Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:

The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.

Last updated 06 August 2021. Database contains 23376 unique substances and contains information from 104385 dossiers.

Substance identity

Substance name:

EC / List number:

CAS number:

Other Numerical Identifiers:

Administrative data

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Substance data

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View all Registered Substances

Showing 401 - 600 of 26,063 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
(3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-3-carboxylic acid	820-324-3	1428243-24-6	Active	Intermediate	Joint	Intermediate use only	23-03-2018	View substance registered dossier
(3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid	205-334-2	138-59-0	Active	Intermediate	Joint	Intermediate use only	01-10-2019	View substance registered dossier
(3R,4S,5S)-5-azido-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester	433-320-8	-	Active	Intermediate	Joint	Intermediate use only	01-10-2019	View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-trimethylsilyloxyoxan-2-yl]oxy-10-(2-ethoxypropan-2-yloxyimino)-14-ethyl-12,13-dihydroxy-7-methoxy-4-[(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-trimethylsilyloxyoxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one	805-486-5	119665-62-2	Active	Intermediate	Joint	Intermediate use only	13-03-2017	View substance registered dossier
(3R,4S,5S,6R,7R,9R,10Z,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime	603-883-6	134931-01-4	Active	Intermediate	Joint	Intermediate use only	23-08-2016	View substance registered dossier
(3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one	918-279-0	-	Active	Intermediate	Joint	Intermediate use only	26-04-2017	View substance registered dossier
(3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate	603-817-6	134395-00-9	Active	Intermediate	Joint	Intermediate use only	28-09-2017	View substance registered dossier
(3R,5Z)-3-METHYL-5-CYCLOPENTADECEN-1-ONE	851-742-4	464207-51-0	Active	Full	Joint	≥ 1 to < 10 tonnes	28-05-2020	View substance registered dossier
(3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione	603-436-5	13076-17-0	Active	Full	Joint	≥ 1 000 to < 10 000 tonnes	26-07-2018	View substance registered dossier
(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate	228-502-7	6283-74-5	Active	Intermediate	Joint	Intermediate use only	31-08-2018	View substance registered dossier
(3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone	429-980-1	-	Active	NONS	Joint	Tonnage data confidential	15-12-2008	View substance registered dossier
(3S)-3,7-Dimethyl-1-octanol	814-059-2	68680-98-8	Active	Full	Joint	≥ 1 to < 10 tonnes	30-05-2018	View substance registered dossier
(3S)-3,7-dimethylocta-1,6-dien-1-yl acetate	946-529-9	1439355-19-7	Active	Intermediate	Joint	Intermediate use only	24-01-2018	View substance registered dossier
(3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran	619-599-0	915095-94-2	Active	Intermediate	Joint	Intermediate use only	15-04-2020	View substance registered dossier
(3S)-3-thiophen-2-ylsulfanylbutanoic acid	948-811-7	133359-80-5	Active	Intermediate	Joint	Intermediate use only	23-10-2018	View substance registered dossier
(3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate	950-060-5	-	Active	Intermediate	Joint	Intermediate use only	15-01-2020	View substance registered dossier
(3S, 4R)-4-(4’-Fluorophenyl)-3-(3’, 4’-methylenedioxyphenyl)-Nmethylpiperidine	924-787-3	110429-36-2	Active	Intermediate	Joint	Intermediate use only	08-03-2021	View substance registered dossier
(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide	420-380-5	136465-81-1	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine	929-011-7	-	Active	Intermediate	Joint	Intermediate use only	20-04-2018	View substance registered dossier
(3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone	418-650-2	104872-06-2	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	Active	Intermediate	Joint	Intermediate use only	16-05-2018	View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	Active	Intermediate	Joint	Intermediate use only	12-07-2013	View substance registered dossier
(3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one	608-748-5	324763-46-4	Active	Intermediate	Joint	Intermediate use only	13-08-2014	View substance registered dossier
(3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4-	457-410-1	831213-72-0	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol	450-320-3	-	Active	Full	Joint	≥ 0 to < 10 tonnes	16-04-2018	View substance registered dossier
(3S,6E)-3,7,11-trimethyldodeca-6,10-dienal	810-298-1	194934-66-2	Active	Full	Joint	≥ 1 to < 10 tonnes	07-09-2020	View substance registered dossier
(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone	444-350-6	133413-70-4	Active	Intermediate	Joint	Intermediate use only	24-09-2019	View substance registered dossier
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	Active	Full	Joint	≥ 1 000 to < 10 000 tonnes	26-07-2018	View substance registered dossier
(3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate	430-510-2	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile	828-107-5	118316-12-4	Active	Intermediate	Joint	Intermediate use only	05-09-2018	View substance registered dossier
(3β)-17-(1,1,1-trifluoromethanesulfonate)-Androsta-5,16-diene-3,17-diol, 3-(2,2,2-trifluoroacetate)	840-627-4	1802323-89-2	Active	Intermediate	Joint	Intermediate use only	26-06-2019	View substance registered dossier
(3β)-3-[(2,2,2-trifluoroacetyl)oxy]-Androst-5-en-17-one	840-626-9	3798-17-2	Active	Intermediate	Joint	Intermediate use only	26-06-2019	View substance registered dossier
(3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid	228-475-1	6277-14-1	Active	Full	Joint	≥ 0 to < 10 tonnes	27-06-2019	View substance registered dossier
(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-yl butyrate	250-567-5	31316-20-8	Active	Intermediate	Joint	Intermediate use only	06-05-2015	View substance registered dossier
(4'-methyl-3-fluoro[1,1'-biphenyl]-4-yl)-boronic acid	813-651-8	1698890-39-9	Active	Full	Joint	≥ 1 to < 10 tonnes	14-05-2018	View substance registered dossier
(4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone	700-338-5	50372-61-7	Active	Intermediate	Joint	Intermediate use only	05-10-2016	View substance registered dossier
(4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-)	422-960-3	178233-72-2	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(4-(4-(4-dimethylaminobenzyliden-1-yl)-3-methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid	410-430-4	117573-89-4	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone	613-265-8	63590-64-7	Active	Intermediate	Joint	Intermediate use only	25-07-2018	View substance registered dossier
(4-(4-aminophenyl)(4-iminocyclohexa-2,5-dienylidene)methyl)-2-methylaniline hydrochloride	211-189-6	632-99-5	Active	Full	Joint	≥ 1 to < 10 tonnes	25-03-2018	View substance registered dossier
(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester	927-587-4	872728-83-1	Active	Intermediate	Joint	Intermediate use only	28-07-2016	View substance registered dossier
(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid	460-450-2	872728-82-0	Active	Intermediate	Joint	Intermediate use only	17-05-2019	View substance registered dossier
(4-6) PEPTIDE	427-550-8	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl; N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide	423-840-3	14691-89-5	Active	NONS	Joint	Tonnage data confidential	17-02-2012	View substance registered dossier
(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid;hydrate	680-378-7	138624-11-0	Active	Full	Joint	≥ 1 to < 10 tonnes	02-02-2018	View substance registered dossier
(4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile	262-792-6	61437-85-2	Active	Intermediate	Joint	Intermediate use only	09-03-2018	View substance registered dossier
