Registered substances

Data platform availability banner - registered substances

The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
Lactic acid
200-018-0 50-21-5 Active Full Joint ≥ 100 to < 1 000 tonnes 04-01-2023 View substance registered dossier
Hydrocortisone
200-020-1 50-23-7 Active Intermediate Joint Intermediate use only 06-12-2022 View substance registered dossier
Prednisolone
200-021-7 50-24-8 Active Full Joint ≥ 10 to < 100 tonnes 04-05-2022 View substance registered dossier
Estradiol
200-023-8 50-28-2 Active Full Joint ≥ 1 to < 10 tonnes 10-11-2021 View substance registered dossier
2,3-dichlorobenzoic acid
200-039-5 50-45-3 Active Intermediate Joint Intermediate use only 17-04-2020 View substance registered dossier
Desipramine
200-040-0 50-47-5 Active Intermediate Joint Intermediate use only 08-02-2018 View substance registered dossier
Amitriptyline
200-041-6 50-48-6 Active Intermediate Joint Intermediate use only 11-10-2018 View substance registered dossier
Imipramine
200-042-1 50-49-7 Active Intermediate Joint Intermediate use only 08-03-2018 View substance registered dossier
Thioridazine
200-044-2 50-52-2 Active Intermediate Joint Intermediate use only 19-03-2018 View substance registered dossier
Chlorpromazine
200-045-8 50-53-3 Active Intermediate Joint Intermediate use only 16-05-2017 View substance registered dossier
D-ribose
200-059-4 50-69-1 Active Full Joint ≥ 0 to < 10 tonnes 03-05-2019 View substance registered dossier
D-ribose
200-059-4 50-69-1 Active Intermediate Joint Intermediate use only 15-09-2020 View substance registered dossier
O-acetylsalicylic acid
200-064-1 50-78-2 Active Full Joint ≥ 100 to < 1 000 tonnes 02-04-2013 View substance registered dossier
O-acetylsalicylic acid
200-064-1 50-78-2 Active Intermediate Individual Intermediate use only 27-03-2015 View substance registered dossier
2-hydroxy-p-toluic acid
200-068-3 50-85-1 Active Intermediate Joint Intermediate use only 22-09-2021 View substance registered dossier
2-hydroxy-p-toluic acid
200-068-3 50-85-1 No longer Valid Full Joint No longer valid 15-02-2018 View substance registered dossier
Thymidine
200-070-4 50-89-5 Active Full Joint ≥ 1 000 to < 10 000 tonnes 02-09-2014 View substance registered dossier
α-phenyl-1H-benzimidazole-2-methanol
200-073-0 50-97-5 Active Full Joint ≥ 1 to < 10 tonnes 14-10-2022 View substance registered dossier
Ephedrine hydrochloride
200-074-6 50-98-6 Active Intermediate Joint Intermediate use only 08-11-2018 View substance registered dossier
2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether
200-076-7 51-03-6 Active Full Joint ≥ 1 000 to < 10 000 tonnes 28-03-2022 View substance registered dossier
2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether
200-076-7 51-03-6 No longer Valid Full Individual No longer valid 02-07-2013 View substance registered dossier
Procaine hydrochloride
200-077-2 51-05-8 Active Intermediate Joint Intermediate use only 02-07-2018 View substance registered dossier
Benzimidazole
200-081-4 51-17-2 Active Full Joint ≥ 10 to < 100 tonnes 09-12-2021 View substance registered dossier
Fluorouracil
200-085-6 51-21-8 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
2,4-dinitrophenol
200-087-7 51-28-5 Active Full Joint ≥ 100 to < 1 000 tonnes 09-03-2022 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Lactic acid 200-018-0 50-21-5 2021 View substance registered dossier
Sacco S.r.l. via Alessandro Manzoni 29a 22071 Cadorago Como Italy Italy Active Lactic acid 200-018-0 50-21-5 - View substance registered dossier
Chementors Oy Smart Chemistry Park Raisionkaari 55 21200 Raisio Finland Finland Active Lactic acid 200-018-0 50-21-5 2021 View substance registered dossier
Purac Biochem bv Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active Lactic acid 200-018-0 50-21-5 2018; 2021; 2022 View substance registered dossier
Galactic Place d'Escanaffles 23 7760 Escanaffles Belgium Belgium Active Lactic acid 200-018-0 50-21-5 2022 View substance registered dossier
BIOFER SpA Via Tommaso da Cazzaniga 9/6 20121 Milano Milano Italy Italy Active Hydrocortisone 200-020-1 50-23-7 2012; 2013; 2021 View substance registered dossier
NEWCHEM S.P.A. VIA EDMONDO DE AMICIS 47 20123 MILANO ITALY Italy Italy Active Hydrocortisone 200-020-1 50-23-7 2013 View substance registered dossier
RSI ChemRep Europe Ltd (P001) 27-30 Merchants Quay Merchants House 8 Dublin Ireland Ireland Active Hydrocortisone 200-020-1 50-23-7 2021; 2022 View substance registered dossier
[Confidential] - - - Hydrocortisone 200-020-1 50-23-7 - View substance registered dossier
VALDEPHARM Parc Industriel d'Incarville CS10606 27106 Val de Reuil France France Active Hydrocortisone 200-020-1 50-23-7 2012 View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy Italy Active Hydrocortisone 200-020-1 50-23-7 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Cease Manufacture Hydrocortisone 200-020-1 50-23-7 2015 View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active Prednisolone 200-021-7 50-24-8 - View substance registered dossier
CURIA SPAIN, S.A.U. Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain Spain Active Prednisolone 200-021-7 50-24-8 - View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy Italy Active Prednisolone 200-021-7 50-24-8 2011 View substance registered dossier
[Confidential] - - - Prednisolone 200-021-7 50-24-8 - View substance registered dossier
