Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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reaction products of diazotized p-amino-acetanilide, coupledwith 6-amino-4-hydroxynaphthalene-2-sulfonic acid, subsequently hydrolyzed, diazotized and coupled with 8- aminonaphthalene-2-sulfonic acid and 6-amino-4-hydroxynaphthalene-2-sulfonic acid, potassium salts
948-490-3 - Active Full Joint ≥ 10 to < 100 tonnes 25-11-2020 View substance registered dossier
(3E)-4-[(1S,3aS,4R,7aS)-1,7a-dimethyloctahydro-4H-1,4-methanoinden-4-yl]pent-3-en-2-one
948-498-7 143785-33-5 Active Full Individual ≥ 1 to < 10 tonnes 25-07-2019 View substance registered dossier
Reaction products of 2,3-epoxypropyl phenyl ether and 2,2'-iminodi(ethylamine)
948-518-4 - Active Full Joint ≥ 10 to < 100 tonnes 06-05-2020 View substance registered dossier
Reaction products of Soya and Linseed Oil Fatty Acids with Bisphenol A diglycidylether
948-520-5 - Active Full Individual ≥ 10 to < 100 tonnes 07-07-2021 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate dihydrochloride
948-534-1 1639208-51-7 Active Intermediate Joint Intermediate use only 20-08-2018 View substance registered dossier
4-(3-formyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzonitrile
948-544-6 2141947-89-7 Active Intermediate Joint Intermediate use only 22-08-2019 View substance registered dossier
difluoro-2,2,4,5-tetrafluoro-5-(trifluoromethoxy)-1,3-dioxolan-4-yl]oxy}acetyl fluoride
948-548-8 1260592-86-6 Active Intermediate Individual Intermediate use only 20-02-2019 View substance registered dossier
Reaction products of diazotised 2-amino-5-{[2-(sulfooxy)ethyl]sulfonyl}benzenesulfonic acid coupled with 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid under acidic conditions, further coupled with diazotised reaction products of 2,4,6-trifluoro-1,3,5-triazine with 2-[(2-anilinoethyl)sulfonyl]ethyl hydrogen sulfate and 2,4-diaminobenzenesulfonic acid (1:1:1) under alkaline conditions, potassium sodium salts
948-562-4 - Active Full Joint ≥ 0 to < 10 tonnes 03-04-2019 View substance registered dossier
Slimes and sludges, electrolytic refining of tin, lead and silver containing alloy
948-652-3 - Active Full Joint ≥ 10 to < 100 tonnes 21-11-2018 View substance registered dossier
Reaction mass of L-Glutamic acid, N-(1-oxooctyl)-, sodium salt and N-L-glutamyl-L-glutamic acid, N'-(1-oxooctyl)-, sodium salt
948-708-7 - Active Full Joint ≥ 1 to < 10 tonnes 18-01-2022 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid
948-743-8 - Active Intermediate Joint Intermediate use only 04-10-2018 View substance registered dossier
methyl piperazine-1-carboxylate, phosphate
948-751-1 - Active Intermediate Joint Intermediate use only 30-10-2018 View substance registered dossier
Isoalkanes, C16-C18
948-766-3 - Active Full Joint ≥ 1 000 to < 10 000 tonnes 13-01-2022 View substance registered dossier
Soybean oil epoxidized, methyl esters
948-767-9 - Active Intermediate Joint Intermediate use only 04-06-2019 View substance registered dossier
trisodium (2S)-2,6-bis(3-carboxylatopropanamido)hexanoate
948-778-9 - Active Full Joint ≥ 10 to < 100 tonnes 11-10-2019 View substance registered dossier
(3S)-3-thiophen-2-ylsulfanylbutanoic acid
948-811-7 133359-80-5 Active Intermediate Joint Intermediate use only 23-10-2018 View substance registered dossier
1-Bromo-3-(3-methoxy-2-piperidinyl)-2-propanone Hydrobromide
948-812-2 - Active Intermediate Joint Intermediate use only 10-10-2018 View substance registered dossier
reaction mass of N1,N3-bis(3-aminopropyl)-2-methyl-cyclohexane-1,3-diamine and N1,N3-bis(3-aminopropyl)-4-methyl-cyclohexane-1,3-diamine
948-816-4 - Cease Manufacture Full Joint Cease manufacture 07-01-2020 View substance registered dossier
Hydrocarbons from mixed waste plastics, thermo-mechanical depolymerization condensate
