-diphenyl-4Z-hexen-3-one
423-090-7 156732-13-7 Active Intermediate Joint Intermediate use only 12-06-2018 View substance registered dossier
(2S,5S,32S)-5-{[(5S,8S,11S,14S,17S)-11-[(2R)-BUTAN-2-YL]-8-{4-[(TERT-BUTOXYCARBONYL)AMINO]BUTYL}-5-(2-TERT-BUTOXY-2-OXOETHYL)-1-(9H-FLUOREN-9-YL)-14-METHYL-3,6,9,12,15,18-HEXAOXO-17-{3-OXO-3-[(TRIPHENYLMETHYL)AMINO]PROPYL}-2-OXA-4,7,10,13,16-PENTAAZAOCTADECAN-18-YL]AMINO}-32-(TERT-BUTOXYCARBONYL)-2,55,55-TRIMETHYL-4,11,20,29,34,53-HEXAOXO-13,16,22,25,54-PENTAOXA-3,10,19,28,33-PENTAAZAHEXAPENTACONTAN-1-OIC ACID
954-943-6 - Active Intermediate Individual Intermediate use only 02-09-2021 View substance registered dossier
(2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
255-799-0 42399-49-5 Active Intermediate Joint Intermediate use only 19-10-2018 View substance registered dossier
(2S-cis)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
255-795-9 42399-40-6 Active Intermediate Joint Intermediate use only 09-04-2018 View substance registered dossier
(2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid
279-393-8 80082-65-1 Active Intermediate Joint Intermediate use only 23-02-2018 View substance registered dossier
(2Z)-7-chloro-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid
618-065-4 877674-77-6 Active Intermediate Joint Intermediate use only 13-09-2017 View substance registered dossier
(2α,6α,11R*)-3-benzyl-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol hydrobromide
248-106-8 26918-40-1 Active Intermediate Joint Intermediate use only 26-04-2018 View substance registered dossier
(3,3-diethoxy-1-propenyl)benzene
230-467-8 7148-78-9 Active Intermediate Joint Intermediate use only 14-01-2022 View substance registered dossier
(3,4-diethoxyphenyl)acetonitrile
248-479-7 27472-21-5 Active Intermediate Joint Intermediate use only 06-01-2022 View substance registered dossier
(3-((6-Chlorohexyl)thio)propyl)triethoxysilane and Hexamethylen-1,6-dithio-bis((3-triethoxysilyl) propane)
951-684-0 - Active Intermediate Joint Intermediate use only 26-02-2021 View substance registered dossier
(3-acetyloxy-5-carbonochloridoylphenyl) acetate
855-283-0 39192-49-9 Active Intermediate Joint Intermediate use only 05-06-2020 View substance registered dossier
(3-bromopropyl)benzene
211-294-7 637-59-2 Active Intermediate Joint Intermediate use only 14-05-2018 View substance registered dossier
(3-Carboxyprop-1-yl)(triphenyl)phosphonium bromide
629-007-2 17857-14-6 Active Intermediate Joint Intermediate use only 14-12-2021 View substance registered dossier
(3-chloro-2-hydroxypropyl)dimethyloctadecylammonium chloride
221-083-1 3001-63-6 Active Intermediate Individual Intermediate use only 22-07-2021 View substance registered dossier
(3-chloro-2-hydroxypropyl)dodecyldimethylammonium chloride
255-578-9 41892-01-7 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
(3-chloro-2-hydroxypropyl)trimethylammonium chloride
222-048-3 3327-22-8 Active Intermediate Joint Intermediate use only 29-07-2021 View substance registered dossier
(3-chloro-2-hydroxypropyl)trimethylammonium chloride
222-048-3 3327-22-8 Active Intermediate Individual Intermediate use only 08-01-2014 View substance registered dossier
(3-chloroprop-1-enyl)benzene
220-246-4 2687-12-9 Active Intermediate Joint Intermediate use only 30-05-2018 View substance registered dossier
(3-chloropropyl)benzene
203-210-2 104-52-9 Active Intermediate Joint Intermediate use only 10-07-2019 View substance registered dossier
(3-chloropropyl)diethoxymethylsilane
236-828-6 13501-76-3 Active Intermediate Joint Intermediate use only 04-05-2015 View substance registered dossier
(3-chloropropyl)methoxydimethylsilane
242-055-5 18171-14-7 Active Intermediate Joint Intermediate use only 15-02-2018 View substance registered dossier
(3-cyano-2-hydroxypropyl)trimethylammonium chloride
242-684-5 18933-33-0 Active Intermediate Joint Intermediate use only 03-10-2019 View substance registered dossier
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl methanesulfonate
700-367-3 35130-97-3 Cease Manufacture Intermediate Individual Cease manufacture 09-02-2010 View substance registered dossier
(3-methoxyphenyl)acetonitrile
243-428-5 19924-43-7 Active Intermediate Joint Intermediate use only 19-05-2017 View substance registered dossier
(3-methyl-1,4-dioxo-2-naphthyl) 4-nitrobenzoate
604-586-4 14748-93-7 Active Intermediate Joint Intermediate use only 10-07-2019 View substance registered dossier
(3-Methyl-but-2-enyloxy)-benzol
846-080-8 14309-15-0 Active Intermediate Individual Intermediate use only 01-07-2020 View substance registered dossier
(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,2R,4R)-4-amino-2-hydroxycyclohexyl)thio)acetate
813-124-2 1061337-51-6 Active Intermediate Individual Intermediate use only 25-09-2018 View substance registered dossier
(3aR,4R,6R,6aR)-4-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-6-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-4-carbonitrile