Steroid SpA Viale Spagna 156 20093 Cologno Monzese Milano Italy Italy Active Prednisolone 200-021-7 50-24-8 - View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Cease Manufacture Prednisolone 200-021-7 50-24-8 2022 View substance registered dossier
NEWCHEM S.P.A. VIA EDMONDO DE AMICIS 47 20123 MILANO ITALY Italy Italy Active Prednisolone 200-021-7 50-24-8 2013 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active Estradiol 200-023-8 50-28-2 2012; 2017; 2021 View substance registered dossier
VALDEPHARM Parc Industriel d'Incarville CS10606 27106 Val de Reuil France France Active Estradiol 200-023-8 50-28-2 2012; 2018 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active 2,3-dichlorobenzoic acid 200-039-5 50-45-3 2020 View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active Desipramine 200-040-0 50-47-5 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Cease Manufacture Amitriptyline 200-041-6 50-48-6 2022 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active Amitriptyline 200-041-6 50-48-6 - View substance registered dossier
Sigma-Aldrich Ireland Ltd Vale Road . Arklow Co. Wicklow Ireland Ireland Active Amitriptyline 200-041-6 50-48-6 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active Imipramine 200-042-1 50-49-7 - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active Imipramine 200-042-1 50-49-7 - View substance registered dossier
PCAS Finland Oy Messukentänkatu 8 20210 TURKU Finland Finland Active Imipramine 200-042-1 50-49-7 - View substance registered dossier
Trifarma S.p.A. Via G. Guarini Matteucci 1 20162 Milan (MI) Italy Italy Active Thioridazine 200-044-2 50-52-2 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active Chlorpromazine 200-045-8 50-53-3 - View substance registered dossier
LUCAS MEYER COSMETICS 13 rue Ella Maillart Campus Eiffel - Bâtiment Edison 91300 MASSY Ile-De-France France France Active D-ribose 200-059-4 50-69-1 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active D-ribose 200-059-4 50-69-1 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active D-ribose 200-059-4 50-69-1 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active D-ribose 200-059-4 50-69-1 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active D-ribose 200-059-4 50-69-1 - View substance registered dossier
QUIMDIS SAS 71, rue Anatole France 92532 Levallois-Perret France France Active D-ribose 200-059-4 50-69-1 - View substance registered dossier
NOVACYL SAS 21 chemin de la Sauvegarde « 21 Ecully Parc » - CS 33167 69134 ECULLY CEDEX France France Active O-acetylsalicylic acid 200-064-1 50-78-2 - View substance registered dossier
Sanofi Winthrop Industrie 20, avenue Raymond Aron 92165 Antony Cedex France France Active O-acetylsalicylic acid 200-064-1 50-78-2 2015 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active 2-hydroxy-p-toluic acid 200-068-3 50-85-1 - View substance registered dossier
Zach System ZI La Croix Cadeau 49242 Avrillé France France Active 2-hydroxy-p-toluic acid 200-068-3 50-85-1 2021 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden No longer Valid 2-hydroxy-p-toluic acid 200-068-3 50-85-1 2021 View substance registered dossier
[Confidential] - - - Thymidine 200-070-4 50-89-5 - View substance registered dossier
Nalco Europe B.V. Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands Netherlands Active α-phenyl-1H-benzimidazole-2-methanol 200-073-0 50-97-5 2022 View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France France Active Ephedrine hydrochloride 200-074-6 50-98-6 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active Ephedrine hydrochloride 200-074-6 50-98-6 2018 View substance registered dossier
ENDURA S.p.A. Viale Pietramellara, 5 40121 Bologna Italy Italy Active 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether 200-076-7 51-03-6 2014; 2020; 2022 View substance registered dossier
Copyr S.p.A. Via G. Stephenson 73 20157 Milano Italy Italy No longer Valid 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether 200-076-7 51-03-6 2017 View substance registered dossier
ADL Biopharma S.L.U Avda. Antibióticos, 59 - 61 24009 León Spain Spain Active Procaine hydrochloride 200-077-2 51-05-8 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Procaine hydrochloride 200-077-2 51-05-8 2017; 2018 View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active Procaine hydrochloride 200-077-2 51-05-8 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active Benzimidazole 200-081-4 51-17-2 2017; 2018 View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active Benzimidazole 200-081-4 51-17-2 2019 View substance registered dossier
[Confidential] - - - Benzimidazole 200-081-4 51-17-2 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Fluorouracil 200-085-6 51-21-8 - View substance registered dossier
JSC Grindeks 53 Krustpils St LV 1057 Riga Latvia Latvia Cease Manufacture Fluorouracil 200-085-6 51-21-8 2022 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active Fluorouracil 200-085-6 51-21-8 2012 View substance registered dossier
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active 2,4-dinitrophenol 200-087-7 51-28-5 2021 View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Active 2,4-dinitrophenol 200-087-7 51-28-5 2022 View substance registered dossier
Reach & Colours Trade Kft Levente u. 14/a 2161 Csomád Hungary Hungary Active 2,4-dinitrophenol 200-087-7 51-28-5 2021 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.