(4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride	406-010-5	88918-84-7	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(4-butoxy-2,3-difluorophenyl)boronic acid	692-793-0	156487-12-6	Active	Full	Joint	≥ 1 to < 10 tonnes	16-05-2018	View substance registered dossier
(4-carboxybutyl)triphenylphosphonium bromide	241-782-5	17814-85-6	Active	Intermediate	Joint	Intermediate use only	15-12-2015	View substance registered dossier
(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone	695-300-7	1103738-30-2	Active	Intermediate	Joint	Intermediate use only	24-11-2020	View substance registered dossier
(4-chlorophenyl)(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol	814-124-5	133545-64-9	Active	Intermediate	Joint	Intermediate use only	10-05-2017	View substance registered dossier
(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid	826-639-2	1817776-86-5	Active	Intermediate	Joint	Intermediate use only	20-07-2020	View substance registered dossier
(4-methoxybiphenyl-3-yl)hydrazine hydrochloride	924-885-6	-	Active	Intermediate	Joint	Intermediate use only	22-10-2012	View substance registered dossier
(4-Methoxyphenyl)diphenylsulfoniumnonaflate	435-570-3	-	Active	NONS	Joint	Tonnage data confidential	24-06-2009	View substance registered dossier
(4-nonylphenoxy)acetic acid	221-486-2	3115-49-9	Active	Full	Joint	≥ 100 to < 1 000 tonnes	04-07-2014	View substance registered dossier
(4-phenylbutyl)phosphinic acid	420-450-5	86552-32-1	Active	Intermediate	Joint	Intermediate use only	09-12-2013	View substance registered dossier
(4-pyridylmethyl)amine	223-092-6	3731-53-1	Active	Intermediate	Joint	Intermediate use only	19-02-2018	View substance registered dossier
(4-pyridylthio)acetyl chloride hydrochloride	248-348-4	27230-51-9	Active	Intermediate	Joint	Intermediate use only	01-07-2020	View substance registered dossier
(4-Sulfamoylpheny)hydrazine monohydrochloride	479-480-2	17852-52-7	Active	Full	Joint	≥ 10 to < 100 tonnes	18-09-2017	View substance registered dossier
(4-Sulfamoylpheny)hydrazine monohydrochloride	479-480-2	17852-52-7	Active	Intermediate	Joint	Intermediate use only	15-05-2018	View substance registered dossier
(4-tert-butyl-2,6-dimethylphenyl)acetonitrile	284-183-4	84803-57-6	Active	Intermediate	Joint	Intermediate use only	30-07-2015	View substance registered dossier
(4aR, 8aR)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)	700-867-1	-	Active	Full	Joint	≥ 1 to < 10 tonnes	02-07-2020	View substance registered dossier
(4aR,8aR)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one hydrochloride	439-750-2	183487-56-1	Active	Full	Joint	≥ 1 to < 10 tonnes	23-05-2018	View substance registered dossier
(4aR,4bS,6aS,7aS,8aS,8bR,8cR)-2-methoxy-4a,6a-dimethyl-4,4a,4b,5,6,6a,7a,8,8a,8b,8c,9-dodecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7(3H)-one	607-934-3	26441-40-7	Active	Intermediate	Joint	Intermediate use only	29-04-2020	View substance registered dossier
(4aR,4bS,6aS,7S,7aS,8aS,8bR,8cR)-7-[2-(1,3-dioxolan-2-yl)ethyl]-2-methoxy-4a,6a-dimethyl-3,4,4a,4b,5,6,6a,7,7a,8,8a,8b,8c,9-tetradecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7-ol	618-226-9	889652-22-6	Active	Intermediate	Joint	Intermediate use only	05-05-2020	View substance registered dossier
(4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR)-5`-methoxy-4a,6a-dimethyl-4,4`,4a,4b,5`,6,6a,7a,8,8a,8b,8c-dodecahydro-3H,3`H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]phenathrene-7,2`-furan]-2(5H)-one	695-294-6	71136-60-2	Active	Intermediate	Joint	Intermediate use only	30-04-2020	View substance registered dossier
(4aR,4bS,6aS,9aS,9bR,11aR)-4a,6a-Dimethyltetradecahydro-1H-indeno[5,4-f]quinoline-2,7-dione	616-323-0	76318-69-9	Active	Intermediate	Joint	Intermediate use only	14-06-2016	View substance registered dossier
(4E)-4-(3,3,4-trimethylcyclopentylidene)butanal	-	-	Active	Full	Joint	≥ 0 to < 10 tonnes	05-03-2021	View substance registered dossier
(4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one	939-401-9	-	Active	Full	Joint	≥ 100 to < 1 000 tonnes	03-11-2020	View substance registered dossier
(4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one	941-406-6	1391712-50-7	Active	Intermediate	Joint	Intermediate use only	08-01-2019	View substance registered dossier
(4E)-4-methyl-5-(4-methylphenyl)pent-4-enal	700-748-4	1226911-69-8	Active	Full	Joint	≥ 0 to < 10 tonnes	20-12-2017	View substance registered dossier
(4E)-5-cyclohexyl-2,4-dimethylpent-4-enal	947-579-4	1449104-34-0	Active	Full	Joint	≥ 1 to < 10 tonnes	08-12-2020	View substance registered dossier
(4E)-N-hydroxy-1,2-benzoxathiin-4(3H)-imine 2,2-dioxide	611-875-9	597563-86-5	Active	Intermediate	Joint	Intermediate use only	28-10-2016	View substance registered dossier
(4R)-2-(1-butoxyethoxy)-4-isopropyl-1-methylenecyclohexane	944-221-9	1429469-15-7	Active	Intermediate	Joint	Intermediate use only	24-02-2017	View substance registered dossier
(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid	849-166-3	83841-00-3	Active	Intermediate	Joint	Intermediate use only	18-05-2021	View substance registered dossier
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine	926-346-0	-	Active	Intermediate	Joint	Intermediate use only	10-11-2017	View substance registered dossier
(4R)-4-methyl-1,3-dioxolan-2-one	437-320-9	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(4R)-6-amino-N,N,4-trimethyl-1,4-dihydro-1,3,5-triazin-2-aminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate	942-402-7	-	Active	Intermediate	Joint	Intermediate use only	30-05-2018	View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one	433-160-9	-	Active	Full	Joint	≥ 1 to < 10 tonnes	18-08-2020	View substance registered dossier
(4R,6R)-4-Hydroxy-2,2,6-trimethylcyclohexanone / 60046-50-6	700-052-0	60046-50-6	Active	Intermediate	Joint	Intermediate use only	20-11-2019	View substance registered dossier
(4R,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol	604-572-8	147128-77-6	Active	Intermediate	Joint	Intermediate use only	06-09-2018	View substance registered dossier
(4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline	807-416-9	1378388-16-9	Active	Intermediate	Joint	Intermediate use only	20-04-2018	View substance registered dossier
(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone	848-798-7	272778-12-8	Active	Intermediate	Joint	Intermediate use only	15-06-2020	View substance registered dossier
(4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide	623-314-5	98674-86-3	Active	Intermediate	Joint	Intermediate use only	26-03-2018	View substance registered dossier
(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide	807-123-6	154127-42-1	Active	Intermediate	Joint	Intermediate use only	21-04-2021	View substance registered dossier
(4S,4aR,5aR,6R,6aR,6bS,7S,9aS,11aS,11bR)-6-hydroxy-9a,11b-dimethyl-9-oxohexadeca hydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-4,7-diyl bis(2,2-dimethylpropanoate)	825-705-8	1235460-56-6	Active	Intermediate	Joint	Intermediate use only	17-07-2018	View substance registered dossier
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)	940-053-5	-	Active	Intermediate	Joint	Intermediate use only	19-01-2017	View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	617-177-0	808-26-4	Active	Intermediate	Joint	Intermediate use only	13-09-2018	View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	811-441-0	1035654-66-0	Active	Intermediate	Joint	Intermediate use only	27-11-2019	View substance registered dossier
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 4-chlorobenzene-1-sulfonic acid	618-775-4	916439-93-5	Active	Intermediate	Joint	Intermediate use only	22-12-2017	View substance registered dossier
(4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)	604-710-7	149934-21-4	Active	Intermediate	Joint	Intermediate use only	12-08-2019	View substance registered dossier