857-886-4 1191237-80-5 Active Intermediate Joint Intermediate use only 07-09-2020 View substance registered dossier
(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one
608-721-8 32233-40-2 Active Intermediate Joint Intermediate use only 18-04-2018 View substance registered dossier
(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl[(methylsulfonyl)oxy]acetate
700-396-1 60924-38-1 Cease Manufacture Intermediate Individual Cease manufacture 09-02-2010 View substance registered dossier
(3aα,4α,7α,7aα)-octahydro-4,7-methano-1H-indene
220-586-3 2825-83-4 Active Intermediate Joint Intermediate use only 10-04-2018 View substance registered dossier
(3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5)
931-336-4 - Cease Manufacture Intermediate Individual Cease manufacture 13-09-2012 View substance registered dossier
(3E)-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pent-3-en-2-one
948-348-0 208034-56-4 Active Intermediate Joint Intermediate use only 10-09-2019 View substance registered dossier
(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-ol
810-303-7 459-89-2 Active Intermediate Joint Intermediate use only 25-09-2018 View substance registered dossier
(3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-amine
836-285-0 125349-37-3 Active Intermediate Joint Intermediate use only 02-03-2021 View substance registered dossier
(3R)-2,3-dihydro-1,1,3-trimethyl-1H-Inden-4-amine-(2S,3S)-2,3-dihydroxybutanedioate
701-382-8 - Active Intermediate Joint Intermediate use only 09-04-2021 View substance registered dossier
(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one hydrochloride
813-550-9 486459-71-6 Active Intermediate Joint Intermediate use only 28-02-2022 View substance registered dossier
(3R)-3-methyl-5-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydronaphthalen-1-yl]pent-1-en-3-ol
637-366-1 596-85-0 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
(3R)-3-methylpiperazin-2-one
693-438-2 922178-61-8 Active Intermediate Individual Intermediate use only 30-05-2021 View substance registered dossier
(3R)-4[(2.4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one
- - Active Intermediate Individual Intermediate use only 21-03-2022 View substance registered dossier
(3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diyl bis(4-hydroxybenzoate)
606-059-4 185756-31-4 Active Intermediate Joint Intermediate use only 13-12-2017 View substance registered dossier
(3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol
856-563-5 1355049-94-3 Active Intermediate Joint Intermediate use only 24-08-2020 View substance registered dossier
(3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one
851-368-1 55094-52-5 Active Intermediate Joint Intermediate use only 10-09-2020 View substance registered dossier
(3R,4R,5R)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolan-2-ol
857-989-4 16838-89-4 Active Intermediate Joint Intermediate use only 01-09-2020 View substance registered dossier
(3R,4R,5S)-4-amino-5-azido-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester
805-634-9 204255-04-9 Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
(3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-3-carboxylic acid
820-324-3 1428243-24-6 Active Intermediate Joint Intermediate use only 23-03-2018 View substance registered dossier
(3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid
205-334-2 138-59-0 Active Intermediate Joint Intermediate use only 01-10-2019 View substance registered dossier
(3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
918-279-0 - Active Intermediate Joint Intermediate use only 26-04-2017 View substance registered dossier
(3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one
700-290-5 63968-64-9 Active Intermediate Individual Intermediate use only 15-11-2012 View substance registered dossier
(3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate
603-817-6 134395-00-9 Active Intermediate Joint Intermediate use only 28-09-2017 View substance registered dossier
(3R,6S)-1-benzyl-6-methylpiperidin-3-amine acetyl-L-leucinate [1:1]
840-203-9 2295746-51-7 Active Intermediate Joint Intermediate use only 24-11-2020 View substance registered dossier
(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate
228-502-7 6283-74-5 Active Intermediate Joint Intermediate use only 21-01-2022 View substance registered dossier
(3S)-3,7-dimethylocta-1,6-dien-1-yl acetate
946-529-9 1439355-19-7 Active Intermediate Joint Intermediate use only 24-01-2018 View substance registered dossier
(3S)-3-hydroxypyrrolidin-2-one
676-349-3 34368-52-0 Active Intermediate Individual Intermediate use only 12-11-2019 View substance registered dossier
(3S)-3-thiophen-2-ylsulfanylbutanoic acid
948-811-7 133359-80-5 Active Intermediate Joint Intermediate use only 23-10-2018 View substance registered dossier
(3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate
950-060-5 - Active Intermediate Joint Intermediate use only 15-01-2020 View substance registered dossier