948-892-9 - Active Intermediate Individual Intermediate use only 19-03-2019 View substance registered dossier
Essential oil of Blue tansy obtained from the flowers and leaves of Tanacetum annuum (Asteraceae) by steam distillation
948-910-5 - No longer Valid Full Joint No longer valid 13-12-2019 View substance registered dossier
Reaction products of (E)-5-((4-amino-5-methoxy-2-methylphenyl)diazenyl)-3-((phenylsulfonyl)oxy)naphthalene-2,7-disulfonic acid condensate with cyanurchloride, then condensate with (E)-7-amino-4-hydroxy-3-((2-methoxy-5-sulfophenyl)diazenyl)naphthalene-2-sulfonic acid, finally condensate with aniline, potassium salts
948-912-6 - Active Full Joint ≥ 1 to < 10 tonnes 06-12-2018 View substance registered dossier
Oligomerisation products of plasma treated triglycerides, C16-18 (even numbered) and C18 (unsaturated)
948-916-8 - Active Full Joint ≥ 1 to < 10 tonnes 12-12-2019 View substance registered dossier
Benzenesulfonic acid, C10-24-branched and linear alkyl derivs., magnesium salts, overbased
948-935-1 - Active Full Joint ≥ 100 to < 1 000 tonnes 30-10-2019 View substance registered dossier
Reaction mass of bis(2-ethylhexyl) adipate and cyclohexyl 2-ethylhexyl adipate and dicyclohexyl adipate
948-946-1 - Active Full Joint ≥ 1 to < 10 tonnes 10-06-2021 View substance registered dossier
Pyrolysis oil from waste rubbers and tires
948-949-8 - Active Intermediate Joint Intermediate use only 31-01-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active reaction products of diazotized p-amino-acetanilide, coupledwith 6-amino-4-hydroxynaphthalene-2-sulfonic acid, subsequently hydrolyzed, diazotized and coupled with 8- aminonaphthalene-2-sulfonic acid and 6-amino-4-hydroxynaphthalene-2-sulfonic acid, potassium salts 948-490-3 - 2018; 2020 View substance registered dossier
PFW Aroma Ingredients B.V. Veemweg 29-31 3771 MT Barneveld Gelderland Netherlands Netherlands Active (3E)-4-[(1S,3aS,4R,7aS)-1,7a-dimethyloctahydro-4H-1,4-methanoinden-4-yl]pent-3-en-2-one 948-498-7 143785-33-5 2019 View substance registered dossier
Blue Cube Germany Assets GmbH & Co. KG Buetzflether Sand 2 21683 Stade Germany Germany Active Reaction products of 2,3-epoxypropyl phenyl ether and 2,2'-iminodi(ethylamine) 948-518-4 - - View substance registered dossier
Blue Cube Netherlands B.V. Axelsedam 3a 4531HH Terneuzen Netherlands Netherlands Active Reaction products of 2,3-epoxypropyl phenyl ether and 2,2'-iminodi(ethylamine) 948-518-4 - - View substance registered dossier
Blue Cube Chemicals Italy S.r.l.   Corso Giuseppe Garibaldi 86 20121 Milano Italy Italy Active Reaction products of 2,3-epoxypropyl phenyl ether and 2,2'-iminodi(ethylamine) 948-518-4 - - View substance registered dossier
Blue Cube Germany Assets GmbH & Co. KG Buetzflether Sand 2 21683 Stade Germany Germany Active Reaction products of Soya and Linseed Oil Fatty Acids with Bisphenol A diglycidylether 948-520-5 - 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate dihydrochloride 948-534-1 1639208-51-7 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active 4-(3-formyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzonitrile 948-544-6 2141947-89-7 2019 View substance registered dossier
Solvay Specialty Polymers Italy S.p.A. Viale Lombardia 20 20021 BOLLATE Italy Italy Active difluoro-2,2,4,5-tetrafluoro-5-(trifluoromethoxy)-1,3-dioxolan-4-yl]oxy}acetyl fluoride 948-548-8 1260592-86-6 2019 View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Active Reaction products of diazotised 2-amino-5-{[2-(sulfooxy)ethyl]sulfonyl}benzenesulfonic acid coupled with 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid under acidic conditions, further coupled with diazotised reaction products of 2,4,6-trifluoro-1,3,5-triazine with 2-[(2-anilinoethyl)sulfonyl]ethyl hydrogen sulfate and 2,4-diaminobenzenesulfonic acid (1:1:1) under alkaline conditions, potassium sodium salts 948-562-4 - - View substance registered dossier