(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid	442-870-8	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonyl chloride, 4-(acetylethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide,	824-717-0	403848-30-6	Active	Intermediate	Joint	Intermediate use only	05-06-2018	View substance registered dossier
(4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide	947-800-4	-	Active	Intermediate	Joint	Intermediate use only	21-06-2018	View substance registered dossier
(4S-trans)-N-(5,6-diidro-6-metil-7,7-diossido-4Htieno[2,3-b]tiopiran-4-il)-acetammide	604-558-1	147086-83-7	Active	Intermediate	Joint	Intermediate use only	09-03-2018	View substance registered dossier
(5-bromothiophen-2-yl)-phenylmethanone	608-584-4	31161-46-3	Active	Intermediate	Joint	Intermediate use only	14-02-2018	View substance registered dossier
(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	Active	Full	Joint	≥ 100 to < 1 000 tonnes	25-11-2020	View substance registered dossier
(5-ethyl-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane	608-586-5	31167-05-2	Active	Intermediate	Joint	Intermediate use only	25-07-2019	View substance registered dossier
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate	604-437-3	144690-92-6	Active	Intermediate	Joint	Intermediate use only	13-05-2013	View substance registered dossier
(5E)-3,5-dimethyloct-5-en-4-ol	947-581-5	2209852-19-5	Active	Full	Joint	≥ 1 to < 10 tonnes	13-03-2020	View substance registered dossier
(5E)-9-(Dichloromethylene)-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-one oxime	700-700-2	1369492-55-6	Active	Intermediate	Joint	Intermediate use only	11-12-2020	View substance registered dossier
(5or8)-aminonaphthalene-2-sulphonic acid	257-269-4	51548-48-2	Active	Full	Joint	≥ 1 to < 10 tonnes	06-04-2018	View substance registered dossier
(5R,6S)-allyl 6-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-7-oxo-3-(propylthio)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate	820-260-6	93603-76-0	Active	Intermediate	Joint	Intermediate use only	28-06-2018	View substance registered dossier
(5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose	815-962-4	1384242-56-1	Active	Intermediate	Joint	Intermediate use only	04-12-2019	View substance registered dossier
(5Z)-5-(2-Methylpropylidene)imidazolidine-2,4-dione	700-726-4	-	Active	Intermediate	Joint	Intermediate use only	15-06-2018	View substance registered dossier
(5Z)-5-Benzylideneimidazolidine-2,4-dione	700-728-5	74805-60-0	Active	Intermediate	Joint	Intermediate use only	24-04-2013	View substance registered dossier
(5´R,8´S,10´R,13´S,14´S)-13´-methyl-1´,2´,6´,7´8´,12´,13´,14´,15´,16´-decahydro-17´H-spiro[1,3-dioxolane-2,3´-[5,10]epoxycyclopenta[a]phenantren]-17´-one	821-898-8	39931-87-8	Active	Intermediate	Joint	Intermediate use only	07-05-2020	View substance registered dossier
(5α)-4,5-epoxy-14-hydroxy-3-methoxymorphinan-6-one	260-887-7	57664-96-7	Active	Intermediate	Joint	Intermediate use only	28-04-2017	View substance registered dossier
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one	251-561-5	33522-95-1	Active	Intermediate	Joint	Intermediate use only	13-02-2019	View substance registered dossier
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride	257-924-4	52446-24-9	Active	Intermediate	Joint	Intermediate use only	16-03-2017	View substance registered dossier
(5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol	207-385-6	467-04-9	Active	Intermediate	Joint	Intermediate use only	30-05-2018	View substance registered dossier
(5α)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one	208-085-8	508-54-3	No longer Valid	Intermediate	Joint	No longer valid	15-03-2018	View substance registered dossier
(5α)-7,8-didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one	282-186-5	84116-46-1	No longer Valid	Intermediate	Joint	No longer valid	12-07-2019	View substance registered dossier
(5α,6α)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride	245-549-9	23277-43-2	Active	Intermediate	Joint	Intermediate use only	19-06-2017	View substance registered dossier
(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate	402-060-7	108225-03-2	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(6-alpha,11-beta,16-alpha,17-alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-androsta-1,4-diene-17-carbothioic acid	617-081-9	80473-92-3	Active	Full	Joint	≥ 1 to < 10 tonnes	21-11-2016	View substance registered dossier
(6-alpha,11-beta,16-alpha,17-alpha)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid	617-084-5	80474-45-9	Active	Full	Joint	≥ 1 to < 10 tonnes	20-12-2016	View substance registered dossier
(6-aminohexyl)carbamic acid	205-581-6	143-06-6	Active	Full	Joint	≥ 100 to < 1 000 tonnes	02-10-2018	View substance registered dossier
(6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid	921-925-4	-	Active	Intermediate	Joint	Intermediate use only	12-05-2017	View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)	939-998-6	-	Cease Manufacture	Intermediate	Joint	Cease manufacture	24-11-2014	View substance registered dossier
(6R,7R)-7-[((2Z)-2-[({2-[(1,1-dimethylethyl)oxy]-1,1-dimethyl-2-oxoethyl}oxy)imino]-2-{2-[(triphenylmethyl)amino]-1,3-thiazol-4-yl}acetyl)amino]-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	617-560-2	84377-83-3	No longer Valid	Full	Joint	No longer valid	15-11-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride	827-945-9	107648-80-6	Active	Intermediate	Joint	Intermediate use only	21-09-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride	600-507-2	103980-44-5	Cease Manufacture	Intermediate	Joint	Cease manufacture	03-04-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acethyl]amino]-3-(hydroxymethyl)-8-oxo-5thia-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid diphenylmethyl ester	609-461-8	376653-36-0	Active	Full	Joint	≥ 1 to < 10 tonnes	30-07-2018	View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acetyl]amino]-3-[(E)-[(3'R)-1'-[(1,1-dimethylethoxy)carbonyl]-2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester	609-463-9	376653-41-7	Active	Full	Joint	≥ 1 to < 10 tonnes	30-07-2018	View substance registered dossier
(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	617-065-1	80370-59-8	Cease Manufacture	Intermediate	Joint	Cease manufacture	03-04-2018	View substance registered dossier
(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid	438-350-5	79349-82-9	Active	Intermediate	Joint	Intermediate use only	21-12-2017	View substance registered dossier
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate	600-349-4	102772-66-7	Active	Intermediate	Joint	Intermediate use only	08-05-2018	View substance registered dossier
(6R,7R,14S)-7-[(2S)-2-hydroxy-3,3-dimethylbut-2-yl]-6,7,8,14-tetrahydro-6,14-ethano-17-northebaine	605-428-7	16614-59-8	Active	Intermediate	Joint	Intermediate use only	18-12-2020	View substance registered dossier
(6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	239-787-2	15690-38-7	Active	Intermediate	Joint	Intermediate use only	19-12-2018	View substance registered dossier
(6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	250-099-1	30246-33-4	Active	Intermediate	Joint	Intermediate use only	16-10-2019	View substance registered dossier
(6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	258-907-4	53994-69-7	Active	Intermediate	Joint	Intermediate use only	16-10-2019	View substance registered dossier
(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	244-870-1	22252-43-3	Active	Intermediate	Joint	Intermediate use only	16-12-2019	View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	Active	Intermediate	Joint	Intermediate use only	10-07-2019	View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid	261-491-7	58909-56-1	Cease Manufacture	Full	Joint	Cease manufacture	03-05-2018	View substance registered dossier
(6RS,7RS)3,5,5,6,7,8,8-heptamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde	482-190-9	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate	949-377-1	-	Active	Intermediate	Joint	Intermediate use only	10-05-2019	View substance registered dossier