(3S,1R)-3-N-Boc-aminocyclopentan-1-ol
807-383-0 167465-99-8 Active Intermediate Joint Intermediate use only 04-05-2018 View substance registered dossier
(3S,3S’)-Dineopentyl 4,4’-disulfanediylbis(3-(benzyloxycarbonylamino)butane-1-sulfonate
954-955-1 - Active Intermediate Joint Intermediate use only 27-09-2021 View substance registered dossier
(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide
420-380-5 136465-81-1 Cease Manufacture Intermediate Individual Cease manufacture 29-10-2012 View substance registered dossier
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine
929-011-7 - Active Intermediate Joint Intermediate use only 20-04-2018 View substance registered dossier
(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine
924-787-3 110429-36-2 Active Intermediate Joint Intermediate use only 08-03-2021 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 16-05-2018 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 12-07-2013 View substance registered dossier
(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone
444-350-6 133413-70-4 Active Intermediate Joint Intermediate use only 24-09-2019 View substance registered dossier
(3S,6S,7R,8R)-8-Benzyl-3-{[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]amino}-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl 2-methylpropanoate
844-009-5 167173-85-5 Active Intermediate Joint Intermediate use only 04-02-2022 View substance registered dossier
(3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile
828-107-5 118316-12-4 Active Intermediate Joint Intermediate use only 05-09-2018 View substance registered dossier
(3β)-17-(1,1,1-trifluoromethanesulfonate)-Androsta-5,16-diene-3,17-diol, 3-(2,2,2-trifluoroacetate)
840-627-4 1802323-89-2 Active Intermediate Joint Intermediate use only 26-06-2019 View substance registered dossier
(3β)-3-[(2,2,2-trifluoroacetyl)oxy]-Androst-5-en-17-one
840-626-9 3798-17-2 Active Intermediate Joint Intermediate use only 26-06-2019 View substance registered dossier
(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-yl butyrate
250-567-5 31316-20-8 Active Intermediate Joint Intermediate use only 24-01-2022 View substance registered dossier
(4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone
700-338-5 50372-61-7 Active Intermediate Joint Intermediate use only 05-10-2016 View substance registered dossier
(4-(3,4-dichloro-phenyl)-3,4-dihydro-2H-naphthalen-1-ylidene)-methyl-amide
455-240-2 - Active Intermediate Joint Intermediate use only 03-03-2022 View substance registered dossier
(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
613-265-8 63590-64-7 Active Intermediate Joint Intermediate use only 25-07-2018 View substance registered dossier
(4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile
262-792-6 61437-85-2 Active Intermediate Joint Intermediate use only 09-03-2018 View substance registered dossier
(4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride
816-907-7 1294454-93-5 Cease Manufacture Intermediate Joint Cease manufacture 28-05-2020 View substance registered dossier
(4-carboxybutyl)triphenylphosphonium bromide
241-782-5 17814-85-6 Active Intermediate Joint Intermediate use only 15-12-2015 View substance registered dossier
(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone
695-300-7 1103738-30-2 Active Intermediate Joint Intermediate use only 24-11-2020 View substance registered dossier
(4-chlorophenyl)hydrazine
214-029-3 1073-69-4 No longer Valid Intermediate Individual No longer valid 13-11-2013 View substance registered dossier
(4-chlorophenyl)hydrazine
214-029-3 1073-69-4 Active Intermediate Individual Intermediate use only 28-09-2010 View substance registered dossier
(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid
826-639-2 1817776-86-5 Active Intermediate Joint Intermediate use only 20-07-2020 View substance registered dossier
(4-nitrophenyl)methanesulfonyl chloride
609-806-2 4025-75-6 Active Intermediate Individual Intermediate use only 18-12-2019 View substance registered dossier
(4-phenylbutyl)phosphinic acid
420-450-5 86552-32-1 Active Intermediate Joint Intermediate use only 09-12-2013 View substance registered dossier
(4-pyridylmethyl)amine
223-092-6 3731-53-1 Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
(4-pyridylthio)acetyl chloride hydrochloride
248-348-4 27230-51-9 Active Intermediate Joint Intermediate use only 25-10-2021 View substance registered dossier
(4-tert-butyl-2,6-dimethylphenyl)acetonitrile
284-183-4 84803-57-6 Active Intermediate Joint Intermediate use only 30-07-2015 View substance registered dossier
(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Acetyl-5-hydroxy-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one
680-670-4 13649-88-2 Active Intermediate Joint Intermediate use only 10-08-2021 View substance registered dossier
(4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one
941-406-6 1391712-50-7 Active Intermediate Joint Intermediate use only 08-01-2019 View substance registered dossier