Metallo Belgium NV Nieuwe Dreef 33 B-2340 Beerse Antwerp Belgium Belgium Active Slimes and sludges, electrolytic refining of tin, lead and silver containing alloy 948-652-3 - - View substance registered dossier
ZSCHIMMER & SCHWARZ ITALIANA S.p.A. Via Angelo Ariotto No. 1 13038 TRICERRO (VERCELLI) Italy Italy Active Reaction mass of L-Glutamic acid, N-(1-oxooctyl)-, sodium salt and N-L-glutamyl-L-glutamic acid, N'-(1-oxooctyl)-, sodium salt 948-708-7 - 2021; 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid 948-743-8 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active methyl piperazine-1-carboxylate, phosphate 948-751-1 - - View substance registered dossier
Monument Chemical Haven 1972 Ketenislaan 3 9130 Kallo Belgium Belgium Active Isoalkanes, C16-C18 948-766-3 - 2022 View substance registered dossier
Oleon GmbH Industriestrasse 10 46446 Emmerich am Rhein Germany Germany Active Soybean oil epoxidized, methyl esters 948-767-9 - 2019 View substance registered dossier
[Confidential] - - - trisodium (2S)-2,6-bis(3-carboxylatopropanamido)hexanoate 948-778-9 - - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (3S)-3-thiophen-2-ylsulfanylbutanoic acid 948-811-7 133359-80-5 - View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active 1-Bromo-3-(3-methoxy-2-piperidinyl)-2-propanone Hydrobromide 948-812-2 - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture reaction mass of N1,N3-bis(3-aminopropyl)-2-methyl-cyclohexane-1,3-diamine and N1,N3-bis(3-aminopropyl)-4-methyl-cyclohexane-1,3-diamine 948-816-4 - 2021 View substance registered dossier
Cassandra Processing AB SJÖHAGSVÄGEN 14 72132 Västerås Sweden Sweden Active Hydrocarbons from mixed waste plastics, thermo-mechanical depolymerization condensate 948-892-9 - - View substance registered dossier
Augustus Oils Ltd Augustus House Mill Lane GU34 2QG Alton Hampshire United Kingdom United Kingdom No longer Valid Essential oil of Blue tansy obtained from the flowers and leaves of Tanacetum annuum (Asteraceae) by steam distillation 948-910-5 - 2021 View substance registered dossier
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active Reaction products of (E)-5-((4-amino-5-methoxy-2-methylphenyl)diazenyl)-3-((phenylsulfonyl)oxy)naphthalene-2,7-disulfonic acid condensate with cyanurchloride, then condensate with (E)-7-amino-4-hydroxy-3-((2-methoxy-5-sulfophenyl)diazenyl)naphthalene-2-sulfonic acid, finally condensate with aniline, potassium salts 948-912-6 - - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active Reaction products of (E)-5-((4-amino-5-methoxy-2-methylphenyl)diazenyl)-3-((phenylsulfonyl)oxy)naphthalene-2,7-disulfonic acid condensate with cyanurchloride, then condensate with (E)-7-amino-4-hydroxy-3-((2-methoxy-5-sulfophenyl)diazenyl)naphthalene-2-sulfonic acid, finally condensate with aniline, potassium salts 948-912-6 - - View substance registered dossier
Green Frix SA Rue de la forêt 2 7522 Blandain Belgium Belgium Active Oligomerisation products of plasma treated triglycerides, C16-18 (even numbered) and C18 (unsaturated) 948-916-8 - - View substance registered dossier
Afton Chemical S.R.L. (Woluwe) Alma Court Lenneke Marelaan, 8 B-1932 St-Stevens-Woluwe Belgium Belgium Active Benzenesulfonic acid, C10-24-branched and linear alkyl derivs., magnesium salts, overbased 948-935-1 - 2019 View substance registered dossier
Proviron Industries NV Zone 2 Georges Gilliotstraat 60 2620 Hemiksem Antwerpen Belgium Belgium Active Reaction mass of bis(2-ethylhexyl) adipate and cyclohexyl 2-ethylhexyl adipate and dicyclohexyl adipate 948-946-1 - - View substance registered dossier
Pyrum Innovations International SA 1D Waistroos 5445 Schengen Luxembourg Luxembourg Active Pyrolysis oil from waste rubbers and tires 948-949-8 - 2019 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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