(6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1)	605-420-3	165950-84-5	Active	Full	Joint	≥ 1 to < 10 tonnes	26-11-2020	View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide	431-140-4	-	Active	Intermediate	Joint	Intermediate use only	13-11-2017	View substance registered dossier
(6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1)	603-080-0	125572-93-2	Active	Full	Joint	≥ 1 to < 10 tonnes	17-12-2020	View substance registered dossier
(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one	615-123-0	7055-53-0	Active	Intermediate	Joint	Intermediate use only	18-09-2017	View substance registered dossier
(7-Hydroxy-2-naphthyl)-trimethylammonium methyl sulphate	807-380-4	377734-55-9	No longer Valid	Full	Joint	No longer valid	26-03-2018	View substance registered dossier
(7-Methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile	617-813-7	861960-34-1	Active	Full	Joint	≥ 1 to < 10 tonnes	11-05-2018	View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile	461-670-1	-	Active	Intermediate	Joint	Intermediate use only	13-02-2019	View substance registered dossier
(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-ium chloride	690-742-7	1266664-66-7	Active	Full	Joint	≥ 10 to < 100 tonnes	20-05-2020	View substance registered dossier
(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase (enzyme substance)	611-406-8	56645-46-6	Active	Full	Joint	≥ 1 to < 10 tonnes	01-10-2018	View substance registered dossier
(8R,9S,10R,13S,14S,17R)-10,13-dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)	926-987-6	-	Active	Intermediate	Joint	Intermediate use only	05-03-2018	View substance registered dossier
(8R,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17,-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2´-[1,3]dioxolan]-17-ol	610-527-3	50407-76-6	Active	Intermediate	Joint	Intermediate use only	06-05-2020	View substance registered dossier
(8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one	608-630-3	31528-46-8	Active	Full	Joint	≥ 0 to < 10 tonnes	10-01-2019	View substance registered dossier
(8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-8,9,11,12,14,15,16,17-octahydro-7H-cyclopenta[a]phenanthren-6-one	641-994-1	571-92-6	Active	Intermediate	Joint	Intermediate use only	01-04-2020	View substance registered dossier
(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,4,7,8,10,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolane]-17-carbonitrile	601-332-4	114882-16-5	Active	Intermediate	Joint	Intermediate use only	23-08-2016	View substance registered dossier
(8S,13S,14S,17R)-17-allyl-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17ol	849-739-8	141299-95-8	Active	Intermediate	Joint	Intermediate use only	13-04-2021	View substance registered dossier
(8S,13S,14S,17R)-17-allyl-17-hydroxy-13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one	849-749-2	23760-34-1	Active	Intermediate	Joint	Intermediate use only	13-04-2021	View substance registered dossier
(8S,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one	600-229-1	10161-33-8	Active	Intermediate	Joint	Intermediate use only	07-11-2017	View substance registered dossier
(9beta,11beta)-3,20-dioxo-9,11-epoxypregna-1,4,16-trien-21-yl acetate	600-439-3	103466-44-0	Active	Intermediate	Joint	Intermediate use only	07-03-2018	View substance registered dossier
(9R,10S,13S)-10,13-dimethyl-17-(2-methyl-1,3-dioxolan-2-yl)spiro[1,2,4,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,2'-1,3-dioxolane]	611-207-6	5488-51-7	Active	Intermediate	Joint	Intermediate use only	19-11-2018	View substance registered dossier
(alpha-cyanobenzyl)malonic acid diethyl ester	922-463-6	-	Active	Intermediate	Joint	Intermediate use only	17-02-2017	View substance registered dossier
(aminoalkyl) hydrogen thiosulfate	-	-	Active	Full	Joint	≥ 1 to < 10 tonnes	05-01-2021	View substance registered dossier
(benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium	259-105-7	54326-11-3	Active	Full	Joint	≥ 10 to < 100 tonnes	04-05-2018	View substance registered dossier
(benzothiazol-2-ylthio)acetic acid	228-565-0	6295-57-4	Active	Full	Joint	≥ 100 to < 1 000 tonnes	27-07-2021	View substance registered dossier
(benzothiazol-2-ylthio)succinic acid	401-450-4	95154-01-1	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(benzothiazol-2-ylthio)succinic acid	401-450-4	95154-01-1	No longer Valid	Full	Joint	No longer valid	30-04-2020	View substance registered dossier
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate	603-290-2	128625-52-5	Active	Full	Joint	≥ 1 to < 10 tonnes	24-05-2021	View substance registered dossier
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate	603-290-2	128625-52-5	Active	Intermediate	Joint	Intermediate use only	07-12-2018	View substance registered dossier
(benzylamine)trifluoroboron	211-802-7	696-99-1	Active	Full	Joint	≥ 1 to < 10 tonnes	18-05-2018	View substance registered dossier
(Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate	436-000-6	159010-67-0	Active	Full	Joint	≥ 1 tonnes	20-03-2020	View substance registered dossier
(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate	442-520-4	-	Active	Full	Joint	≥ 1 tonnes	12-02-2020	View substance registered dossier
(Bromomethyl)cyclobutane	700-027-4	17247-58-4	Cease Manufacture	Intermediate	Joint	Cease manufacture	14-12-2011	View substance registered dossier
(Bromomethylphenyl-4')-2 benzonitrile	601-327-7	114772-54-2	Active	Intermediate	Joint	Intermediate use only	31-05-2013	View substance registered dossier
(butylamine)[[2,2'-thiobis[4-(1,1,3,3-tetramethylbutyl)phenolato]](2-)-O,O',S]nickel	238-523-3	14516-71-3	Active	Full	Joint	≥ 100 to < 1 000 tonnes	14-07-2021	View substance registered dossier
(C16 or C18-n-alkyl)(C16 or C18-n-alkyl)ammonium 2-((C16 or C18-n-alkyl)(C16 or C18-n-alkyl)carbamoyl)benzenesulfonate	402-460-1	-	Active	NONS	Joint	Tonnage data confidential	10-11-2008	View substance registered dossier
(carboxylatomethyl)dimethyltetradecylammonium	220-006-9	2601-33-4	Active	Full	Joint	≥ 0 to < 10 tonnes	05-03-2021	View substance registered dossier
(carboxylatomethyl)dodecyldimethylammonium	211-669-5	683-10-3	Active	Full	Joint	≥ 10 to < 100 tonnes	13-11-2018	View substance registered dossier
(carboxylatomethyl)hexadecyldimethylammonium	211-748-4	693-33-4	Active	Full	Joint	≥ 10 to < 100 tonnes	15-03-2021	View substance registered dossier
(carboxymethyl)dimethyl-3-[(1-oxododecyl)amino]propylammonium hydroxide	224-292-6	4292-10-8	Active	Full	Joint	≥ 100 to < 1 000 tonnes	25-03-2021	View substance registered dossier
(carboxymethyl)dimethyl-3-[(1-oxooctyl)amino]propylammonium hydroxide	277-600-6	73772-46-0	Active	Full	Joint	≥ 1 to < 10 tonnes	17-07-2020	View substance registered dossier
(carboxymethyl)dimethyl-3-[(1-oxotetradecyl)amino]propylammonium hydroxide	261-684-6	59272-84-3	Active	Full	Joint	≥ 1 to < 10 tonnes	25-03-2020	View substance registered dossier
(carboxymethyl)dimethyl[3-[(1-oxoundecenyl)amino]propyl]ammonium hydroxide	308-783-3	98510-75-9	Active	Full	Joint	≥ 10 to < 100 tonnes	10-06-2016	View substance registered dossier
(chloromethyl)bis(4-fluorophenyl)methylsilane	401-200-4	85491-26-5	Cease Manufacture	Full	Joint	Cease manufacture	29-10-2012	View substance registered dossier
(chloromethyl)diethoxymethylsilane	218-657-9	2212-10-4	Active	Full	Joint	≥ 1 to < 10 tonnes	15-11-2019	View substance registered dossier
(chloromethyl)triethoxysilane	239-311-3	15267-95-5	Active	Full	Joint	≥ 0 to < 10 tonnes	17-04-2020	View substance registered dossier
(chloromethyl)vinylbenzene	250-005-9	30030-25-2	Active	Full	Joint	≥ 1 to < 10 tonnes	28-03-2018	View substance registered dossier
(cis)-4-[2-[2-((1S,2S,5S)-6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]morpholine	700-519-9	-	Active	Intermediate	Joint	Intermediate use only	13-01-2020	View substance registered dossier