(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid
849-166-3 83841-00-3 Active Intermediate Joint Intermediate use only 18-05-2021 View substance registered dossier
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine
926-346-0 - Active Intermediate Joint Intermediate use only 10-11-2017 View substance registered dossier
(4R,12aS)-7-Benzyloxy-N-[(2,4-difluorophenyl)methyl]-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
809-887-6 1206102-11-5 Active Intermediate Individual Intermediate use only 27-06-2019 View substance registered dossier
(4R,4aS,7aR,12bS)-3-(ethoxycarbonyl)-7-oxo-1,2,3,4,7,7a-hexahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diyl diacetate
955-282-6 2387639-94-1 Active Intermediate Joint Intermediate use only 15-12-2021 View substance registered dossier
(4R,4aS,7aR,12bS)-3-methyl-7-oxo-2,3,4,4a,7,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diyl diacetate
875-213-2 50798-31-7 Active Intermediate Joint Intermediate use only 03-11-2021 View substance registered dossier
(4R,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol
604-572-8 147128-77-6 Active Intermediate Joint Intermediate use only 06-09-2018 View substance registered dossier
(4S)-2-(4-bromophenyl)-4-isopropyl-3-pentanoyl-1,3-oxazolidin-5-one
700-586-4 852212-81-8 Active Intermediate Individual Intermediate use only 10-05-2011 View substance registered dossier
(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
848-798-7 272778-12-8 Active Intermediate Joint Intermediate use only 15-06-2020 View substance registered dossier
(4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate
947-346-7 - Active Intermediate Individual Intermediate use only 22-10-2021 View substance registered dossier
(4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide
623-314-5 98674-86-3 Active Intermediate Joint Intermediate use only 26-03-2018 View substance registered dossier
(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide
807-123-6 154127-42-1 No longer Valid Intermediate Individual No longer valid 29-05-2018 View substance registered dossier
(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide
807-123-6 154127-42-1 Active Intermediate Joint Intermediate use only 23-03-2022 View substance registered dossier
(4S,4aR,5aR,6R,6aR,6bS,7S,9aS,11aS,11bR)-6-hydroxy-9a,11b-dimethyl-9-oxohexadeca hydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-4,7-diyl bis(2,2-dimethylpropanoate)
825-705-8 1235460-56-6 Active Intermediate Joint Intermediate use only 17-07-2018 View substance registered dossier
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)
940-053-5 - Active Intermediate Joint Intermediate use only 19-01-2017 View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
617-177-0 808-26-4 Active Intermediate Joint Intermediate use only 13-09-2018 View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
811-441-0 1035654-66-0 Active Intermediate Joint Intermediate use only 27-11-2019 View substance registered dossier
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrochloride
611-780-2 59046-78-5 Active Intermediate Individual Intermediate use only 14-05-2018 View substance registered dossier
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 4-chlorobenzene-1-sulfonic acid
618-775-4 916439-93-5 Active Intermediate Joint Intermediate use only 22-12-2017 View substance registered dossier
(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate
947-931-7 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid)
925-915-0 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonyl chloride, 4-(acetylethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide,
824-717-0 403848-30-6 Active Intermediate Joint Intermediate use only 05-06-2018 View substance registered dossier
(4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide
947-800-4 - Active Intermediate Joint Intermediate use only 21-06-2018 View substance registered dossier
(4S-trans)-N-(5,6-diidro-6-metil-7,7-diossido-4Htieno[2,3-b]tiopiran-4-il)-acetammide
604-558-1 147086-83-7 Active Intermediate Joint Intermediate use only 09-03-2018 View substance registered dossier
(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
700-141-4 117570-53-3 Cease Manufacture Intermediate Individual Cease manufacture 22-06-2010 View substance registered dossier
(5-bromothiophen-2-yl)-phenylmethanone
608-584-4 31161-46-3 Active Intermediate Joint Intermediate use only 14-02-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Stewardship Chemicals 40 Długosza 67 43-188 Orzesze Poland Poland Active (2,4-Difluorophenyl)(4-Fluorophenyl)methanone 813-638-7 80512-44-3 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (2,5-dichloropentyl)ammonium chloride 263-758-3 62922-45-6 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (2,5-dichloropentyl)ammonium chloride 263-758-3 62922-45-6 - View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany Germany Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 2010; 2013; 2020 View substance registered dossier