(cyclohex-3-en-1-yl)methyl 2-hydroxypropanoate	946-283-2	1864727-96-7	Active	Full	Joint	≥ 0 to < 10 tonnes	18-01-2019	View substance registered dossier
(D)-p-hydroxyphenylglycine-2-hydroxyethylester, hydrochloride	433-310-3	-	Active	NONS	Joint	Tonnage data confidential	04-02-2011	View substance registered dossier
(diethylamino)acetonitrile	221-130-6	3010-02-4	Active	Intermediate	Joint	Intermediate use only	28-02-2018	View substance registered dossier
(dihydro-3,3-diphenyl-3H-furan-2-ylidene)dimethylammonium bromide	253-649-9	37743-18-3	Active	Full	Joint	≥ 1 to < 10 tonnes	28-03-2019	View substance registered dossier
(Dimethoxy(methyl)silyl)methyl 2-methacrylate	479-600-3	-	Active	Full	Joint	≥ 1 tonnes	02-12-2016	View substance registered dossier
(E)-(4-methoxy-2,3,6-trimethylphenyl)-3-buten-2-one	263-760-4	62924-31-6	Active	Intermediate	Joint	Intermediate use only	18-05-2018	View substance registered dossier
(E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyloxime	456-110-8	-	Active	Intermediate	Joint	Intermediate use only	07-04-2017	View substance registered dossier
(E)-(7R,11R)-3,7,11,15-tetramethylhexadec-2-ene-1-ol	416-120-5	150-86-7	Active	NONS	Joint	Tonnage data confidential	12-05-2017	View substance registered dossier
(E)-1,3-dichloropropene	431-460-4	10061-02-6	Active	Intermediate	Joint	Intermediate use only	13-06-2017	View substance registered dossier
(E)-1,3-dichloropropene	431-460-4	10061-02-6	Active	Intermediate	Joint	Intermediate use only	26-04-2012	View substance registered dossier
(E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate (1:1)	227-154-3	5685-86-9	Active	Intermediate	Joint	Intermediate use only	12-03-2018	View substance registered dossier
(E)-1,4-dibromobut-2-ene	212-472-7	821-06-7	Cease Manufacture	Intermediate	Joint	Cease manufacture	18-05-2018	View substance registered dossier
(E)-1-(2,4,4-trimethyl-2-cyclohexen-1-yl)-2-buten-1-one	254-663-8	39872-57-6	Active	Full	Joint	≥ 1 to < 10 tonnes	06-04-2018	View substance registered dossier
(E)-1-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-2-buten-1-one	245-844-2	23726-93-4	Active	Full	Joint	≥ 10 to < 100 tonnes	08-07-2019	View substance registered dossier
(E)-1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-buten-1-one	245-842-1	23726-91-2	Active	Full	Joint	≥ 10 to < 100 tonnes	18-05-2021	View substance registered dossier
(E)-1-(2,6,6-trimethyl-1-cyclohexen-1-yl)pent-1-en-3-one	264-140-6	63429-28-7	Active	Full	Joint	≥ 1 to < 10 tonnes	29-11-2019	View substance registered dossier
(E)-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-buten-1-one	246-430-4	24720-09-0	Active	Full	Joint	≥ 10 to < 100 tonnes	24-08-2018	View substance registered dossier

Showing 401 - 600 of 26,063 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
[Confidential]	-	-	-	(3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-3-carboxylic acid	820-324-3	1428243-24-6	-	View substance registered dossier
Roche Pharma AG (1)	Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany	Germany	Active	(3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid	205-334-2	138-59-0	2014; 2019	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Cease Manufacture	(3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid	205-334-2	138-59-0	2020	View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik	Kalkstrasse 218 51377 Leverkusen Germany	Germany	Cease Manufacture	(3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid	205-334-2	138-59-0	2021	View substance registered dossier
S.A. Ajinomoto OmniChem N.V.	Industrial Research Park Fleming 1348 Louvain-la-Neuve Belgium	Belgium	Cease Manufacture	(3R,4S,5S)-5-azido-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester	433-320-8	-	2020	View substance registered dossier
Roche Pharma AG (1)	Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany	Germany	Active	(3R,4S,5S)-5-azido-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester	433-320-8	-	2010; 2014; 2019	View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik	Kalkstrasse 218 51377 Leverkusen Germany	Germany	Active	(3R,4S,5S)-5-azido-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester	433-320-8	-	-	View substance registered dossier
Ercros SA	Avenida Diagonal 593-595 08014 Barcelona Spain	Spain	Active	(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-trimethylsilyloxyoxan-2-yl]oxy-10-(2-ethoxypropan-2-yloxyimino)-14-ethyl-12,13-dihydroxy-7-methoxy-4-[(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-trimethylsilyloxyoxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one	805-486-5	119665-62-2	-	View substance registered dossier
[Confidential]	-	-	-	(3R,4S,5S,6R,7R,9R,10Z,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime	603-883-6	134931-01-4	-	View substance registered dossier
Ercros SA	Avenida Diagonal 593-595 08014 Barcelona Spain	Spain	Active	(3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one	918-279-0	-	-	View substance registered dossier
Krka, d. d., Novo mesto	Smarjeska cesta 6 SI-8501 Novo mesto Slovenia	Slovenia	Active	(3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate	603-817-6	134395-00-9	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	(3R,5Z)-3-METHYL-5-CYCLOPENTADECEN-1-ONE	851-742-4	464207-51-0	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	(3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione	603-436-5	13076-17-0	-	View substance registered dossier
PURAC Biochem	Arkelsedijk 46 4206AC Gorinchem Netherlands	Netherlands	Active	(3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione	603-436-5	13076-17-0	2011; 2015	View substance registered dossier
Total Corbion PLA bv	Arkelsedijk 46 4206AC Gorinchem Netherlands	Netherlands	Active	(3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione	603-436-5	13076-17-0	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate	228-502-7	6283-74-5	-	View substance registered dossier
All'Chem	rue Marceau 03108 MONTLUCON CEDEX France	France	Active	(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate	228-502-7	6283-74-5	2018	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone	429-980-1	-	-	View substance registered dossier
-	-	-	-	(3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone	429-980-1	-	-	View substance registered dossier
TAKASAGO TEPL-OR(1)	12 rue Torricelli 75017 Paris France	France	Active	(3S)-3,7-Dimethyl-1-octanol	814-059-2	68680-98-8	-	View substance registered dossier
TAKASAGO TICSA-Producer/Importer	Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain	Spain	Active	(3S)-3,7-dimethylocta-1,6-dien-1-yl acetate	946-529-9	1439355-19-7	-	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Active	(3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran	619-599-0	915095-94-2	2019	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran	619-599-0	915095-94-2	-	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Active	(3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran	619-599-0	915095-94-2	2019	View substance registered dossier
DUKE CHEM, S.A.	Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain	Spain	Active	(3S)-3-thiophen-2-ylsulfanylbutanoic acid	948-811-7	133359-80-5	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	(3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate	950-060-5	-	-	View substance registered dossier
Thermofisher Scientific Cork Ltd.	Currabinny P43 AY66 Carrigaline Co. Cork Ireland	Ireland	Active	(3S, 4R)-4-(4’-Fluorophenyl)-3-(3’, 4’-methylenedioxyphenyl)-Nmethylpiperidine	924-787-3	110429-36-2	2021	View substance registered dossier
CHEMI S.p.A.	Via dei lavoratori, 54 20092 Cinisello balsamo Lombardia Italy	Italy	Active	(3S, 4R)-4-(4’-Fluorophenyl)-3-(3’, 4’-methylenedioxyphenyl)-Nmethylpiperidine	924-787-3	110429-36-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority.	-	-	Active	(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide	420-380-5	136465-81-1	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide	420-380-5	136465-81-1	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine	929-011-7	-	-	View substance registered dossier