Chemical and Biopharmaceutical Laboratories of Patras S.A. Industrial area of Patras, Building block 1 25018 Patras Greece Greece Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate 433-520-5 82911-69-1 - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (2,6-xylyloxy) acetic acid 430-910-7 13335-71-2 2011; 2018 View substance registered dossier
[Confidential] - - - (2-((2 S,3 S)-2-(( S)-3-( tert-butoxy)-2-(( S)-2-(( S)-4-( tert-butoxy)-2-(( S)-3-( tert-butoxy)-2-((2 S,3 R)-3-( tert-butoxy)-2-(( S)-2-((2 S,3 R)-3-( tert-butoxy)-2-(2-(( S)-5-( tert-butoxy)-2-(2-(( S)-3-(4-( tert-butoxy)phenyl)-2-(( tert-butoxycarbonyl)amino)propanamido)-2-methylpropanamido)-5-oxopentanamido)acetamido)butanamido)-3-phenylpropanamido)butanamido)propanamido)-4-oxobutanamido)-3-(4-( tert-butoxy)phenyl)propanamido)propanamido)-3-methylpentanamido)-2-methylpropanoyl)- L-leucine 955-183-8 - - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (2-(1-isopropyl-1H-pyrazol-5-yl)pyrid-3-yl)methanol hydrochloride (1:1) 941-991-8 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2-bromophenyl)acetonitrile 243-091-4 19472-74-3 - View substance registered dossier
ACETO GmbH Hans-Henny-Jahnn-Weg 51 22085 Hamburg Germany Germany Active (2-bromophenyl)acetonitrile 243-091-4 19472-74-3 - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active (2-bromophenyl)acetonitrile 243-091-4 19472-74-3 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-butyl-5-nitrobenzofuran-3-yl)[4-(3-dibutylaminopropoxy)phenyl]methanone 444-800-1 141645-23-0 2010 View substance registered dossier
Arevipharma GmbH Meißner Straße 35 01445 Radebeul Saxony Germany Germany Active (2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone 217-773-7 1951-26-4 - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone 217-773-7 1951-26-4 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active (2-butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone 217-773-7 1951-26-4 2017 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 2017; 2018 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 2017 View substance registered dossier
Asambly Europe Company Limited Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland Ireland Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone 257-959-5 52490-15-0 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone 280-851-4 83790-87-8 - View substance registered dossier
[Confidential] - - - (2-chloro-1,1-dimethylethyl)benzene 208-197-7 515-40-2 - View substance registered dossier
Globalquimia, S.L.U. Avenida Diagonal, 519, 1º 1ª 08029 Barcelona Spain Spain Spain Active (2-chloro-1,1-dimethylethyl)benzene 208-197-7 515-40-2 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (2-chloropyrid-3-yl)methanol 690-999-5 42330-59-6 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (2-ethoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide 250-002-2 30018-16-7 - View substance registered dossier
[Confidential] - - - (2-ethoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide 250-002-2 30018-16-7 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture (2-hydroxyethyl)(3-hydroxypropyl)dimethylammonium chloride 278-860-3 78182-00-0 2020 View substance registered dossier
[Confidential] - - - (2-hydroxypropyl)trimethylammonium chloride 219-183-5 2382-43-6 - View substance registered dossier
Albemarle Germany GmbH Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany Germany Active (2-methylpropyl)lithium;isobutyllithium 440-620-2 920-36-5 2010 View substance registered dossier
RANKE QUIMICA S.A. Ctra. Nacional II, Km 593 08740 Sant Andreu de la Barca Barcelona Spain Spain Active (2-oxo-2-phenylmethoxyethyl) 2-[2-(2,6-dichloroanilino)phenyl]acetate 600-104-1 100499-89-6 2018; 2020 View substance registered dossier
Arevipharma GmbH Meißner Straße 35 01445 Radebeul Saxony Germany Germany Active (20R,25R)-spirost-5-en-3β-ol 208-134-3 512-04-9 - View substance registered dossier
ACETO GmbH Hans-Henny-Jahnn-Weg 53 22085 Hamburg Germany Germany Active (20R,25R)-spirost-5-en-3β-ol 208-134-3 512-04-9 - View substance registered dossier
Novo Nordisk A/S Novo Alle 2880 Bagsværd Denmark Denmark Active (22S)-22-carboxy-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic acid 815-717-1 1169630-40-3 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE 610-496-6 500292-86-4 - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active (2E)-3-(4-AMINO-3,5-DIMETHYLPHENYL)PROP-2-ENENITRILE 610-496-6 500292-86-4 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2E)-3-[(tert-butoxycarbonyl)(propan-2-yl)amino]-2-(4-chlorophenyl)prop-2-enoic acid 813-178-7 1489004-27-4 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (2E)-3-Phenylacrylaldehyde 604-377-8 14371-10-9 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active (2E)-3-Phenylacrylaldehyde 604-377-8 14371-10-9 - View substance registered dossier
CENTIPHARM Chemin de la Madeleine 06131 GRASSE FRANCE France France Active (2E)-4,4,4-trifluorobut-2-en-1-ol 835-846-7 83706-94-9 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2E)-N,N-diethyl-3,7-dimethyl-octa-2,6-dien-1-amine 814-576-3 40267-53-6 2020 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2E,4E)-2,4-decadienoic acid 250-149-2 30361-33-2 2020 View substance registered dossier
Výzkumný ústav organických syntéz a.s. č.p. 296 533 54 Rybitví Czech Republic Czech Republic Active (2E,4E,7S)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid, ammonium salt (1:1) 619-006-5 942519-41-7 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy IE Ringaskiddy Cork Ireland Ireland Active (2E,4R)-5-{[1,1’-biphenyl]-4-yl}-4-[(tert-butoxycarbonyl)amino]-2-methylpent-2-enoic acid 695-654-2 1012341-48-8 2014 View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (2R)-1-(2,4-difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one 823-704-7 126918-17-0 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (2R)-1-morpholino-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one 819-998-1 135270-08-5 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R)-1-{5-Amino-2-[1-(benzyloxy)-2-méthyl-2-propanyl]-6-fluoro-1H-indol-1-yl}-3-(benzyloxy)-2-propanol 811-584-9 1294504-67-8 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid 951-764-5 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (2R)-2-aminobutan-1-ol L-tartrate monohydrate 814-787-0 153078-05-8 - View substance registered dossier
Barentz Service S.p.A. via Privata Goito, 8 20037 Paderno Dugnano Italy Italy Active (2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride 700-669-5 2788-28-5 - View substance registered dossier
Biosint S.p.A. Via Murillo 16 04013 Sermoneta Italy Italy Active (2R)-3-cyano-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride 700-669-5 2788-28-5 2019 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (2R)-[(methoxycarbonyl)amino](phenyl)acetic acid 694-843-7 50890-96-5 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1) 947-841-8 - - View substance registered dossier
Selectchemie Italia Srl Via Messina, 47 20154 Milano Italy Italy Active (2R*)-1-[4-(benzyloxy)phenyl]-1-oxo-N-[(2R*)-1-phenoxypropan-2-yl]propan-2-aminium chloride 867-647-6 1179802-09-5 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active (2R*)-1-[4-(benzyloxy)phenyl]-1-oxo-N-[(2R*)-1-phenoxypropan-2-yl]propan-2-aminium chloride 867-647-6 1179802-09-5 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2R,3R)-2,3-Dihydroxybutanedioic acid-(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1) 947-840-2 - - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate 815-196-0 1175536-50-1 - View substance registered dossier
L.C.M. TRADING SPA via Mazzini 33 20099 Sesto San Giovanni Lombardia Italy Italy Active (2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate 408-050-9 76855-69-1 - View substance registered dossier
[Confidential] - - - (2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-[1,2,4]triazol-1-yl-thiobutyramide 609-299-8 368421-58-3 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (2R,3R)-3-(3-(Benzyloxy)phenyl-2-methylpentanoic acid 805-624-4 1367878-84-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid 948-743-8 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate dihydrochloride 948-534-1 1639208-51-7 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (2R,3R,4R)-3,4-Bis(benzyloxy)-2-((benzyloxy)methyl)-5-methoxytetrahydrofuran 857-987-3 64363-77-5 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolane-2-carbonitrile 856-564-0 1355357-49-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3R,4R,5R)-5-(2-Amino-6-chloro-9h-purin-9-yl)-2-[(4-chlorobenzoyloxy)methyl]-4-fluoro-4-methyloxolan-3-yl 4-chlorobenzoate 875-019-8 1294481-82-5 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile 857-885-9 1191237-69-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2R,3S)-N-(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide hydrochloride 425-260-6 244634-31-9 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (2R,3S)-N-(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide hydrochloride 425-260-6 244634-31-9 2020 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (2R,3S,4R)-2-(Hydroxymethyl)-5-methoxytetrahydrofuran-3,4-diol 857-672-0 13039-63-9 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (2R,3S,4R,5R)-2,3,4,6-tetrakis(benzyloxy)-5-hydroxy-1-(4-methylpiperazin-1-yl) hexan-1-one 829-550-7 1431329-04-2 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (2R,3S,4R,5R)-2,3,4,6-tetrakis(benzyloxy)-5-hydroxy-1-(4-methylpiperazin-1-yl) hexan-1-one 829-550-7 1431329-04-2 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-erythro-hexopyranosyl-4-ulose)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl 2-O-[(benzyloxy)carbonyl]-3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside trifluoroacetate (1:2) 953-335-8 1210740-88-7 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-13-{[(3S,4S,6R,8R)-8-methoxy-4,8-dimethyl-1,5-dioxaspiro[2.5]oct-6-yl]oxy}-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl 3,4,6-trideoxy-3-(dimethylamino)--D-xylo-hexopyranoside 953-425-7 217500-75-9 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active (2S)-1,1,2-triphenylethane-1,2-diol 624-788-6 108998-83-0 - View substance registered dossier