Patheon Austria GmbH & Co KG	St. Peterstrasse 25 A-4020 Linz Austria	Austria	Active	(3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone	418-650-2	104872-06-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Austrian competent national authority.	-	-	Active	(3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone	418-650-2	104872-06-2	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone	418-650-2	104872-06-2	-	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	-	View substance registered dossier
MSD International GmbH	Ballydine - Kilsheelan 0 Clonmel Ireland	Ireland	Active	(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	2011; 2015	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	-	View substance registered dossier
[Confidential]	-	-	-	(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate	436-150-2	-	-	View substance registered dossier
Novartis Integrated Services Limited	Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland	Ireland	Active	(3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one	608-748-5	324763-46-4	2014	View substance registered dossier
Novartis Grimsby Limited	Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom	United Kingdom	No longer Valid	(3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one	608-748-5	324763-46-4	2021	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4-	457-410-1	831213-72-0	-	View substance registered dossier
-	-	-	-	(3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4-	457-410-1	831213-72-0	-	View substance registered dossier
TAKASAGO TEPL-OR(1)	12 rue Torricelli 75017 Paris France	France	Active	(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol	450-320-3	-	2018	View substance registered dossier
TAKASAGO TEPL-Importer	12 rue Torricelli 75017 Paris France	France	Active	(3S,6E)-3,7,11-trimethyldodeca-6,10-dienal	810-298-1	194934-66-2	2020	View substance registered dossier
TAKASAGO TEPL-OR(1)	12 rue Torricelli 75017 Paris France	France	Active	(3S,6E)-3,7,11-trimethyldodeca-6,10-dienal	810-298-1	194934-66-2	-	View substance registered dossier
Bayer AG	Kaiser-Wilhelm-Allee 51373 Leverkusen Germany	Germany	Active	(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone	444-350-6	133413-70-4	2010; 2018	View substance registered dossier
Bayer Animal Health GmbH	Alfred Nobel Straße 50 40789 Monheim Germany	Germany	Active	(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone	444-350-6	133413-70-4	-	View substance registered dossier
Total Corbion PLA bv	Arkelsedijk 46 4206AC Gorinchem Netherlands	Netherlands	Active	(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	-	View substance registered dossier
PURAC Biochem	Arkelsedijk 46 4206AC Gorinchem Netherlands	Netherlands	Active	(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione	224-832-0	4511-42-6	2011; 2015	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate	430-510-2	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	(3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate	430-510-2	-	-	View substance registered dossier
Farmabios Spa	Via Pavia, 1 27027 Gropello Cairoli PV Italy	Italy	Active	(3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile	828-107-5	118316-12-4	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	(3β)-17-(1,1,1-trifluoromethanesulfonate)-Androsta-5,16-diene-3,17-diol, 3-(2,2,2-trifluoroacetate)	840-627-4	1802323-89-2	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	(3β)-3-[(2,2,2-trifluoroacetyl)oxy]-Androst-5-en-17-one	840-626-9	3798-17-2	-	View substance registered dossier
Indena S.p.A.	Viale Ortles, 12 20139 Milan Italy	Italy	Active	(3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid	228-475-1	6277-14-1	2019	View substance registered dossier
DSM Nutritional Products France SAS	1 boulevard d'Alsace F-68128 Village-Neuf France	France	Active	(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-yl butyrate	250-567-5	31316-20-8	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	(4'-methyl-3-fluoro[1,1'-biphenyl]-4-yl)-boronic acid	813-651-8	1698890-39-9	-	View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A.	Mallorca 262 08008 Barcelona Barcelona Spain	Spain	Active	(4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone	700-338-5	50372-61-7	2016	View substance registered dossier
QUIMICA SINTETICA, S.A.	C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain	Spain	Active	(4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone	700-338-5	50372-61-7	2016	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority.	-	-	Active	(4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-)	422-960-3	178233-72-2	-	View substance registered dossier
ELKEM SILICONES FRANCE S.A.S.	Immeuble DANICA 21, Avenue Georges Pompidou 69003 Lyon France	France	Active	(4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-)	422-960-3	178233-72-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-)	422-960-3	178233-72-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(4-(4-(4-dimethylaminobenzyliden-1-yl)-3-methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid	410-430-4	117573-89-4	-	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany	Germany	Active	(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone	613-265-8	63590-64-7	2018	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Active	(4-(4-aminophenyl)(4-iminocyclohexa-2,5-dienylidene)methyl)-2-methylaniline hydrochloride	211-189-6	632-99-5	-	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester	927-587-4	872728-83-1	2016	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Active	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester	927-587-4	872728-83-1	-	View substance registered dossier
AllessaProduktion GmbH	Alt-Fechenheim 34 60386 Frankfurt am Main Germany	Germany	Active	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid	460-450-2	872728-82-0	2012; 2019	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid	460-450-2	872728-82-0	-	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Active	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid	460-450-2	872728-82-0	2013; 2016	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Active	(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid	460-450-2	872728-82-0	2012; 2014; 2016	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority.	-	-	Active	(4-6) PEPTIDE	427-550-8	-	-	View substance registered dossier
United Initiators GmbH	Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany	Germany	Active	(4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl; N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide	423-840-3	14691-89-5	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	(4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl; N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide	423-840-3	14691-89-5	2012	View substance registered dossier
MSD International GmbH	Ballydine - Kilsheelan 0 Clonmel Ireland	Ireland	Active	(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid;hydrate	680-378-7	138624-11-0	-	View substance registered dossier
Globalquimia, S.L.U.	Avenida Diagonal, 519, 1º 1ª 08029 Barcelona Spain Spain	Spain	Active	(4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile	262-792-6	61437-85-2	-	View substance registered dossier
Menadiona SL	Pol Ind Mas Puigvert, Ctra Nacional II Km 680, 5 08389 Palafolls Barcelona Spain	Spain	Active	(4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile	262-792-6	61437-85-2	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	(4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride	406-010-5	88918-84-7	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride	406-010-5	88918-84-7	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	(4-butoxy-2,3-difluorophenyl)boronic acid	692-793-0	156487-12-6	-	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	(4-carboxybutyl)triphenylphosphonium bromide	241-782-5	17814-85-6	-	View substance registered dossier