DUPONT ASTURIAS, S.L LG Valle de Tamon 33469 Carreno- Asturias Spain Spain Active (2S)-1,1-bis(4-fluorophenyl)propan-2-yl L-alaninate hydrochloride - - - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active (2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene 214-494-2 1135-66-6 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene 214-494-2 1135-66-6 2020 View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active (2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene 214-494-2 1135-66-6 - View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active (2S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile 807-388-8 207557-35-5 2019 View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active (2S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile 807-388-8 207557-35-5 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active (2S)-1-(2-phenylacetyl)pyrrolidine-2-carboxylic acid 928-037-6 2752-38-7 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (2S)-1-[(tert-butyl)oxycarbonyl]-2-methylpyrrolidine-2-carboxylic acid 813-635-0 103336-06-7 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (2S)-1-[(tert-butyl)oxycarbonyl]-2-methylpyrrolidine-2-carboxylic acid 813-635-0 103336-06-7 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active (2S)-2-(benzyloxy)propanal 617-235-5 81445-44-5 - View substance registered dossier
a.c.r.a.f. s.p.a. via guardapasso 1 04011 aprilia Italy Italy Active (2S)-2-[(4-Chlorobenzoyl)oxy]propanoic acid - - - View substance registered dossier
CHEMO BIOSYNTHESIS SRL VIALE ISONZO, 8 20135 MILANO Italy Italy Active (2S)-2-[(8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propanal 861-038-9 3986-89-8 - View substance registered dossier
FARMHISPANIA S.A. Passeig del Riu Besós, 9-10 08160 Montmeló Barcelona Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 - View substance registered dossier
TAMARANG, S.A. Balmes, 84, 4-2 08008 Barcelona Barcelona Spain Spain Cease Manufacture (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 2012 View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 - View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 2018 View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 2010; 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 - View substance registered dossier
MAPIC Europe NV EXCELSIORLAAN 83 1930 ZAVENTEM Belgium Belgium Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 - View substance registered dossier
B.I.G. - OR634 Technische Schoolstraat 43A 2440 Geel Belgium Belgium Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 2011; 2012; 2014; 2020 View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 2010; 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 82717-96-2 2014 View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoic acid 617-393-5 82834-12-6 - View substance registered dossier
LABORATORIOS SERVIER S.L. RIO JARAMA 59 45007 TOLEDO Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoic acid 617-393-5 82834-12-6 - View substance registered dossier
ORIL INDUSTRIE 13 rue Auguste Desgenétais 76210 BOLBEC France France Active (2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoic acid 617-393-5 82834-12-6 2019; 2020; 2021 View substance registered dossier
Midas Pharma Polska Sp. z o.o. Ul. Hankiewicza 2 02-103 Warszawa Poland Poland Active (2S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropanoic acid;hydrochloride 611-205-5 5486-79-3 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active (2S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropanoic acid;hydrochloride 611-205-5 5486-79-3 - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid - - - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1) - - - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active (2S)-2-hydroxy-1-(1-pyrrolidinyl)-1-propanone 601-833-8 122151-38-6 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (2S)-4-amino-2-hydroxy-butanoic acid 670-305-7 40371-51-5 - View substance registered dossier
[Confidential] - - - (2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1) 695-797-0 93601-86-6 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (2S)-but-3-yn-2-yl methanesulfonate 857-677-8 73647-37-7 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2S)-N-(2,6-dimethylphenyl)-1-propyl-piperidine-2-carboxamide 617-525-1 84057-95-4 - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active (2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid 949-609-1 - 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid 949-609-1 - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid 617-180-7 80875-98-5 2019 View substance registered dossier
ORIL INDUSTRIE 13 rue Auguste Desgenétais 76210 BOLBEC France France Active (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid 617-180-7 80875-98-5 2019; 2020; 2021 View substance registered dossier
LABORATORIOS SERVIER S.L. RIO JARAMA 59 45007 TOLEDO Spain Spain Active (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid 617-180-7 80875-98-5 - View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid 617-180-7 80875-98-5 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoic acid 800-213-6 1007881-21-1 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran 835-228-7 211801-54-6 2021 View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active (2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-ol 667-304-9 6564-72-3 2020 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-ol 667-304-9 6564-72-3 2019 View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid — methyl {(4S)-8-fluoro-2-[4-(3methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4yl}acetate — ethyl acetate (1:1:1) 947-432-4 - 2018; 2020 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2S,3S)-2,3-Dihydroxysuccinic acid - (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide (1:2) 954-871-5 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (2S,3S)-di-tert-butyl 3-ethyl-4-oxopyrrolidine-1,2-dicarboxylate 942-044-1 - 2017 View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (2S,3S,4R)-3-ethyl-4-hydroxy-2-(methoxycarbonyl)pyrrolidinium 4-methylbenzenesulfonate 813-641-3 1799733-43-9 - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol succinate 938-481-2 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2S,4aR)-1,1,5,5-tetramethyl-1,3,4,5,6,7-hexahydro-2H-2,4a-methanonaphthalen-7-ol 942-036-8 645413-57-6 2020 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (2S,4Z)-5-amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one;5-amino-[2S-di(methylphenyl)amino]-1,6-diphenyl-4Z-hexen-3-one 423-090-7 156732-13-7 2011; 2018 View substance registered dossier
ITELYUM Purification S.P.A. Via S. Intini n. 2 27015 Landriano (PV) Italy Italy Active (2S,4Z)-5-amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one;5-amino-[2S-di(methylphenyl)amino]-1,6-diphenyl-4Z-hexen-3-one 423-090-7 156732-13-7 2014 View substance registered dossier
[Confidential] - - - (2S,5S,32S)-5-{[(5S,8S,11S,14S,17S)-11-[(2R)-BUTAN-2-YL]-8-{4-[(TERT-BUTOXYCARBONYL)AMINO]BUTYL}-5-(2-TERT-BUTOXY-2-OXOETHYL)-1-(9H-FLUOREN-9-YL)-14-METHYL-3,6,9,12,15,18-HEXAOXO-17-{3-OXO-3-[(TRIPHENYLMETHYL)AMINO]PROPYL}-2-OXA-4,7,10,13,16-PENTAAZAOCTADECAN-18-YL]AMINO}-32-(TERT-BUTOXYCARBONYL)-2,55,55-TRIMETHYL-4,11,20,29,34,53-HEXAOXO-13,16,22,25,54-PENTAOXA-3,10,19,28,33-PENTAAZAHEXAPENTACONTAN-1-OIC ACID 954-943-6 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 255-799-0 42399-49-5 2018 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 255-799-0 42399-49-5 - View substance registered dossier
LusoChimica S.p.A. Via Giotto, 9 23871 Lomagna (Lecco) Italy Italy Active (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 255-799-0 42399-49-5 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 255-799-0 42399-49-5 2018 View substance registered dossier
FINORGA - MOURENX avenue du lac 64150 MOURENX France France Active (2S-cis)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 255-795-9 42399-40-6 - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Active (2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid 279-393-8 80082-65-1 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid 279-393-8 80082-65-1 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (2Z)-7-chloro-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid 618-065-4 877674-77-6 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2α,6α,11R*)-3-benzyl-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol hydrobromide 248-106-8 26918-40-1 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active (3,3-diethoxy-1-propenyl)benzene 230-467-8 7148-78-9 2022 View substance registered dossier
EUROAPI Hungary Ltd. Tó utca 1-5. 1045 Budapest Hungary Hungary Active (3,4-diethoxyphenyl)acetonitrile 248-479-7 27472-21-5 2022 View substance registered dossier
[Confidential] - - - (3-((6-Chlorohexyl)thio)propyl)triethoxysilane and Hexamethylen-1,6-dithio-bis((3-triethoxysilyl) propane) 951-684-0 - - View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active (3-acetyloxy-5-carbonochloridoylphenyl) acetate 855-283-0 39192-49-9 - View substance registered dossier
PALCHEM Rue du Transvaal BP22 62143 ANGRES France France Active (3-bromopropyl)benzene 211-294-7 637-59-2 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (3-bromopropyl)benzene 211-294-7 637-59-2 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (3-Carboxyprop-1-yl)(triphenyl)phosphonium bromide 629-007-2 17857-14-6 - View substance registered dossier
Ricardo Nederland BV Daalsesingel 51 3511 SW Utrecht Netherlands Netherlands Active (