sanofi chimie	82 avenue Raspail 94250 Gentilly France	France	Active	(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone	695-300-7	1103738-30-2	2020	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone	695-300-7	1103738-30-2	-	View substance registered dossier
Derivados Químicos S.A.	Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain	Spain	Active	(4-chlorophenyl)(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol	814-124-5	133545-64-9	-	View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG	Binger Strasse 173 55216 Ingelheim am Rhein Germany	Germany	Active	(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid	826-639-2	1817776-86-5	-	View substance registered dossier
Bidachem S.p.A.	S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy	Italy	Active	(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid	826-639-2	1817776-86-5	-	View substance registered dossier
Synthesia, a.s.	Semtín103 53002 Pardubice Czech Republic	Czech Republic	Active	(4-methoxybiphenyl-3-yl)hydrazine hydrochloride	924-885-6	-	-	View substance registered dossier
-	-	-	-	(4-Methoxyphenyl)diphenylsulfoniumnonaflate	435-570-3	-	-	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(4-Methoxyphenyl)diphenylsulfoniumnonaflate	435-570-3	-	-	View substance registered dossier
BASF Performance Products France SA	Rue de la Chapelle 28 68330 Huningue France	France	Cease Manufacture	(4-nonylphenoxy)acetic acid	221-486-2	3115-49-9	2015	View substance registered dossier
BASF Lampertheim GmbH	Chemiestrasse 22 68619 Lampertheim Germany	Germany	Active	(4-nonylphenoxy)acetic acid	221-486-2	3115-49-9	2014	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	(4-nonylphenoxy)acetic acid	221-486-2	3115-49-9	-	View substance registered dossier
Corden Pharma Latina S.p.A.	Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy	Italy	Cease Manufacture	(4-phenylbutyl)phosphinic acid	420-450-5	86552-32-1	2017	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority.	-	-	Active	(4-phenylbutyl)phosphinic acid	420-450-5	86552-32-1	-	View substance registered dossier
INTEROR	49, rue d'Ostende F-62100 CALAIS France	France	Active	(4-pyridylmethyl)amine	223-092-6	3731-53-1	-	View substance registered dossier
Intertek Italia SpA_ITAzo	Via Miglioli 2/A 20063 CERNUSCO SUL NAVIGLIO Milano Italy	Italy	Active	(4-pyridylthio)acetyl chloride hydrochloride	248-348-4	27230-51-9	-	View substance registered dossier
Fine and Performance Chemicals Ltd	Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom	United Kingdom	No longer Valid	(4-pyridylthio)acetyl chloride hydrochloride	248-348-4	27230-51-9	2021	View substance registered dossier
Corden Pharma Latina S.p.A.	Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy	Italy	Active	(4-pyridylthio)acetyl chloride hydrochloride	248-348-4	27230-51-9	-	View substance registered dossier
[Confidential]	-	-	-	(4-Sulfamoylpheny)hydrazine monohydrochloride	479-480-2	17852-52-7	-	View substance registered dossier
Siemsgluss Ibérica, S.A.	Pol. Ind. Sant Antoni, parcela 6, nave 2 08620 Sant Vicenç dels Horts Barcelona Spain	Spain	Active	(4-Sulfamoylpheny)hydrazine monohydrochloride	479-480-2	17852-52-7	-	View substance registered dossier
Biesterfeld Spezialchemie GmbH	Ferdinandstr. 41 20095 Hamburg Germany	Germany	Active	(4-Sulfamoylpheny)hydrazine monohydrochloride	479-480-2	17852-52-7	-	View substance registered dossier
Excella GmbH & Co. KG	Nuernberger Str. 12 90537 Feucht Germany	Germany	Active	(4-Sulfamoylpheny)hydrazine monohydrochloride	479-480-2	17852-52-7	2018	View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH	Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany	Germany	Active	(4-tert-butyl-2,6-dimethylphenyl)acetonitrile	284-183-4	84803-57-6	-	View substance registered dossier
N.V. Ajinomoto OmniChem S.A.	Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium	Belgium	Active	(4aR, 8aR)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)	700-867-1	-	2020	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Active	(4aR, 8aR)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)	700-867-1	-	2020	View substance registered dossier
Janssen Pharmaceutica N.V.	Turnhoutseweg 30 2340 Beerse Belgium	Belgium	Active	(4aR,8aR)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one hydrochloride	439-750-2	183487-56-1	2010; 2012; 2018	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(4aR,4bS,6aS,7aS,8aS,8bR,8cR)-2-methoxy-4a,6a-dimethyl-4,4a,4b,5,6,6a,7a,8,8a,8b,8c,9-dodecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7(3H)-one	607-934-3	26441-40-7	2020	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(4aR,4bS,6aS,7S,7aS,8aS,8bR,8cR)-7-[2-(1,3-dioxolan-2-yl)ethyl]-2-methoxy-4a,6a-dimethyl-3,4,4a,4b,5,6,6a,7,7a,8,8a,8b,8c,9-tetradecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7-ol	618-226-9	889652-22-6	2020	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR)-5`-methoxy-4a,6a-dimethyl-4,4`,4a,4b,5`,6,6a,7a,8,8a,8b,8c-dodecahydro-3H,3`H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]phenathrene-7,2`-furan]-2(5H)-one	695-294-6	71136-60-2	2020	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	(4aR,4bS,6aS,9aS,9bR,11aR)-4a,6a-Dimethyltetradecahydro-1H-indeno[5,4-f]quinoline-2,7-dione	616-323-0	76318-69-9	-	View substance registered dossier
V. MANE FILS	620 route de Grasse 06620 Le Bar sur Loup France	France	Active	(4E)-4-(3,3,4-trimethylcyclopentylidene)butanal	-	-	-	View substance registered dossier
Solenis Belgium B.V.B.A.	Industrieweg 15 3583 Beringen Belgium	Belgium	Cease Manufacture	(4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one	939-401-9	-	2016	View substance registered dossier
Mare S.p.A.	Via Verdi No. 3 20002 Ossona Fraz. Asmonte Italy	Italy	Active	(4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one	939-401-9	-	2020	View substance registered dossier
Solenis Netherlands B.V.	Pesetastraat 62 2991 XT Barendrecht Netherlands	Netherlands	Active	(4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one	939-401-9	-	-	View substance registered dossier
Derivados Químicos S.A.	Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain	Spain	Active	(4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one	941-406-6	1391712-50-7	-	View substance registered dossier
Patheon Austria GmbH & Co KG	St. Peterstrasse 25 A-4020 Linz Austria	Austria	Active	(4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one	941-406-6	1391712-50-7	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	(4E)-4-methyl-5-(4-methylphenyl)pent-4-enal	700-748-4	1226911-69-8	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	(4E)-5-cyclohexyl-2,4-dimethylpent-4-enal	947-579-4	1449104-34-0	2020	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	(4E)-N-hydroxy-1,2-benzoxathiin-4(3H)-imine 2,2-dioxide	611-875-9	597563-86-5	-	View substance registered dossier
Symrise AG	Mühlenfeldstraße 1 37603 Holzminden Germany	Germany	Active	(4R)-2-(1-butoxyethoxy)-4-isopropyl-1-methylenecyclohexane	944-221-9	1429469-15-7	-	View substance registered dossier
Syngenta Hellas Single Member S.A.C.I.	Anthousas Avenue 153 49 Anthousa - Attiki Greece	Greece	Active	(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid	849-166-3	83841-00-3	2021	View substance registered dossier
CABB Oy	Kemirantie 1 FI-67701 Kokkola Finland	Finland	Active	(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid	849-166-3	83841-00-3	2020	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine	926-346-0	-	-	View substance registered dossier
Sterling Pharma Solutions Ltd	Dudley NE23 7QG Cramlington Northumberland United Kingdom	United Kingdom	No longer Valid	(4R)-4-methyl-1,3-dioxolan-2-one	437-320-9	-	2021	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.	-	-	Active	(4R)-4-methyl-1,3-dioxolan-2-one	437-320-9	-	-	View substance registered dossier
EXPANSIA	Route d'Avignon BP 6 30390 ARAMON France	France	Active	(4R)-6-amino-N,N,4-trimethyl-1,4-dihydro-1,3,5-triazin-2-aminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate	942-402-7	-	-	View substance registered dossier
PCAS	21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France	France	Active	(4R)-6-amino-N,N,4-trimethyl-1,4-dihydro-1,3,5-triazin-2-aminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate	942-402-7	-	2018	View substance registered dossier
Visolis, B.V.	Urmonderbaan 22 6167 RD Geleen Netherlands	Netherlands	Active	(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one	433-160-9	-	-	View substance registered dossier
[Confidential]	-	-	-	(4R,6R)-4-Hydroxy-2,2,6-trimethylcyclohexanone / 60046-50-6	700-052-0	60046-50-6	-	View substance registered dossier
DUKE CHEM, S.A.	Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain	Spain	Active	(4R,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol	604-572-8	147128-77-6	-	View substance registered dossier
Gilead Sciences Ireland UC	IDA Business &Technology Park Carrigtohill Cork Cork Ireland	Ireland	Active	(4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline	807-416-9	1378388-16-9	-	View substance registered dossier
Derivados Químicos S.A.	Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain	Spain	Active	(4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline	807-416-9	1378388-16-9	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline	807-416-9	1378388-16-9	-	View substance registered dossier
Krka, d. d., Novo mesto	Smarjeska cesta 6 SI-8501 Novo mesto Slovenia	Slovenia	Active	(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone	848-798-7	272778-12-8	2020	View substance registered dossier
Arran Chemical Company Ltd	Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland	Ireland	Active	(4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide	623-314-5	98674-86-3	-	View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd	Długosza 67 43-188 Orzesze Poland	Poland	Active	(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide	807-123-6	154127-42-1	-	View substance registered dossier
CHEMO BIOSYNTHESIS SRL	VIALE ISONZO, 8 20135 MILANO Italy	Italy	Active	(4S,4aR,5aR,6R,6aR,6bS,7S,9aS,11aS,11bR)-6-hydroxy-9a,11b-dimethyl-9-oxohexadeca hydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-4,7-diyl bis(2,2-dimethylpropanoate)	825-705-8	1235460-56-6	-	View substance registered dossier
Hovione FarmaCiencia SA	Sete Casas 2674-506 Loures Portugal	Portugal	Active	(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)	940-053-5	-	2017	View substance registered dossier
Hovione Limited	Loughbeg not available Ringaskiddy County Cork Ireland	Ireland	Active	(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)	940-053-5	-	2017	View substance registered dossier
Curia Italy S.r.l.	VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy	Italy	Active	(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	617-177-0	808-26-4	-	View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos	Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal	Portugal	Active	(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	617-177-0	808-26-4	-	View substance registered dossier
Hovione FarmaCiencia SA	Sete Casas 2674-506 Loures Portugal	Portugal	Active	(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	617-177-0	808-26-4	-	View substance registered dossier
Curia Italy S.r.l.	VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy	Italy	Active	(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	811-441-0	1035654-66-0	-	View substance registered dossier
Curia Italy S.r.l.	VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy	Italy	Active	(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 4-chlorobenzene-1-sulfonic acid	618-775-4	916439-93-5	-	View substance registered dossier
Curia Italy S.r.l.	VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy	Italy	Active	(4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)	604-710-7	149934-21-4	-	View substance registered dossier
Pfizer Ireland Pharmaceuticals	n/a P43 X3336 Ringaskiddy Cork Ireland	Ireland	Active	(4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)	604-710-7	149934-21-4	2013; 2018; 2019	View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.	-	-	Active	(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid	442-870-8	-	-	View substance registered dossier
-	-	-	-	(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid	442-870-8	-	-	View substance registered dossier
DUKE CHEM, S.A.	Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain	Spain	Active	(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonyl chloride, 4-(acetylethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide,	824-717-0	403848-30-6	-	View substance registered dossier
DUKE CHEM, S.A.	Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain	Spain	Active	(4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide	947-800-4	-	-	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	(4S-trans)-N-(5,6-diidro-6-metil-7,7-diossido-4Htieno[2,3-b]tiopiran-4-il)-acetammide	604-558-1	147086-83-7	-	View substance registered dossier
ERREGIERRE SPA	Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy	Italy	Active	(5-bromothiophen-2-yl)-phenylmethanone	608-584-4	31161-46-3	-	View substance registered dossier
Miwon Europe GmbH	Zeppelinstraße 26 D-47638 Straelen Germany	Germany	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	-	View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 119	Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5-5 Planta 28050 Madrid Spain	Spain	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	-	View substance registered dossier
ARKEMA PHOTOCURES	420 rue d'Estienne d'Orves 92700 Colombes France	France	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	-	View substance registered dossier
IGM Resins Ltd	c/o Baldwins, Wynyard Park House Wynyard Avenue TS22 5TB Wynyard Durham United Kingdom	United Kingdom	No longer Valid	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	2021	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	2015	View substance registered dossier
IGM Resins B.V.	Gompenstraat 49 5145 RA Waalwijk Netherlands	Netherlands	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	2020	View substance registered dossier
ARKEMA FRANCE	420 rue d'Estienne d'Orves 92700 COLOMBES France	France	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	2018	View substance registered dossier
RAHN NL B.V. (30)	Westplein 11 3016BM Rotterdam Netherlands	Netherlands	Active	(5-ethyl-1,3-dioxan-5-yl)methyl acrylate	266-380-7	66492-51-1	-	View substance registered dossier
FERRANIA CHEMICALS S.R.L.	Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy	Italy	Active	(5-ethyl-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane	608-586-5	31167-05-2	2019	View substance registered dossier
CHINOIN Pharmaceutical and Chemical Works Private Co. Ltd.	TO Utca 1-5 POB 110 1325 BUDAPEST Ujpest Hungary	Hungary	Active	(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate	604-437-3	144690-92-6	-	View substance registered dossier
FIRMENICH GRASSE SAS OR 1	Parc Industriel Les Bois de Grasse 06130 Grasse France	France	Active	(5E)-3,5-dimethyloct-5-en-4-ol	947-581-5	2209852-19-5	-	View substance registered dossier
Syngenta Hellas Single Member S.A.C.I.	Anthousas Avenue 153 49 Anthousa-Attiki Greece	Greece	Active	(5E)-9-(Dichloromethylene)-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-one oxime	700-700-2	1369492-55-6	2014; 2018; 2020	View substance registered dossier
[Confidential]	-	-	-	(5E)-9-(Dichloromethylene)-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-one oxime	700-700-2	1369492-55-6	-	View substance registered dossier
Global Product Compliance (Europe) AB	IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden	Sweden	Active	(5or8)-aminonaphthalene-2-sulphonic acid	257-269-4	51548-48-2

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